Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   PYW37_RS12165 Genome accession   NZ_CP118969
Coordinates   2386781..2387809 (-) Length   342 a.a.
NCBI ID   WP_023190255.1    Uniprot ID   A0AAW7IXD6
Organism   Lactococcus lactis strain DSM 20481     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2381781..2392809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYW37_RS12145 - 2382855..2383712 (-) 858 WP_023190258.1 Rgg/GadR/MutR family transcriptional regulator -
  PYW37_RS12150 - 2383823..2384962 (-) 1140 WP_044009594.1 MFS transporter -
  PYW37_RS12155 kwcM 2384959..2386278 (-) 1320 WP_025017142.1 KxxxW cyclic peptide radical SAM maturase -
  PYW37_RS12160 - 2386346..2386459 (-) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  PYW37_RS12165 sepM 2386781..2387809 (-) 1029 WP_023190255.1 SepM family pheromone-processing serine protease Regulator
  PYW37_RS12170 coaD 2387796..2388293 (-) 498 WP_025017143.1 pantetheine-phosphate adenylyltransferase -
  PYW37_RS12175 rsmD 2388341..2388880 (-) 540 WP_023190253.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  PYW37_RS12180 - 2389051..2390271 (-) 1221 WP_003132654.1 MFS transporter -
  PYW37_RS12185 lmrP 2390353..2391579 (-) 1227 WP_025017145.1 multidrug efflux MFS transporter LmrP -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37296.91 Da        Isoelectric Point: 9.8043

>NTDB_id=796983 PYW37_RS12165 WP_023190255.1 2386781..2387809(-) (sepM) [Lactococcus lactis strain DSM 20481]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGCEIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=796983 PYW37_RS12165 WP_023190255.1 2386781..2387809(-) (sepM) [Lactococcus lactis strain DSM 20481]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGTAAAACAGGAATTGGGA
TTAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCGAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTTGCGAAATTGCTGGAACTGG
GACGATTGAACACGACGGAAGCATTGGTCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGTAAAGAAGGGGCAA
AAGTCTTCTTAGTGCCTGATTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.406

100

0.488