Detailed information NTG0798053

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: PY824_RS06275
• Genome accession: NZ_CP119172
• Coordinates: 1165902..1168010 (+)
• Length: 702 a.a.
• NCBI ID: WP_039670871.1
• Uniprot ID: A0AAP8FZZ0
• Organism: Streptococcus macedonicus strain SGM CIP105683
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1160902..1173010

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PY824_RS06260 (PY824_06260)	rplL	1163770..1164135 (-)	366	WP_014294676.1	50S ribosomal protein L7/L12	-
PY824_RS06265 (PY824_06265)	rplJ	1164215..1164718 (-)	504	WP_014294677.1	50S ribosomal protein L10	-
PY824_RS06270 (PY824_06270)	-	1165031..1165453 (+)	423	Protein_1168	helix-turn-helix domain-containing protein	-
PY824_RS06275 (PY824_06275)	clpC	1165902..1168010 (+)	2109	WP_039670871.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
PY824_RS06280 (PY824_06280)	-	1168117..1168764 (+)	648	Protein_1170	deoxyribonuclease I	-
PY824_RS06285 (PY824_06285)	-	1168873..1169499 (+)	627	WP_051673280.1	YoaK family protein	-
PY824_RS06290 (PY824_06290)	mmuM	1169584..1170531 (-)	948	WP_039670872.1	homocysteine S-methyltransferase	-
PY824_RS06295 (PY824_06295)	-	1170544..1171920 (-)	1377	WP_115266096.1	amino acid permease	-
PY824_RS06300 (PY824_06300)	yihA	1172219..1172812 (-)	594	WP_014294684.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 77388.30 Da
• Isoelectric Point: 4.7912

>NTDB_id=798053 PY824_RS06275 WP_039670871.1 1165902..1168010(+) (clpC) [Streptococcus macedonicus strain SGM CIP105683]
MANNNFYGRDPFGDMDDIFNRLMGNMGGYNSENRRYLINGREVTPEEFAQYRQTGKLPRNAEYQEGAPTSAPKEDGLLAK
LGTNLTERARANELDPVIGRNKEIQETAEVLSRRTKNNAVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDIS
GLEAGTQYRGAFEENIQNLIKEVKDAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAQDTFNILMGIRDLYEKHHNVILPDNVLKAAVDFSIQYIPQRSLPDKAIDLIDMTAAHL
AAQHPATDVKSLEKEIADQEEKLENAVAKEDYEAALSAKARIEELQKQIDNHTEGQKVTATVDDVAESVERLTGIPVSNM
GASDIERLKDLASRLKSKVIGQDKAVEAVSRAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDAIIR
LDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTIDFK
NTVIIATSNAGFGNEALTGQDDKDKKIMDRIAPYFRPEFLNRFDGIIEFSHLTKEDLKHIVDLMLDEVNKTIAKKGIDLV
VSDAAKQYLIEEGYDEAMGARPLRRVIEREIRDKITDFYLDHPDVKHLKADMVDGELVISEK

Nucleotide

• Length: 2109 bp

>NTDB_id=798053 PY824_RS06275 WP_039670871.1 1165902..1168010(+) (clpC) [Streptococcus macedonicus strain SGM CIP105683]
ATGGCAAATAATAATTTTTACGGAAGAGATCCTTTTGGAGATATGGATGACATTTTTAATAGACTTATGGGTAACATGGG
CGGCTACAATTCAGAAAACAGACGCTATTTGATTAATGGGCGCGAAGTTACTCCTGAAGAATTTGCACAATATCGCCAAA
CAGGTAAGCTTCCTAGAAACGCGGAATACCAAGAAGGGGCACCTACTTCTGCTCCTAAAGAAGATGGTCTCTTGGCAAAA
TTAGGAACAAACTTGACCGAACGCGCACGCGCTAACGAACTCGACCCTGTTATTGGACGTAACAAAGAAATCCAAGAAAC
TGCTGAAGTCTTGTCACGTCGTACCAAAAACAATGCTGTCCTTGTGGGGGATGCAGGTGTTGGTAAAACAGCCGTTGTCG
AAGGCTTAGCGCAAGCTATTGTCAATGGTGATGTGCCAGCAGCTATCAAAAATAAAGAAATTATTTCTATTGATATTTCT
GGTCTTGAAGCTGGCACACAATATCGTGGTGCTTTTGAAGAAAATATCCAAAACCTTATCAAGGAAGTTAAAGACGCTGG
TAATATCATTCTCTTCTTTGATGAAATCCACCAAATTTTAGGCGCAGGGTCAACTGGTGGCGACTCTGGTTCGAAAGGTT
TAGCTGATATTCTCAAACCTGCACTTTCTCGTGGCGAATTGACCGTTATCGGTGCAACAACTCAAGACGAATATCGTAAT
ACTATTTTGAAGAATGCTGCGCTTGCTCGCCGTTTCAACGAAGTCAAAGTAAATGCTCCTTCTGCTCAAGATACCTTTAA
TATTTTAATGGGAATTCGTGATTTATATGAGAAACACCACAACGTTATTCTCCCTGATAATGTGTTAAAAGCCGCTGTTG
ATTTTTCAATTCAATATATCCCACAACGTAGTTTACCAGATAAAGCTATTGACTTGATTGATATGACTGCTGCTCATTTG
GCTGCTCAACACCCTGCAACTGATGTCAAATCTCTTGAAAAGGAAATTGCAGACCAAGAAGAAAAACTAGAAAATGCTGT
GGCTAAAGAAGATTACGAGGCAGCTCTTAGTGCCAAGGCTCGTATCGAAGAATTGCAAAAACAAATTGATAACCATACGG
AAGGGCAAAAAGTTACAGCTACCGTTGATGATGTGGCAGAATCTGTCGAACGATTAACTGGTATTCCTGTGTCAAATATG
GGAGCAAGTGATATTGAACGCTTGAAAGATTTAGCTAGCCGTTTGAAAAGTAAAGTCATCGGACAAGATAAAGCTGTTGA
AGCCGTCTCACGTGCCATTCGTCGTAACCGTGCTGGTTTTGATGAAGGTAATCGACCAATTGGTAGTTTCCTCTTTGTCG
GTCCTACTGGCGTTGGTAAGACAGAGCTTGCTAAACAATTAGCCCTTGATATGTTCGGCTCAAAAGATGCTATTATCCGC
CTTGACATGTCTGAATACTCTGATCGCACAGCCGTTTCTAAATTAATCGGTACGACCGCTGGTTATGTTGGCTACGACGA
CAATAGCAACACGCTTACTGAACGTGTTCGTCGTAACCCATACTCAATTATTCTTCTTGATGAAATTGAAAAAGCTGACC
CTCAAGTCATCACACTTCTTCTCCAAGTTTTGGATGATGGTCGTTTGACAGACGGTCAAGGTAATACGATTGACTTTAAG
AATACCGTCATCATTGCTACCTCTAATGCTGGATTCGGCAACGAAGCTTTGACTGGTCAAGATGATAAAGATAAGAAAAT
TATGGATCGTATCGCTCCATACTTCCGCCCAGAATTTCTTAACCGTTTCGACGGTATTATCGAATTCTCTCACTTGACTA
AAGAAGATTTGAAACACATTGTTGACTTAATGCTTGACGAAGTTAACAAGACCATTGCCAAGAAAGGCATTGATTTGGTG
GTTAGTGATGCTGCTAAACAATACCTTATCGAAGAAGGTTATGATGAAGCCATGGGTGCTCGACCACTTCGCCGTGTCAT
TGAACGAGAAATCCGCGATAAAATCACTGATTTCTACCTCGATCACCCAGATGTTAAACACCTTAAAGCTGACATGGTTG
ACGGAGAACTAGTCATCAGCGAAAAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (261-355)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (612-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (120-252)

• AAA domain (Cdc48 subfamily) (AAA_2) (445-604)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	49.215	99.858	0.491
clpE	Streptococcus mutans UA159	50.549	90.741	0.459
clpE	Streptococcus pneumoniae TIGR4	49.921	90.456	0.452
clpE	Streptococcus pneumoniae Rx1	49.921	90.456	0.452
clpE	Streptococcus pneumoniae D39	49.921	90.456	0.452
clpE	Streptococcus pneumoniae R6	49.921	90.456	0.452
clpC	Bacillus subtilis subsp. subtilis str. 168	46.213	92.165	0.426
clpC	Streptococcus pneumoniae Rx1	43.86	89.316	0.392
clpC	Streptococcus pneumoniae D39	43.86	89.316	0.392
clpC	Streptococcus pneumoniae TIGR4	43.91	88.889	0.39
clpC	Streptococcus thermophilus LMD-9	44.032	88.319	0.389
clpC	Streptococcus thermophilus LMG 18311	43.851	88.034	0.386
clpC	Streptococcus mutans UA159	43.339	88.746	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.134	88.177	0.38