Detailed information NTG0795481

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: PYH57_RS13960
• Genome accession: NZ_CP118810
• Coordinates: 2767580..2768467 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 7062
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2762580..2773467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH57_RS13930 (PYH57_13920)	-	2762582..2762674 (+)	93	WP_010956583.1	hypothetical protein	-
PYH57_RS13935 (PYH57_13925)	-	2762782..2763279 (-)	498	WP_250426068.1	glutathione peroxidase	-
PYH57_RS13940 (PYH57_13930)	-	2763289..2763549 (-)	261	WP_078064828.1	hypothetical protein	-
PYH57_RS13945 (PYH57_13935)	-	2763931..2764044 (-)	114	WP_072491147.1	hypothetical protein	-
PYH57_RS13950 (PYH57_13940)	-	2764720..2766720 (-)	2001	WP_353459065.1	ABC transporter permease	-
PYH57_RS13955 (PYH57_13945)	-	2766717..2767472 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
PYH57_RS13960 (PYH57_13950)	braS	2767580..2768467 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
PYH57_RS13965 (PYH57_13955)	braR	2768478..2769143 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
PYH57_RS13970 (PYH57_13960)	-	2769169..2769369 (-)	201	WP_353459067.1	hypothetical protein	-
PYH57_RS13975 (PYH57_13965)	-	2769567..2770991 (+)	1425	WP_000953759.1	alkaline phosphatase	-
PYH57_RS13980	-	2771051..2771152 (-)	102	WP_000731972.1	SE2200 family small protein	-
PYH57_RS13985 (PYH57_13975)	-	2771274..2771729 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
PYH57_RS13990 (PYH57_13980)	-	2771974..2772735 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=795481 PYH57_RS13960 WP_000143420.1 2767580..2768467(-) (braS) [Staphylococcus aureus strain 7062]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=795481 PYH57_RS13960 WP_000143420.1 2767580..2768467(-) (braS) [Staphylococcus aureus strain 7062]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993