Detailed information NTG0795694

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYH65_RS09625
• Genome accession: NZ_CP118832
• Coordinates: 1963394..1964437 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 7053
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1958394..1969437

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH65_RS09595 (PYH65_09600)	-	1958816..1960072 (-)	1257	WP_001793428.1	aminopeptidase	-
PYH65_RS09600 (PYH65_09605)	-	1960075..1960275 (-)	201	WP_000180460.1	DUF1128 family protein	-
PYH65_RS09605 (PYH65_09610)	-	1960422..1960886 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
PYH65_RS09610 (PYH65_09615)	-	1960893..1961168 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
PYH65_RS09615 (PYH65_09620)	-	1961446..1962663 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
PYH65_RS09620 (PYH65_09625)	vraR	1962775..1963404 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
PYH65_RS09625 (PYH65_09630)	vraS	1963394..1964437 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
PYH65_RS09630 (PYH65_09635)	liaF	1964434..1965135 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
PYH65_RS09635 (PYH65_09640)	-	1965150..1965536 (-)	387	WP_001110179.1	hypothetical protein	-
PYH65_RS09640 (PYH65_09645)	map	1965753..1966511 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
PYH65_RS09645 (PYH65_09650)	-	1967042..1968028 (+)	987	WP_000999716.1	aromatic acid exporter family protein	-
PYH65_RS09650 (PYH65_09655)	-	1968518..1968931 (-)	414	WP_001670387.1	hypothetical protein	-
PYH65_RS09655 (PYH65_09660)	-	1968960..1969070 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=795694 PYH65_RS09625 WP_001017131.1 1963394..1964437(-) (vraS) [Staphylococcus aureus strain 7053]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=795694 PYH65_RS09625 WP_001017131.1 1963394..1964437(-) (vraS) [Staphylococcus aureus strain 7053]
ATGAACCATTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1