Detailed information NTG0797758

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: PXV46_RS14090
• Genome accession: NZ_CP119113
• Coordinates: 2803089..2803976 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GENOMIC22-002
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2798089..2808976

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PXV46_RS14060 (PXV46_14060)	-	2798098..2798190 (+)	93	WP_031774855.1	hypothetical protein	-
PXV46_RS14065 (PXV46_14065)	-	2798298..2798795 (-)	498	WP_001065267.1	glutathione peroxidase	-
PXV46_RS14070 (PXV46_14070)	-	2798805..2799065 (-)	261	WP_014937088.1	hypothetical protein	-
PXV46_RS14075 (PXV46_14075)	-	2799447..2799560 (-)	114	WP_014937089.1	hypothetical protein	-
PXV46_RS14080 (PXV46_14080)	-	2800229..2802229 (-)	2001	WP_000776741.1	ABC transporter permease	-
PXV46_RS14085 (PXV46_14085)	-	2802226..2802981 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
PXV46_RS14090 (PXV46_14090)	braS	2803089..2803976 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
PXV46_RS14095 (PXV46_14095)	braR	2803987..2804652 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
PXV46_RS14100 (PXV46_14100)	-	2804678..2804878 (-)	201	WP_000604731.1	hypothetical protein	-
PXV46_RS14105 (PXV46_14105)	-	2805076..2806500 (+)	1425	WP_021286019.1	alkaline phosphatase	-
PXV46_RS14110 (PXV46_14110)	-	2806570..2806680 (+)	111	WP_001791296.1	hypothetical protein	-
PXV46_RS14115 (PXV46_14115)	-	2806783..2807238 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
PXV46_RS14120 (PXV46_14120)	-	2807482..2808243 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=797758 PXV46_RS14090 WP_000143420.1 2803089..2803976(-) (braS) [Staphylococcus aureus strain GENOMIC22-002]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=797758 PXV46_RS14090 WP_000143420.1 2803089..2803976(-) (braS) [Staphylococcus aureus strain GENOMIC22-002]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993