Detailed information NTG0795282

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYH70_RS04525
• Genome accession: NZ_CP118789
• Coordinates: 930745..931788 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain 7068
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 925745..936788

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH70_RS04500 (PYH70_04505)	-	926801..927526 (+)	726	WP_002466154.1	type 1 glutamine amidotransferase	-
PYH70_RS04505 (PYH70_04510)	-	927594..928580 (-)	987	WP_031464159.1	aromatic acid exporter family protein	-
PYH70_RS04510 (PYH70_04515)	map	928747..929502 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
PYH70_RS04515 (PYH70_04520)	-	929646..930032 (+)	387	WP_002466133.1	DUF2543 family protein	-
PYH70_RS04520 (PYH70_04525)	liaF	930047..930748 (+)	702	WP_002466140.1	cell wall-active antibiotics response protein LiaF	-
PYH70_RS04525 (PYH70_04530)	vraS	930745..931788 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
PYH70_RS04530 (PYH70_04535)	vraR	931778..932407 (+)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
PYH70_RS04535 (PYH70_04540)	-	932466..933701 (-)	1236	WP_002466159.1	YihY/virulence factor BrkB family protein	-
PYH70_RS04540 (PYH70_04545)	-	933931..934215 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
PYH70_RS04545 (PYH70_04550)	-	934222..934686 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
PYH70_RS04550 (PYH70_04555)	-	934833..935036 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
PYH70_RS04555 (PYH70_04560)	-	935049..936290 (+)	1242	WP_353422431.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=795282 PYH70_RS04525 WP_002466111.1 930745..931788(+) (vraS) [Staphylococcus warneri strain 7068]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=795282 PYH70_RS04525 WP_002466111.1 930745..931788(+) (vraS) [Staphylococcus warneri strain 7068]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTCCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948