Detailed information    

insolico Bioinformatically predicted

Overview

Name   rec2   Type   Machinery gene
Locus tag   HIY_RS05685 Genome accession   NZ_AP022867
Coordinates   1101624..1103990 (+) Length   788 a.a.
NCBI ID   WP_005657747.1    Uniprot ID   A0A0H3PCV2
Organism   Haemophilus influenzae strain 2018-Y40     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1096624..1108990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIY_RS05660 (HIY_10860) - 1096972..1098270 (-) 1299 WP_005657733.1 N-acetylmuramoyl-L-alanine amidase -
  HIY_RS05665 (HIY_10870) tsaE 1098278..1098754 (-) 477 WP_005657736.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  HIY_RS05670 (HIY_10880) folK 1098830..1099312 (-) 483 WP_005657739.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
  HIY_RS05675 (HIY_10890) pcnB 1099321..1100679 (-) 1359 WP_005657742.1 polynucleotide adenylyltransferase PcnB -
  HIY_RS05680 (HIY_10900) dksA 1100927..1101364 (-) 438 WP_005657744.1 RNA polymerase-binding protein DksA -
  HIY_RS05685 (HIY_10910) rec2 1101624..1103990 (+) 2367 WP_005657747.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  HIY_RS05690 (HIY_10920) msbA 1104031..1105794 (+) 1764 WP_005657750.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  HIY_RS05695 (HIY_10930) lpxK 1105867..1106865 (+) 999 WP_005657751.1 tetraacyldisaccharide 4'-kinase -
  HIY_RS05700 (HIY_10940) kdsB 1106936..1107700 (+) 765 WP_005657753.1 3-deoxy-manno-octulosonate cytidylyltransferase -

Sequence

Protein


Download         Length: 788 a.a.        Molecular weight: 89341.04 Da        Isoelectric Point: 10.0762

>NTDB_id=79572 HIY_RS05685 WP_005657747.1 1101624..1103990(+) (rec2) [Haemophilus influenzae strain 2018-Y40]
MKLNLITLAVLLIVADLTLLFLPQPLLLPWQVALVIALVLIFLFIFLRRNFLVSLAFFVASLGYFHYSALSLLQQAQNIT
AQKQVVTFKIQEILHQQDYQTLIATATLANNLQEQRIFLNWKAKEVPQLSEIWQAEISLRPLSARLNFGGFDRQQWYFSK
GITVVGTVKSAVKIADVSSLRAEKLQQVKKQTEGLSLQGLLIALAFGERAWLDKTTWSIYQQTNTAHLIAISGLHIGLAM
GIGFCLVRVMQVFLPTRFIHPYFPLVFGVLLALIYAYLAGFSVPTFRAISALVFVLFIQIMRRHYSPIQLFTVVVGFLLF
CNPLMPLSVSFWLSCGAVGCLILWYRYVPFSLFQWKNRPFSPKVRWILSLFHLQFGLLLFFTPLQLFLFNGLSLSGFLAN
LMAVPIYSFLLVPLILFAVFTNGTMFSWQLANKLAEGITGLISVFQGNWLTVSFNLALFLTALCAGIFMLIIWRIYREPE
ASSSTWKIKRPRFFTLNLSKPLLKNDRINVLRCSFGIILLCFTILLFKQFSKPAWQVDTLDVGQGLATLIVKNGKGILYD
TGSSWRGGSMAELEILPYLQREGIVLEKLILSHDDNDHAGGASTILKAYPNVELITPSRKNYGENYRTFCTAGRDWHWQG
LHFQILSPHNVVTRADNPHSCVILVDDGKNSVLLTGDAEAKNEQIFARTLGKIDVLQVGHHGSKTSTSEYLLSQVRPDVA
IISSGRWNPWKFPHYSVMERLHRYKSAVENTAVSGQVRVNFFKDRLEIQQARTEFSPWYARVIGLSKE

Nucleotide


Download         Length: 2367 bp        

>NTDB_id=79572 HIY_RS05685 WP_005657747.1 1101624..1103990(+) (rec2) [Haemophilus influenzae strain 2018-Y40]
ATGAAATTAAACTTAATAACTTTAGCTGTCTTGTTAATTGTCGCGGATTTAACGTTGTTATTTCTACCGCAACCGTTGCT
ATTGCCTTGGCAAGTTGCTCTCGTTATTGCGCTTGTTTTGATTTTTCTTTTTATTTTCTTGCGTAGAAATTTCTTAGTTA
GCCTTGCTTTTTTTGTTGCCTCTCTTGGCTATTTTCATTATTCGGCTTTGAGTTTATTACAACAAGCTCAAAATATTACC
GCTCAAAAGCAAGTGGTAACTTTTAAGATTCAAGAAATTTTGCACCAACAGGATTATCAAACGCTTATCGCCACAGCAAC
ATTGGCGAATAATTTGCAAGAACAACGAATTTTCTTAAATTGGAAAGCGAAAGAGGTGCCTCAATTATCGGAAATTTGGC
AAGCTGAAATTTCTTTACGTCCCCTTTCTGCACGATTAAATTTTGGTGGGTTTGATCGGCAACAATGGTATTTTTCAAAA
GGAATTACTGTTGTTGGAACGGTAAAAAGTGCGGTGAAAATTGCGGATGTTTCATCATTGCGTGCAGAAAAATTGCAACA
AGTAAAGAAGCAAACGGAAGGATTATCTCTACAAGGTTTATTGATTGCCTTAGCTTTTGGCGAACGGGCTTGGTTAGATA
AAACCACTTGGTCAATTTACCAACAAACCAATACCGCACATCTTATTGCTATTTCTGGCTTACATATTGGGTTGGCTATG
GGAATTGGATTTTGCTTGGTGCGTGTTATGCAAGTATTTTTACCCACCCGTTTTATTCATCCTTATTTTCCTTTAGTTTT
TGGTGTTTTATTGGCTTTAATTTATGCGTATTTGGCTGGTTTTAGCGTGCCAACTTTTCGTGCCATTTCAGCACTTGTTT
TCGTTTTATTTATTCAAATAATGAGGCGACATTATTCGCCCATTCAGCTTTTTACGGTGGTTGTCGGATTCTTGCTTTTC
TGCAATCCATTAATGCCGCTTTCGGTCAGTTTTTGGCTTTCTTGTGGGGCGGTTGGGTGTTTGATCCTCTGGTATCGTTA
TGTGCCTTTTTCTCTTTTTCAATGGAAAAATCGCCCCTTTTCACCAAAAGTGCGGTGGATTTTGAGTTTATTTCATTTGC
AATTTGGGTTATTGCTCTTTTTTACACCTTTGCAACTTTTTCTATTTAATGGCTTATCGTTGAGTGGATTTTTAGCCAAT
CTTATGGCGGTTCCAATTTATAGTTTTTTGCTTGTGCCATTAATTTTATTTGCCGTTTTTACTAACGGCACAATGTTTTC
TTGGCAACTAGCAAACAAGTTAGCCGAAGGAATTACTGGGTTAATTTCTGTTTTTCAAGGAAATTGGCTCACGGTTTCAT
TTAATTTAGCATTATTTTTAACCGCACTTTGTGCAGGAATTTTTATGTTAATTATTTGGCGTATTTATCGAGAACCAGAG
GCTTCATCATCAACTTGGAAAATTAAACGACCAAGATTTTTTACATTAAATCTCAGTAAACCTTTGCTAAAAAATGATCG
AATCAACGTTTTGCGATGTTCTTTCGGCATTATCTTACTGTGTTTTACGATTTTGTTGTTTAAACAATTTAGTAAGCCAG
CTTGGCAGGTAGATACTTTAGATGTGGGGCAGGGCTTGGCAACGCTGATTGTGAAAAATGGCAAAGGGATTCTTTATGAT
ACGGGTTCTTCTTGGCGAGGTGGAAGTATGGCTGAGTTGGAAATTTTGCCTTATTTACAAAGAGAAGGGATTGTTTTGGA
AAAATTGATTTTAAGCCACGACGATAACGATCACGCAGGTGGTGCTTCGACAATTTTAAAGGCGTATCCCAATGTGGAAT
TGATTACCCCTTCACGGAAAAACTATGGGGAAAATTACCGCACTTTTTGTACTGCTGGGCGTGATTGGCATTGGCAAGGG
TTGCATTTTCAAATACTTTCTCCTCACAATGTTGTGACACGAGCTGATAATCCCCATTCTTGTGTGATTTTAGTCGATGA
TGGAAAGAATAGTGTTTTGCTAACTGGCGATGCTGAAGCAAAAAATGAGCAAATTTTTGCCCGCACTTTAGGCAAAATCG
ATGTGTTGCAAGTGGGGCATCATGGGAGTAAAACATCGACAAGTGAATACTTGCTTTCTCAGGTTAGACCAGATGTAGCG
ATTATTTCTAGTGGGCGTTGGAATCCGTGGAAATTCCCTCATTATTCGGTTATGGAAAGGCTTCATCGCTATAAAAGTGC
GGTAGAAAATACCGCTGTTTCAGGGCAAGTGCGGGTAAATTTTTTTAAAGACCGATTAGAAATCCAACAAGCACGCACAG
AATTTTCCCCTTGGTATGCGCGTGTAATTGGATTATCAAAGGAATAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(204-473)

Domain of unknown function (DUF4131) (DUF4131)

(28-171)

Metallo-beta-lactamase superfamily (Lactamase_B)

(541-725)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3PCV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rec2 Haemophilus influenzae Rd KW20

96.447

100

0.964

Multiple sequence alignment