Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   PYH53_RS10075 Genome accession   NZ_CP118860
Coordinates   2029634..2030350 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 7075     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2024634..2035350
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYH53_RS10045 (PYH53_10045) - 2024849..2025475 (+) 627 WP_000522384.1 nitroreductase family protein -
  PYH53_RS10050 (PYH53_10050) - 2025836..2026621 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  PYH53_RS10055 (PYH53_10055) - 2027221..2027355 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  PYH53_RS10060 (PYH53_10060) - 2027591..2028154 (+) 564 WP_001105704.1 accessory gene regulator AgrB -
  PYH53_RS10065 (PYH53_10065) agrD 2028158..2028298 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  PYH53_RS10070 (PYH53_10070) agrC 2028323..2029615 (+) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  PYH53_RS10075 (PYH53_10075) agrA 2029634..2030350 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  PYH53_RS10080 (PYH53_10080) - 2030422..2030531 (+) 110 Protein_1948 hypothetical protein -
  PYH53_RS10085 (PYH53_10085) - 2030719..2031678 (-) 960 WP_001253293.1 carbohydrate kinase -
  PYH53_RS10090 (PYH53_10090) - 2031675..2033159 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  PYH53_RS10095 (PYH53_10095) - 2033308..2034258 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=795941 PYH53_RS10075 WP_000688498.1 2029634..2030350(+) (agrA) [Staphylococcus aureus strain 7075]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=795941 PYH53_RS10075 WP_000688498.1 2029634..2030350(+) (agrA) [Staphylococcus aureus strain 7075]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996