Detailed information NTG0797673

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: PXV45_RS00950
• Genome accession: NZ_CP119109
• Coordinates: 207131..208018 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GENOMIC22-001
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 202131..213018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PXV45_RS00920 (PXV45_00920)	-	202864..203625 (+)	762	WP_000323448.1	alpha/beta hydrolase family protein	-
PXV45_RS00925 (PXV45_00925)	-	203869..204324 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
PXV45_RS00930 (PXV45_00930)	-	204446..204547 (+)	102	WP_000731972.1	SE2200 family small protein	-
PXV45_RS00935 (PXV45_00935)	-	204607..206031 (-)	1425	WP_000953736.1	alkaline phosphatase	-
PXV45_RS00940 (PXV45_00940)	-	206229..206429 (+)	201	WP_000604731.1	hypothetical protein	-
PXV45_RS00945 (PXV45_00945)	braR	206455..207120 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
PXV45_RS00950 (PXV45_00950)	braS	207131..208018 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
PXV45_RS00955 (PXV45_00955)	-	208126..208881 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
PXV45_RS00960 (PXV45_00960)	-	208878..210878 (+)	2001	WP_000776741.1	ABC transporter permease	-
PXV45_RS00965 (PXV45_00965)	-	211547..211660 (+)	114	WP_014937089.1	hypothetical protein	-
PXV45_RS00970 (PXV45_00970)	-	212042..212302 (+)	261	WP_014937088.1	hypothetical protein	-
PXV45_RS00975 (PXV45_00975)	-	212312..212809 (+)	498	WP_001065267.1	glutathione peroxidase	-
PXV45_RS00980 (PXV45_00980)	-	212917..213009 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=797673 PXV45_RS00950 WP_000143420.1 207131..208018(+) (braS) [Staphylococcus aureus strain GENOMIC22-001]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=797673 PXV45_RS00950 WP_000143420.1 207131..208018(+) (braS) [Staphylococcus aureus strain GENOMIC22-001]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993