Detailed information NTG0798072

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: PY824_RS10865
• Genome accession: NZ_CP119172
• Coordinates: 2085866..2088307 (-)
• Length: 813 a.a.
• NCBI ID: WP_039671295.1
• Uniprot ID: A0AAP8FXB9
• Organism: Streptococcus macedonicus strain SGM CIP105683
• Function: degradation of ComX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2084479..2085735	2085866..2088307	flank	131

Gene organization within MGE regions

Location: 2084479..2088307

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PY824_RS10860 (PY824_10860)	-	2084479..2085735 (-)	1257	WP_115265893.1	ISL3 family transposase	-
PY824_RS10865 (PY824_10865)	clpC	2085866..2088307 (-)	2442	WP_039671295.1	ATP-dependent Clp protease ATP-binding subunit	Regulator

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90274.57 Da
• Isoelectric Point: 5.6473

>NTDB_id=798072 PY824_RS10865 WP_039671295.1 2085866..2088307(-) (clpC) [Streptococcus macedonicus strain SGM CIP105683]
MSEYSIKMQEVFSVAQYQAARFESPYLESWHVLLAMVAIHDSVAGLTFAEYQTKIAYEEYEAAAVLAIGKSPLTDVDRVH
FVEQSKALSDVLAFAESICQVTGGNEIGTEHVLYAMLLNLDLFATRLLEVAGFKNKEDGDAARLIDLRKSLARNAGFTKE
NIKAIHELRKPKKSTMGGAFSEMLKPQSTAEDLSDFTRDLTEMARQGKLEPVIGREKEISRMVQVLSRKTKNNPVLVGEA
GVGKTALAYGLAQRIVNGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIISDIEEDGHIILFIDEVHTIMGSGSG
IDSTLDAANILKPALARGTLHMVGATTQEEYQKHLEKDAALSRRFAKITIEEPSVEDAYQILLGLKKSYEDFHNVVISDE
AVLTAVKAAHRYLTSKNLPDSAIDLLDEASATVQGLVKKEAPATLTPADKAILEGDFKLATKLLKESRKKPNRKPTAVTE
DDIMATLSRLSGIPVEKMTQADSKKYLNLEKEFHKRVIGQDSAISAISRAIRRNQAGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEIEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATTLRDEKTVGFGARDMAHDYEAMQKRIMEELKKTYRPEFINRIDEKVVFHN
LTQENMRDVVKIMVKPLIATLAEKDITLKFQPSALKYLAEIGYDPEMGARPLRRTLQDKVEDELSELILSGELASGNTLK
IGVSKGQLKFDIA

Nucleotide

• Length: 2442 bp

>NTDB_id=798072 PY824_RS10865 WP_039671295.1 2085866..2088307(-) (clpC) [Streptococcus macedonicus strain SGM CIP105683]
ATGAGTGAGTATTCGATAAAAATGCAAGAGGTTTTCAGTGTTGCTCAATACCAAGCAGCGCGTTTTGAAAGCCCATATTT
AGAAAGTTGGCACGTCCTTTTAGCTATGGTTGCTATCCATGACTCAGTCGCAGGGCTAACATTTGCGGAATACCAAACTA
AAATTGCTTATGAAGAATATGAAGCGGCAGCTGTTTTAGCCATTGGGAAATCACCGTTAACGGATGTTGACAGAGTTCAT
TTTGTGGAACAATCTAAAGCTCTTAGTGATGTTTTAGCATTTGCTGAGTCTATTTGTCAGGTGACTGGTGGTAACGAAAT
CGGGACAGAACACGTGCTTTATGCGATGTTGTTAAACCTTGATTTATTTGCCACACGTTTGTTAGAGGTTGCTGGTTTTA
AAAACAAAGAAGACGGTGACGCTGCTCGTTTGATTGATTTGCGTAAGAGTTTGGCACGTAATGCTGGTTTTACAAAGGAA
AATATCAAAGCTATTCATGAACTTCGTAAGCCGAAAAAATCGACAATGGGCGGTGCTTTTTCTGAAATGCTGAAACCACA
GTCAACAGCGGAGGATTTGTCAGATTTCACGCGTGATTTGACAGAGATGGCACGTCAAGGAAAATTAGAACCTGTTATTG
GTCGTGAAAAAGAAATTTCTCGTATGGTGCAGGTGCTTAGCCGCAAAACGAAAAACAATCCAGTTTTAGTAGGGGAAGCT
GGTGTTGGTAAAACGGCTCTTGCTTACGGTTTGGCACAGCGAATTGTCAATGGTGCGATTCCGTATGAACTCCAAGACAT
GCGTGTTTTAGAGCTTGATATGATGAGCGTTGTGGCTGGTACGCGATTCCGTGGTGATTTTGAAGAACGCATGAACCAAA
TCATCTCAGATATTGAGGAAGACGGTCATATTATTCTATTCATTGACGAAGTGCATACGATTATGGGTTCAGGCTCTGGA
ATTGACAGCACTTTGGATGCGGCTAATATTTTAAAACCAGCACTTGCGCGTGGTACGCTTCATATGGTTGGTGCGACAAC
GCAAGAAGAATATCAAAAACATCTCGAAAAAGATGCGGCGCTTTCTCGCCGTTTTGCTAAGATTACCATTGAAGAACCAA
GTGTTGAAGATGCTTACCAAATCTTGCTTGGACTAAAGAAATCATATGAAGATTTTCATAATGTGGTGATTTCTGATGAA
GCTGTTTTAACGGCTGTCAAAGCTGCGCATCGCTATTTGACAAGTAAAAATCTTCCTGATTCAGCGATTGATTTGCTTGA
TGAAGCAAGTGCAACGGTTCAAGGTTTGGTGAAAAAAGAAGCGCCAGCTACTTTGACACCTGCTGATAAAGCTATTTTGG
AAGGTGATTTCAAATTGGCAACGAAATTGCTGAAAGAGTCACGCAAGAAGCCAAATCGTAAACCAACTGCTGTGACAGAA
GATGATATTATGGCAACGCTCAGTCGTTTGTCAGGTATTCCTGTTGAGAAAATGACACAGGCAGATAGTAAGAAATACTT
GAACCTCGAAAAAGAATTCCATAAGCGTGTGATTGGCCAAGATTCAGCTATTTCAGCGATTAGTCGTGCTATTCGTCGTA
ATCAAGCGGGCATTCGTACAGGCAAACGTCCGATTGGCTCGTTTATGTTCTTGGGTCCAACGGGTGTTGGTAAAACAGAG
TTGGCTAAGGCACTAGCAGAATTGCTATTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTACATGGAAAA
ATTTGCGGCGAGCCGTCTTAACGGAGCTCCTCCAGGGTATGTCGGTTATGAAGAAGGTGGCGAATTGACTGAAAAAGTTC
GCAACAAACCTTATTCTGTGCTTCTATTTGATGAAATTGAAAAAGCCCACCCAGATATTTTCAATGTGCTTCTCCAAGTG
TTGGATGACGGTGTGCTGACGGATAGTCGTGGTCGTAAAGTTGATTTTTCAAACACGATTATTATCATGACATCAAATCT
TGGGGCAACCACTTTGCGTGATGAAAAGACAGTTGGTTTTGGTGCGCGTGATATGGCTCATGATTATGAGGCAATGCAAA
AACGCATCATGGAAGAACTCAAAAAAACTTACCGACCTGAATTCATCAACCGTATTGATGAAAAAGTTGTTTTCCACAAC
TTAACTCAAGAAAATATGCGTGATGTCGTGAAAATCATGGTTAAACCATTGATTGCGACACTAGCTGAAAAAGATATTAC
GCTAAAATTCCAACCATCAGCATTGAAATATTTAGCCGAAATTGGATACGACCCAGAAATGGGAGCTCGTCCGCTCCGCC
GTACTCTGCAAGATAAAGTTGAAGATGAATTATCAGAGCTTATTCTATCAGGCGAATTGGCAAGTGGAAATACCCTTAAA
ATCGGTGTTTCTAAAGGGCAACTCAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (235-366)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-134)

• AAA lid domain (AAA_lid_9) (374-452)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.601	99.877	0.765
clpC	Streptococcus thermophilus LMG 18311	73.252	100	0.734
clpC	Streptococcus thermophilus LMD-9	73.129	100	0.733
clpC	Streptococcus pneumoniae Rx1	67.319	100	0.677
clpC	Streptococcus pneumoniae D39	67.319	100	0.677
clpC	Streptococcus pneumoniae TIGR4	67.365	99.877	0.673
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.102	100	0.504
clpC	Bacillus subtilis subsp. subtilis str. 168	43.494	100	0.444