Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   PYH74_RS06145 Genome accession   NZ_CP118814
Coordinates   1280325..1281392 (+) Length   355 a.a.
NCBI ID   WP_001831131.1    Uniprot ID   A0A9Q5JLH5
Organism   Staphylococcus epidermidis strain 7060     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1275325..1286392
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYH74_RS06115 (PYH74_06115) - 1275414..1276037 (+) 624 WP_001831016.1 MBL fold metallo-hydrolase -
  PYH74_RS06120 (PYH74_06120) - 1276094..1276657 (+) 564 Protein_1165 ATPase, T2SS/T4P/T4SS family -
  PYH74_RS06125 (PYH74_06125) - 1276835..1277131 (+) 297 WP_002311824.1 hypothetical protein -
  PYH74_RS06130 (PYH74_06130) - 1277138..1279090 (+) 1953 WP_000163792.1 hypothetical protein -
  PYH74_RS06135 (PYH74_06135) dfrG 1279162..1279659 (-) 498 WP_000868795.1 trimethoprim-resistant dihydrofolate reductase DfrG -
  PYH74_RS06140 (PYH74_06140) - 1279934..1280353 (+) 420 Protein_1169 ATPase, T2SS/T4P/T4SS family -
  PYH74_RS06145 (PYH74_06145) comGB 1280325..1281392 (+) 1068 WP_001831131.1 competence type IV pilus assembly protein ComGB Machinery gene
  PYH74_RS06150 (PYH74_06150) comGC 1281410..1281727 (+) 318 WP_001831271.1 competence type IV pilus major pilin ComGC Machinery gene
  PYH74_RS06155 (PYH74_06155) comGD 1281717..1282154 (+) 438 WP_001831025.1 competence type IV pilus minor pilin ComGD -
  PYH74_RS06160 (PYH74_06160) - 1282141..1282434 (+) 294 WP_001831116.1 hypothetical protein -
  PYH74_RS06165 (PYH74_06165) - 1282358..1282879 (+) 522 WP_282888210.1 competence type IV pilus minor pilin ComGF -
  PYH74_RS06170 (PYH74_06170) - 1283015..1283527 (+) 513 WP_002440040.1 shikimate kinase -
  PYH74_RS06175 (PYH74_06175) gcvT 1283745..1284836 (+) 1092 WP_001831107.1 glycine cleavage system aminomethyltransferase GcvT -
  PYH74_RS06180 (PYH74_06180) gcvPA 1284856..1286202 (+) 1347 WP_002456181.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 355 a.a.        Molecular weight: 42379.68 Da        Isoelectric Point: 10.1702

>NTDB_id=795535 PYH74_RS06145 WP_001831131.1 1280325..1281392(+) (comGB) [Staphylococcus epidermidis strain 7060]
MKKLSINTFKYKRNKYLTEIQSIDLLQRLQQLLSHGFTLYQSFKFLNSYFKYKERTINKKIIQHLQNGATCYDILKIIGY
PELVLLQIKFAENYGNIEEALVDTVQYMKRNLKAKKRLIKTLQYPVALISIFLFILTILNITVIPQFQQLYETMNVKLST
FQNLLTLIITRLPKLTFIFIFISGIAFFITYKFYYYLPIEKKLKSILKIPMINTYYKIYRTYQLSNQLSLFYRNGTSLQQ
IVRIYRNEQDNDFLKFLGDYLFKEANKGLPLPVILMNLKCFQNDLIKFIEQGEKNGKLDIELKLYSQMLLQQFEEKVLKQ
TKFIQPIIFFILGIFIVSLYLVIMLPMFELMQTIK

Nucleotide


Download         Length: 1068 bp        

>NTDB_id=795535 PYH74_RS06145 WP_001831131.1 1280325..1281392(+) (comGB) [Staphylococcus epidermidis strain 7060]
GTGAAGAAGTTGTCGATAAATACATTTAAATATAAGAGGAATAAATATCTTACTGAAATACAATCAATAGACTTACTACA
GAGATTACAACAGCTTTTAAGTCACGGATTCACTTTATATCAAAGTTTTAAATTTTTAAACTCCTATTTTAAATATAAAG
AGCGAACAATAAATAAAAAGATTATCCAACATCTACAAAACGGTGCTACATGTTATGATATTTTAAAAATAATAGGGTAT
CCAGAATTAGTTCTTCTTCAAATAAAATTTGCTGAAAACTACGGCAACATTGAGGAGGCTCTCGTTGATACTGTTCAATA
TATGAAAAGAAATCTGAAAGCTAAAAAACGACTCATCAAAACCTTACAATATCCTGTTGCATTAATTTCTATCTTCTTAT
TCATATTAACCATTTTAAATATAACTGTCATACCTCAATTTCAACAACTTTATGAGACTATGAATGTTAAATTATCAACA
TTTCAAAATCTACTAACTCTTATTATTACCCGTCTTCCCAAACTAACTTTCATTTTTATCTTTATTAGTGGTATAGCATT
TTTTATCACTTATAAATTCTACTATTATCTACCAATTGAGAAAAAGTTAAAATCTATTTTAAAAATCCCAATGATTAATA
CGTATTATAAAATATATAGAACTTATCAACTTTCCAATCAACTTTCTTTATTTTACAGAAATGGTACAAGTCTTCAACAA
ATTGTCCGTATATATCGTAATGAGCAAGATAACGATTTTCTTAAATTTCTGGGTGATTATCTTTTTAAAGAAGCTAATAA
AGGGCTCCCGTTACCTGTTATATTAATGAATTTAAAATGTTTTCAAAATGATTTGATTAAATTCATAGAACAAGGAGAGA
AAAATGGGAAATTAGATATAGAATTAAAGTTATACAGTCAAATGCTATTACAGCAATTTGAAGAAAAAGTGTTAAAACAA
ACAAAATTTATACAACCTATCATCTTCTTTATCTTGGGAATTTTTATTGTATCTTTATACTTAGTCATTATGCTTCCTAT
GTTTGAACTTATGCAAACAATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(225-346)

Type II secretion system (T2SS), protein F (T2SSF)

(26-145)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

49.719

100

0.499
  comGB Staphylococcus aureus N315

49.719

100

0.499