Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   PYW30_RS02415 Genome accession   NZ_CP118950
Coordinates   481314..482804 (+) Length   496 a.a.
NCBI ID   WP_042217260.1    Uniprot ID   A0A1I4FU19
Organism   Lactococcus garvieae subsp. garvieae strain DSM 20684     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 476314..487804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYW30_RS02390 pfkB 476461..477387 (+) 927 WP_042217267.1 1-phosphofructokinase -
  PYW30_RS02395 - 477402..479306 (+) 1905 WP_014024348.1 fructose-specific PTS transporter subunit EIIC -
  PYW30_RS02400 - 479418..479660 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  PYW30_RS02405 - 479877..480428 (+) 552 WP_023889673.1 YceD family protein -
  PYW30_RS02410 covR 480530..481225 (+) 696 WP_004259096.1 response regulator transcription factor Regulator
  PYW30_RS02415 covS 481314..482804 (+) 1491 WP_042217260.1 HAMP domain-containing histidine kinase Regulator
  PYW30_RS02420 - 483201..484772 (+) 1572 WP_042217258.1 ABC transporter permease subunit -
  PYW30_RS02425 - 484773..485510 (+) 738 WP_042217256.1 amino acid ABC transporter ATP-binding protein -
  PYW30_RS02430 murD 485649..487010 (+) 1362 WP_004259085.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56767.76 Da        Isoelectric Point: 5.1990

>NTDB_id=796685 PYW30_RS02415 WP_042217260.1 481314..482804(+) (covS) [Lactococcus garvieae subsp. garvieae strain DSM 20684]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGEVSVTS
VVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=796685 PYW30_RS02415 WP_042217260.1 481314..482804(+) (covS) [Lactococcus garvieae subsp. garvieae strain DSM 20684]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTCCGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTATCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGTAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCTC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTG
GAACGACCGGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTACAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCTTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTGGAACGGTTGCACGATGCGATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCCGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACAATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATCGATTTTCAAGATGAAGACCTTATCTG
TGATCCGACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATTCATGCTGATTTAAGCTTAACTGTGGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTACCCGAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCTATA
AAATATTCGCCTAAAGATCGCCAAGAAGTGAAAATTCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTATGATGGGGAGGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAG

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(214-266)

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

ArlS sensor domain (ArlS_N)

(52-190)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FU19

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

56.137

100

0.563