Detailed information NTG0795216

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYH71_RS04670
• Genome accession: NZ_CP118786
• Coordinates: 1026789..1027832 (+)
• Length: 347 a.a.
• NCBI ID: WP_019166463.1
• Uniprot ID: A0A2A4GVQ0
• Organism: Staphylococcus delphini strain 7071
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1021789..1032832

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH71_RS04645 (PYH71_04640)	-	1022854..1023579 (+)	726	WP_019166458.1	glutamine amidotransferase	-
PYH71_RS04650 (PYH71_04645)	-	1023735..1024733 (-)	999	WP_096542445.1	aromatic acid exporter family protein	-
PYH71_RS04655 (PYH71_04650)	map	1024830..1025591 (+)	762	WP_019166460.1	type I methionyl aminopeptidase	-
PYH71_RS04660 (PYH71_04655)	-	1025689..1026078 (+)	390	WP_096542447.1	hypothetical protein	-
PYH71_RS04665 (PYH71_04660)	liaF	1026091..1026792 (+)	702	WP_096557032.1	cell wall-active antibiotics response protein LiaF	-
PYH71_RS04670 (PYH71_04665)	vraS	1026789..1027832 (+)	1044	WP_019166463.1	sensor histidine kinase	Regulator
PYH71_RS04675 (PYH71_04670)	vraR	1027822..1028451 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
PYH71_RS04680 (PYH71_04675)	-	1028606..1029187 (-)	582	WP_096557031.1	carbonic anhydrase	-
PYH71_RS04685 (PYH71_04680)	-	1029220..1030566 (-)	1347	WP_096557029.1	YihY/virulence factor BrkB family protein	-
PYH71_RS04690 (PYH71_04685)	-	1030782..1031069 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
PYH71_RS04695 (PYH71_04690)	-	1031077..1031535 (-)	459	WP_353418617.1	low molecular weight protein-tyrosine-phosphatase	-
PYH71_RS04700 (PYH71_04695)	-	1031669..1031872 (+)	204	WP_019166467.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39911.18 Da
• Isoelectric Point: 5.0397

>NTDB_id=795216 PYH71_RS04670 WP_019166463.1 1026789..1027832(+) (vraS) [Staphylococcus delphini strain 7071]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWVKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=795216 PYH71_RS04670 WP_019166463.1 1026789..1027832(+) (vraS) [Staphylococcus delphini strain 7071]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATCGATAA
AGTGTTTACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGGATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATCGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGGTGAAGCAA
CAAATCGTTCGTGCTTTCGAAGGCGAAACAGTGGGAATCAATGATCAACAACTTGAGCTGTACAATGAAACGATTGAATT
GTACCAAGCGCTCGTCCCATTGAATCAAGAACTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATTGAAGATGAACGGCAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAGGAAACAGATTTAGCTCCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCACTGTTACTTCATTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGGATAAAATCGCTTGTGACGGATTTACAACGCAAAGTGCCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTCCCTAAAGGTATTGAGGATCACCTTTTTAGGATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGAACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGATAAATTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACG
TTTCATATCGTCTCATTACCTGATGCAGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2A4GVQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.573	100	0.836