Detailed information NTG0794756

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: PW252_RS10030
• Genome accession: NZ_CP118735
• Coordinates: 2070454..2072904 (-)
• Length: 816 a.a.
• NCBI ID: WP_248049463.1
• Uniprot ID: A0AA96VLY0
• Organism: Streptococcus iners strain 29887
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2065454..2077904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PW252_RS10010 (PW252_10010)	gshAB	2065598..2067838 (+)	2241	WP_248049467.1	bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB	-
PW252_RS10015 (PW252_10015)	hslO	2067908..2068774 (+)	867	WP_248049466.1	Hsp33 family molecular chaperone HslO	-
PW252_RS10020 (PW252_10020)	dusB	2068767..2069771 (+)	1005	WP_248049465.1	tRNA dihydrouridine synthase DusB	-
PW252_RS10025 (PW252_10025)	-	2069867..2070358 (-)	492	WP_248049464.1	adenylyltransferase/cytidyltransferase family protein	-
PW252_RS10030 (PW252_10030)	clpC	2070454..2072904 (-)	2451	WP_248049463.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
PW252_RS10035 (PW252_10035)	-	2072908..2073366 (-)	459	WP_172097756.1	CtsR family transcriptional regulator	-
PW252_RS10040 (PW252_10040)	-	2073642..2073980 (+)	339	WP_248049462.1	thioredoxin domain-containing protein	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90329.14 Da
• Isoelectric Point: 6.8459

>NTDB_id=794756 PW252_RS10030 WP_248049463.1 2070454..2072904(-) (clpC) [Streptococcus iners strain 29887]
MKISTGLQRVFEDAQLVAQRYACEYLETWHILLSFVINHDTVAGAVLAEYPVSISDYEHATFVVTDKVYREDLENFRILP
SSKRLDETASLAKKIAEVVKAKELGTEHLFLAMLLNRRSTASLILDKVGFHLEDSDDKIRFVDLRKSLEKRAGFTKEDMK
AVRGLMKGGKAKPANAGQMMGMPPGPQTGGLEDYTRDLTALAREGKMEPVIGRDAEISRMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVASGDVPVSLSKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQDEYQKHIEKDAALVRRFAKVMIEEPTVEDSIAILSGLKGTFEKYHRVRIGNAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRIKGQVLETGLTSIDKALMAKKYKTVSKLLLEAKEATKASQIYDIEV
TEEDILETLSRLSGIPVTKLSQSDAKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMVKPLLAVTAEKGINLKLQTSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPTGST
LKIGVKGEELKFDVVK

Nucleotide

• Length: 2451 bp

>NTDB_id=794756 PW252_RS10030 WP_248049463.1 2070454..2072904(-) (clpC) [Streptococcus iners strain 29887]
ATGAAGATTTCAACTGGTTTACAAAGGGTATTTGAAGACGCTCAGTTGGTTGCCCAGCGTTATGCCTGTGAGTATTTAGA
AACCTGGCATATTCTCCTGTCCTTTGTCATCAATCATGATACGGTTGCTGGAGCTGTTTTAGCAGAGTATCCAGTTTCTA
TTTCTGATTATGAGCATGCGACCTTTGTTGTGACAGATAAGGTCTATCGTGAAGACTTGGAGAACTTCCGTATCTTGCCG
TCTTCTAAACGTTTGGATGAAACAGCTAGTTTGGCAAAAAAGATTGCGGAAGTGGTCAAGGCCAAGGAGTTGGGAACGGA
ACATCTTTTCCTAGCCATGTTGCTGAACAGACGTTCGACTGCCAGTCTGATTTTGGACAAGGTCGGTTTTCATTTGGAAG
ATTCCGATGACAAGATTCGTTTTGTAGATTTGCGCAAAAGCTTAGAAAAACGTGCAGGATTTACCAAGGAAGATATGAAG
GCTGTTCGTGGCTTGATGAAGGGTGGAAAAGCCAAGCCAGCCAATGCGGGACAGATGATGGGGATGCCTCCTGGTCCCCA
AACGGGTGGACTAGAAGACTATACCCGTGATTTGACTGCACTAGCCCGAGAAGGAAAGATGGAACCTGTTATTGGCCGGG
ATGCTGAAATTTCACGTATGATTCAAATCTTGTCCCGAAAAACAAAAAATAATCCTGTCCTAGTCGGTGATGCGGGTGTC
GGAAAAACGGCTCTTGCTTTGGGCTTGGCTCAACGTGTCGCTTCAGGTGATGTGCCTGTTAGCCTATCTAAGATGCGAGT
ACTAGAACTTGATTTGATGAATGTAATTGCAGGAACTCGTTTCCGTGGTGACTTCGAAGAGCGGATGAACAATATCATCA
ATGACATCGAAGAAGATGGTCAGGTGATACTCTTCATCGATGAGCTGCACACGATTATGGGGTCTGGTTCAGGGATTGAT
TCGACCCTGGATGCGGCCAATATCCTCAAGCCAGCCCTGGCTCGCGGAACTCTTCGGACAGTTGGGGCGACGACCCAAGA
TGAGTACCAAAAGCATATCGAAAAAGATGCGGCCTTGGTACGTCGTTTTGCCAAAGTGATGATTGAAGAGCCGACTGTGG
AAGATAGCATTGCCATTTTGTCTGGTCTAAAAGGGACTTTTGAGAAATACCATAGGGTCCGTATTGGAAATGCAGCTGTT
GAGACTGCCGTAACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCAGCAATCGACTTGCTAGATGAAGC
CAGTGCAACCGTGCAAAATCGTATAAAAGGCCAAGTCTTAGAAACTGGTTTGACAAGTATTGATAAGGCACTGATGGCTA
AAAAATATAAAACCGTGAGTAAGCTATTGCTTGAGGCTAAGGAAGCAACCAAAGCTAGTCAAATCTATGATATAGAAGTA
ACGGAAGAAGATATCTTAGAAACCCTCAGTCGTCTGTCTGGTATTCCAGTGACCAAGCTCAGCCAGTCAGATGCCAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAAGCCATTTCTGCAGTCAGCAGAGCTATTC
GTCGTAATCAGTCAGGTATTCGAACAGGTCGCAGACCGATTGGTTCCTTCATGTTCCTGGGTCCAACTGGTGTCGGTAAA
ACGGAGCTAGCTAAGGCCTTGGCAGAAGTCCTCTTTGATGACGAATCAGCCCTTATCCGTTTTGACATGTCTGAATACAT
GGAGAAATTCGCAGCCAGCCGTCTAAATGGTGCTCCTCCGGGCTATGTGGGCTATGAAGAAGGTGGCGAATTGACGGAGA
AAGTCCGCAACAAACCTTACTCTGTTCTACTCTTTGACGAGGTTGAGAAAGCCCATCCAGATATTTTCAATGTGCTCTTG
CAGGTCTTAGATGATGGTGTTCTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACTATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCACAAGGAAG
TGGAGAAGCGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCTTGACGGAAACTCATATGCAGGATGTTGTCAAGGTTATGGTTAAACCGTTGTTAGCTGTAACAGCTGAGAAAGG
AATTAACCTTAAACTGCAAACGTCCGCCCTTAAGTTACTGGCTAAACAAGGGTATGACCCAGAAATGGGGGCTCGCCCAC
TTCGCAGACTCTTACAAACCAAATTGGAAGATCCTTTGGCAGAGATGTTGCTCCGTGGGGAGTTACCAACTGGTTCAACC
TTGAAGATTGGGGTTAAGGGCGAAGAGCTCAAGTTTGATGTGGTCAAATAG

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (372-451)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-57)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-133)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-366)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	71.534	99.877	0.714
clpC	Streptococcus pneumoniae Rx1	71.534	99.877	0.714
clpC	Streptococcus pneumoniae D39	71.534	99.877	0.714
clpC	Streptococcus mutans UA159	66.585	99.755	0.664
clpC	Streptococcus thermophilus LMD-9	64.277	100	0.659
clpC	Streptococcus thermophilus LMG 18311	64.621	100	0.658
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.461	100	0.506
clpC	Bacillus subtilis subsp. subtilis str. 168	44.35	100	0.447
clpE	Streptococcus mutans UA159	46.299	77.819	0.36