Detailed information NTG0794731

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: PW252_RS02775
• Genome accession: NZ_CP118735
• Coordinates: 532697..534925 (-)
• Length: 742 a.a.
• NCBI ID: WP_248050411.1
• Uniprot ID: A0AA97A5A3
• Organism: Streptococcus iners strain 29887
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 527697..539925

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PW252_RS02755 (PW252_02755)	-	528389..528826 (+)	438	WP_248050417.1	GNAT family N-acetyltransferase	-
PW252_RS02760 (PW252_02760)	ileS	528838..531627 (+)	2790	WP_248050414.1	isoleucine--tRNA ligase	-
PW252_RS02765 (PW252_02765)	-	531712..532020 (-)	309	WP_105113716.1	DUF1827 family protein	-
PW252_RS02770 (PW252_02770)	-	532076..532534 (-)	459	WP_105113717.1	NUDIX hydrolase	-
PW252_RS02775 (PW252_02775)	clpE	532697..534925 (-)	2229	WP_248050411.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
PW252_RS02780 (PW252_02780)	-	535144..535374 (+)	231	WP_024532454.1	DUF1797 family protein	-
PW252_RS02785 (PW252_02785)	-	535499..536179 (+)	681	WP_105109884.1	amino acid ABC transporter permease	-
PW252_RS02790 (PW252_02790)	-	536181..536915 (+)	735	WP_172050118.1	amino acid ABC transporter ATP-binding protein	-
PW252_RS02795 (PW252_02795)	-	537031..537879 (+)	849	WP_248050409.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
PW252_RS02800 (PW252_02800)	-	537957..538865 (-)	909	WP_248050467.1	neutral zinc metallopeptidase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82536.91 Da
• Isoelectric Point: 5.2778

>NTDB_id=794731 PW252_RS02775 WP_248050411.1 532697..534925(-) (clpE) [Streptococcus iners strain 29887]
MLCHNCKINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKKR
DQTPPTQAGGNNGRGGQTPSPQQPQQPNGLLEEFGINMTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETIIILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFSPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSNNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLENPSE
KDLRAVMTSKGNIQIKAHTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=794731 PW252_RS02775 WP_248050411.1 532697..534925(-) (clpE) [Streptococcus iners strain 29887]
ATGCTCTGTCATAACTGTAAAATCAACGATGCAACCATCCATCTCTATACCAATCTAAATGGTAAGCAACAACAGGTAGA
TCTCTGCCATAACTGCTACCAAATTATGAAAACTGACCCTAATAATGCCATCTTGCGTGGTTTAGGGGATTTAACAAACC
CAAATAATATGGACCCTTTCAGCGAGTTCTTCAATCACTTGGGAGGCTATCCAGGAAACACTCCAGCTGGCAAGAAACGT
GACCAAACCCCACCAACACAAGCAGGAGGGAACAACGGGCGTGGTGGGCAAACTCCATCACCTCAGCAACCACAACAACC
AAATGGATTGTTAGAAGAGTTTGGTATCAACATGACGGAAATTGCCCGCCGCGGTGATATTGACCCAGTGATTGGCCGTG
ACCAAGAAATTACACGTGTCATCGAAATCCTCAACCGCCGTACCAAGAACAATCCTGTCCTCATCGGTGAGCCAGGTGTC
GGTAAAACCGCTGTTGTTGAAGGGTTGGCTCAAAAAATTGTCGACGGCGATGTGCCACAAAAATTGCAAGGTAAGGAAGT
CATCCGATTAGATGTTGTCAGCCTGGTACAAGGAACTGGTATCCGTGGTCAATTTGAAGAACGTATGCAAAAACTAATGG
AAGAAATCCGTAATCGTCGTGAGATTATCCTCTTTATCGACGAAATCCACGAGATTGTCGGTGCTGGCTCTGCTGGTGAT
GGCAATATGGATGCTGGAAATATCCTCAAACCTGCCCTTGCCCGTGGCGAAATGCAGCTAGTCGGTGCAACAACCCTCAA
CGAATACCGTATTATCGAGAAGGATGCAGCCTTAGAACGCCGTATGCAACCTGTAAAGGTCGAAGAACCAAGCGTTGAAG
AAACCATTATCATTCTCAAGGGTATCCAGAATAAGTATCAGGACTACCACCATGTCAAATACTCTGACGCCGCTATTGAA
GCTGCTGCGGTCCTTTCAAATCGCTATATCCAAGACCGTTTCTTGCCAGACAAGGCCATTGACCTACTGGACGAAGCTGG
TTCTAAAATGAACCTGACCCTCAATTTTGTTGATCCAAAAGAAATCGACCAACGTTTGATTGATGCCGAAAATCGTAAGG
CCCAAGCAACTCGTGACGAGGACTATGAAAAGGCTGCCTATTTCCGTGACCAGATTGCCAAGTATAAGGAAATGCAAAAG
GCAACCATCAGCGAGGAAGACATTCCCCTCATTACTGAAAAGGAAATTGAAGCCATCGTAGAACAAAAAACCAACATACC
TGTTGGCGATTTGAAAGAAAAAGAACAATCTCAATTAATCAACCTGGCTAGCGATCTCAAGGCACATGTTATCGGTCAAG
ATGAAGCTGTTGATAAGATTGCCAAGGCCATTCGCCGCAACCGTGTTGGTCTTGGTGCCCCAAACCGCCCAATTGGCTCC
TTCCTCTTTGTTGGACCTACCGGTGTCGGTAAAACAGAGCTGTCCAAGCAACTAGCGATTGAACTCTTCGGTTCAGCCGA
TAGTATGATTCGCTTCGATATGTCTGAGTACATGGAGAAACATGCCGTTGCCAAGCTAGTCGGTGCCCCTCCAGGTTATG
TAGGCTATGAAGAAGCCGGTCAGCTAACGGAAAAAGTCCGCCGCAATCCTTACTCTCTCATCCTCTTGGATGAGGTAGAA
AAAGCTCACCCTGATGTCATGCACATGTTCCTCCAAGTCCTAGACGACGGCCGTCTGACAGATGGACAGGGACGCACAGT
CAGCTTCAAGGACACCATTATCATCATGACTTCAAATGCTGGAACTGGTAAGGTTGAAGCAAGTGTAGGCTTTGGAGCAG
CCATGGAAGGTCGCACCCAGTCGGTTCTTGGCCAACTCAGCAATTTCTTCAGTCCAGAATTCATGAACCGCTTTGACGGA
ATCATCGAGTTCCAACCACTCAGCAAGGAAAACCTTCTCGAAATTGTCAGCCTCATGCTTGATGATGTCAACAAACGCTT
GTCTAACAACGGTATTAGCTTACATGTGACAGATAAGGTCAAAGAAAAGCTAGTTGATCTAGGTTACGATCCCAAAATGG
GGGCTCGGCCACTACGCAGAACCATCCAAGATCAAATCGAAGATGCCATTACAGACTTTTACTTGGAAAACCCAAGCGAA
AAAGACCTTCGCGCTGTTATGACCAGCAAGGGGAACATTCAAATCAAGGCACATACAAAAACAAAATAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (153-273)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• AAA lid domain (AAA_lid_9) (291-389)

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	83.289	100	0.846
clpE	Streptococcus pneumoniae D39	83.289	100	0.846
clpE	Streptococcus pneumoniae R6	83.289	100	0.846
clpE	Streptococcus pneumoniae TIGR4	83.289	100	0.846
clpE	Streptococcus mutans UA159	82.777	100	0.836
clpC	Lactococcus lactis subsp. cremoris KW2	77.793	97.709	0.76
clpC	Bacillus subtilis subsp. subtilis str. 168	50.735	91.644	0.465
clpC	Streptococcus thermophilus LMD-9	48.089	84.636	0.407
clpC	Streptococcus mutans UA159	48.397	84.097	0.407
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.455	88.949	0.404
clpC	Streptococcus thermophilus LMG 18311	47.771	84.636	0.404
clpC	Streptococcus pneumoniae D39	47.84	84.232	0.403
clpC	Streptococcus pneumoniae TIGR4	47.84	84.232	0.403
clpC	Streptococcus pneumoniae Rx1	47.84	84.232	0.403