Detailed information NTG0798611

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P1A14_RS09965
• Genome accession: NZ_CP119338
• Coordinates: 2019490..2020533 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain N09HSA11
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2014490..2025533

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1A14_RS09935 (P1A14_09935)	-	2014912..2016168 (-)	1257	WP_001789555.1	aminopeptidase	-
P1A14_RS09940 (P1A14_09940)	-	2016171..2016371 (-)	201	WP_000180460.1	DUF1128 family protein	-
P1A14_RS09945 (P1A14_09945)	-	2016518..2016982 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
P1A14_RS09950 (P1A14_09950)	-	2016989..2017264 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
P1A14_RS09955 (P1A14_09955)	-	2017542..2018759 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
P1A14_RS09960 (P1A14_09960)	vraR	2018871..2019500 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
P1A14_RS09965 (P1A14_09965)	vraS	2019490..2020533 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
P1A14_RS09970 (P1A14_09970)	liaF	2020530..2021231 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
P1A14_RS09975 (P1A14_09975)	-	2021246..2021632 (-)	387	WP_001110179.1	hypothetical protein	-
P1A14_RS09980 (P1A14_09980)	map	2021849..2022607 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
P1A14_RS09985 (P1A14_09985)	-	2023019..2024005 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
P1A14_RS09990 (P1A14_09990)	-	2024436..2024849 (-)	414	WP_001670387.1	hypothetical protein	-
P1A14_RS09995 (P1A14_09995)	-	2024878..2024988 (-)	111	WP_031775032.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=798611 P1A14_RS09965 WP_001017131.1 2019490..2020533(-) (vraS) [Staphylococcus aureus strain N09HSA11]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=798611 P1A14_RS09965 WP_001017131.1 2019490..2020533(-) (vraS) [Staphylococcus aureus strain N09HSA11]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1