Detailed information NTG0797138

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYW44_RS04830
• Genome accession: NZ_CP118982
• Coordinates: 1017918..1018961 (+)
• Length: 347 a.a.
• NCBI ID: WP_002511392.1
• Uniprot ID: A0A9X4QYU5
• Organism: Staphylococcus equorum strain DSM 20674
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1012918..1023961

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYW44_RS04805	-	1013975..1014694 (+)	720	WP_002507200.1	type 1 glutamine amidotransferase	-
PYW44_RS04810	-	1014793..1015779 (-)	987	WP_021339816.1	FUSC family protein	-
PYW44_RS04815	map	1015960..1016712 (+)	753	WP_002507202.1	type I methionyl aminopeptidase	-
PYW44_RS04820	-	1016817..1017203 (+)	387	WP_002507203.1	hypothetical protein	-
PYW44_RS04825	liaF	1017220..1017921 (+)	702	WP_002507204.1	cell wall-active antibiotics response protein LiaF	-
PYW44_RS04830	vraS	1017918..1018961 (+)	1044	WP_002511392.1	sensor histidine kinase	Regulator
PYW44_RS04835	vraR	1018951..1019580 (+)	630	WP_002507206.1	response regulator transcription factor	Regulator
PYW44_RS04840	-	1019776..1020942 (-)	1167	WP_002511391.1	YihY/virulence factor BrkB family protein	-
PYW44_RS04845	-	1021173..1021457 (-)	285	WP_002507208.1	hypothetical protein	-
PYW44_RS04850	-	1021464..1021928 (-)	465	WP_002507209.1	low molecular weight protein-tyrosine-phosphatase	-
PYW44_RS04855	-	1022084..1022266 (+)	183	WP_226956897.1	DUF1128 family protein	-
PYW44_RS04860	-	1022282..1023520 (+)	1239	WP_064782814.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39973.32 Da
• Isoelectric Point: 5.8180

>NTDB_id=797138 PYW44_RS04830 WP_002511392.1 1017918..1018961(+) (vraS) [Staphylococcus equorum strain DSM 20674]
MNHYIRAIGSMLILVYSTFFALFFIDKVFVNIVYFQGMFYTQIFGIPVLLFLNLLVIFLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEAPLDQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLKKKVPMKVVHDI
EEFEVPKGIEDHLFRITQEALSNTLRHSKGTKVTVELFNMADYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSHDD

Nucleotide

• Length: 1044 bp

>NTDB_id=797138 PYW44_RS04830 WP_002511392.1 1017918..1018961(+) (vraS) [Staphylococcus equorum strain DSM 20674]
ATGAATCACTACATAAGAGCAATAGGATCCATGTTGATATTAGTTTATAGCACATTTTTTGCTCTGTTTTTTATCGATAA
AGTATTTGTAAACATAGTATATTTTCAAGGTATGTTTTATACACAAATTTTTGGAATACCAGTTTTACTATTTTTAAACT
TATTAGTTATTTTTCTTTGTATTATTGTAGGATCGGTATTAGCATATAAAATAAATCAACAAAATCACTGGTTACAAGAC
CAAATAGAACGTTCTATTGAAGGTCAAACAGTAGGTATTAATGATCAAAACATTGAATTATATAATGAAACAATTGAATT
GTATCAAACGTTAGTTCCATTAAATCAAGAAGTTCACAAATTACGTATGAAAACGCAAAACTTAACAAATGAATCATATA
ATATAAATGATGTGAAAGTTAAAAAGATTATAGAAGATGAACGACAAAGGCTTGCACGTGAATTACACGATTCAGTAAGT
CAGCAATTATTTGCAGCGAGTATGATGCTTTCAGCTATTAAAGAAACACAGTTAGAAGCACCTTTAGATCAACAAATTCC
GATATTAGAAAAAATGGTACAAGATTCTCAGTTAGAGATGAGAGCTTTACTATTACATTTAAGACCTATTGGATTAAAAG
ACAAATCATTAGGTGAAGGTATTAAAGATTTAGTCGTTGATTTAAAGAAAAAAGTACCTATGAAAGTTGTACATGATATT
GAAGAATTTGAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACGCAAGAAGCTTTATCTAATACTTTGAGACA
TTCAAAAGGTACCAAAGTAACAGTAGAATTGTTTAATATGGCAGATTACTTATTATTACGCATTCAAGACAATGGTAAAG
GGTTCAATGTTGATGATAAGGTAGAACAAAGTTATGGTTTAAAAAACATGAGAGAACGTGCGCTTGAAATTGGTGCAACG
TTTCATATTGTTTCTTTACCAGATTCAGGTACAAGAATTGAAGTAAAGGCACCATTAAATAAGGAGGATTCACATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.184	100	0.882