Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   PW220_RS07705 Genome accession   NZ_CP118734
Coordinates   1538429..1540657 (+) Length   742 a.a.
NCBI ID   WP_248054050.1    Uniprot ID   A0AA96VF25
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1533429..1545657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS07680 (PW220_07685) - 1534487..1535395 (+) 909 WP_248032653.1 neutral zinc metallopeptidase -
  PW220_RS07685 (PW220_07690) - 1535474..1536322 (-) 849 WP_105117507.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  PW220_RS07690 (PW220_07695) - 1536439..1537173 (-) 735 WP_105113720.1 amino acid ABC transporter ATP-binding protein -
  PW220_RS07695 (PW220_07700) - 1537175..1537855 (-) 681 WP_105109884.1 amino acid ABC transporter permease -
  PW220_RS07700 (PW220_07705) - 1537980..1538210 (-) 231 WP_024532454.1 DUF1797 family protein -
  PW220_RS07705 (PW220_07710) clpE 1538429..1540657 (+) 2229 WP_248054050.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  PW220_RS07710 (PW220_07715) - 1540968..1541426 (+) 459 WP_105113717.1 NUDIX hydrolase -
  PW220_RS07715 (PW220_07720) - 1541482..1541790 (+) 309 WP_105113716.1 DUF1827 family protein -
  PW220_RS07720 (PW220_07725) ileS 1541875..1544664 (-) 2790 WP_248054049.1 isoleucine--tRNA ligase -
  PW220_RS07725 (PW220_07730) - 1544677..1545114 (-) 438 WP_044692224.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 82496.86 Da        Isoelectric Point: 5.2778

>NTDB_id=794700 PW220_RS07705 WP_248054050.1 1538429..1540657(+) (clpE) [Streptococcus iners subsp. hyiners strain 29892]
MLCHNCKINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKKR
DQTPPTQAGGNNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETIIILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFSPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSNNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLENPSE
KDLRAVMTSKGNIQIKAHTKTK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=794700 PW220_RS07705 WP_248054050.1 1538429..1540657(+) (clpE) [Streptococcus iners subsp. hyiners strain 29892]
ATGCTCTGTCATAACTGTAAAATCAACGATGCAACCATCCATCTCTATACCAATCTGAATGGTAAGCAACAACAGGTAGA
TCTCTGCCACAACTGCTACCAAATTATGAAAACTGATCCTAATAATGCCATCTTGCGTGGTTTAGGGGATTTAACAAACC
CAAATAATATGGACCCTTTCAGCGAGTTCTTCAATCACTTGGGAGGCTATCCAGGAAACACTCCAGCTGGCAAGAAACGT
GACCAAACCCCACCAACACAAGCAGGAGGGAACAACGGGCGTGGTGGGCAAACTCCACCACCTCAGCAACCCCAACAACC
AAATGGACTTTTAGAAGAGTTTGGTATCAACGTGACGGAAATTGCCCGTCGCGGAGATATTGACCCAGTGATTGGCCGTG
ACCAAGAAATTACGCGTGTCATCGAAATCCTCAACCGCCGTACCAAGAACAACCCTGTCCTCATCGGTGAGCCAGGTGTC
GGTAAAACCGCTGTTGTTGAAGGGTTGGCTCAAAAAATTGTCGACGGCGACGTGCCACAAAAATTGCAAGGTAAGGAAGT
CATCCGATTAGATGTTGTCAGCCTGGTACAAGGGACTGGTATCCGTGGTCAATTTGAAGAACGCATGCAAAAACTCATAG
AGGAAATCCGTAATCGTCGTGAGATTATCCTCTTTATCGACGAAATCCACGAGATTGTCGGTGCTGGATCTGCTGGTGAT
GGCAATATGGATGCTGGAAATATCCTCAAACCTGCCCTTGCCCGTGGTGAAATGCAGCTAGTCGGTGCAACAACCCTCAA
CGAATACCGTATTATCGAGAAGGATGCAGCCTTAGAACGCCGTATGCAACCTGTAAAGGTCGAAGAACCAAGCGTTGAAG
AAACCATTATCATTCTCAAGGGTATCCAGAATAAGTATCAGGACTATCACCATGTCAAATACTCTGACGCAGCTATTGAA
GCTGCTGCTGTCCTTTCAAATCGCTATATTCAAGACCGTTTCTTGCCAGACAAGGCCATTGACCTACTGGACGAAGCTGG
TTCTAAGATGAACCTGACCCTCAATTTTGTTGATCCAAAAGAAATCGACCAACGCTTGATTGATGCCGAAAATCGTAAGG
CCCAAGCAACTCGTGATGAGGACTACGAGAAGGCTGCCTATTTCCGCGACCAGATTGCCAAGTATAAGGAAATGCAAAAG
GCAACCATCAGCGAGGAAGATATTCCCCTCATTACTGAAAAGGAAATTGAAGCCATCGTAGAACAAAAAACCAACATCCC
TGTTGGTGATTTGAAAGAAAAAGAACAATCTCAACTCATCAACCTGGCTAGCGACCTCAAGGCCCATGTTATTGGTCAAG
ATGAAGCTGTAGACAAAATCGCCAAGGCCATTCGCCGCAACCGTGTTGGTCTTGGAGCGCCAAACCGCCCAATCGGCTCC
TTCCTATTTGTCGGACCAACCGGTGTCGGTAAAACAGAACTATCCAAACAATTAGCCATCGAACTCTTCGGTTCTGCCGA
TAGTATGATTCGCTTCGATATGTCTGAGTACATGGAGAAACATGCCGTTGCCAAGCTAGTCGGTGCCCCTCCAGGCTATG
TAGGCTATGAAGAAGCCGGTCAGCTAACTGAAAAAGTCCGCCGCAATCCTTACTCTCTCATCCTCTTGGATGAAGTAGAA
AAAGCCCACCCTGATGTCATGCACATGTTCCTCCAAGTTCTCGATGACGGCCGTCTGACAGATGGTCAGGGACGCACAGT
CAGCTTCAAGGACACCATTATCATCATGACTTCAAATGCTGGAACTGGTAAGGTTGAAGCAAGTGTAGGCTTTGGAGCAG
CCATGGAAGGTCGCACCCAGTCGGTTCTTGGCCAACTCAGCAATTTCTTCAGTCCAGAATTCATGAACCGCTTTGACGGA
ATCATCGAGTTCCAACCACTCAGCAAGGAAAACCTCCTCGAAATTGTCAGCCTCATGCTGGATGATGTCAACAAACGCTT
GTCTAACAACGGTATTAGCTTACATGTGACAGATAAGGTCAAAGAAAAGCTAGTTGATCTAGGTTACGATCCCAAAATGG
GGGCTCGGCCACTACGCAGAACTATCCAAGACCAAATTGAAGATGCCATTACAGACTTTTACTTGGAAAACCCAAGCGAA
AAAGACCTTCGCGCTGTTATGACCAGCAAGGGGAACATTCAAATCAAGGCACATACAAAAACAAAATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(153-273)

AAA lid domain (AAA_lid_9)

(291-389)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(647-721)

AAA domain (Cdc48 subfamily) (AAA_2)

(476-639)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

83.422

100

0.848
  clpE Streptococcus pneumoniae D39

83.422

100

0.848
  clpE Streptococcus pneumoniae R6

83.422

100

0.848
  clpE Streptococcus pneumoniae TIGR4

83.422

100

0.848
  clpE Streptococcus mutans UA159

82.777

100

0.836
  clpC Lactococcus lactis subsp. cremoris KW2

77.655

97.709

0.759
  clpC Bacillus subtilis subsp. subtilis str. 168

52

87.601

0.456
  clpC Streptococcus mutans UA159

48.558

84.097

0.408
  clpC Streptococcus thermophilus LMD-9

48.248

84.636

0.408
  clpC Streptococcus thermophilus LMG 18311

47.93

84.636

0.406
  clpC Streptococcus pneumoniae TIGR4

48

84.232

0.404
  clpC Streptococcus pneumoniae Rx1

48

84.232

0.404
  clpC Streptococcus pneumoniae D39

48

84.232

0.404
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.975

84.636

0.398