Detailed information NTG0794623

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: PXH68_RS02375
• Genome accession: NZ_CP118733
• Coordinates: 498966..501203 (-)
• Length: 745 a.a.
• NCBI ID: WP_248028267.1
• Uniprot ID: A0AA96VG55
• Organism: Streptococcus suivaginalis strain 29896
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 493966..506203

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PXH68_RS02360 (PXH68_02360)	-	496934..497239 (-)	306	WP_158455495.1	DUF1827 family protein	-
PXH68_RS02365 (PXH68_02365)	-	497291..497749 (-)	459	WP_248028269.1	NUDIX hydrolase	-
PXH68_RS02370 (PXH68_02370)	-	497921..498916 (+)	996	WP_248028268.1	MBL fold metallo-hydrolase	-
PXH68_RS02375 (PXH68_02375)	clpE	498966..501203 (-)	2238	WP_248028267.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
PXH68_RS02380 (PXH68_02380)	-	501548..501778 (+)	231	WP_158455487.1	DUF1797 family protein	-
PXH68_RS02385 (PXH68_02385)	-	501895..502584 (+)	690	WP_172043662.1	amino acid ABC transporter permease	-
PXH68_RS02390 (PXH68_02390)	-	502577..503311 (+)	735	WP_158455483.1	amino acid ABC transporter ATP-binding protein	-
PXH68_RS02395 (PXH68_02395)	-	503429..504277 (+)	849	WP_248028271.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
PXH68_RS02400 (PXH68_02400)	-	504399..505750 (+)	1352	WP_316715801.1	IS3 family transposase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 82890.29 Da
• Isoelectric Point: 5.5910

>NTDB_id=794623 PXH68_RS02375 WP_248028267.1 498966..501203(-) (clpE) [Streptococcus suivaginalis strain 29896]
MLCHNCKINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILKGLGDLANPNNMDPFSEFFNHLGSYPGHTPAGKAR
NQTPPTQSGGGSNGNGGHQQPPQKPNGLLEEFGINVTEIARRGDIDPVIGRDQEIRRVIEILNRRTKNNPVLIGEPGVGK
TAVVEGLAQKIVDGDVPQKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGDGN
MDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQSKYQDYHHVKYTDAAIAAA
AVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIEAENRKAQATRDEDYEKAAYYRDQIAKYKEMQKAT
LSEEDTPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFL
FVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVEKA
HPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTHSVLNQLGNFFSPEFMNRFDGII
EFQPLSKENLLEIVSLMLEDVNKRLSNNGINLHVTEKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPQEKD
LRAIMNPKGDIIIKANQKKVNHPTE

Nucleotide

• Length: 2238 bp

>NTDB_id=794623 PXH68_RS02375 WP_248028267.1 498966..501203(-) (clpE) [Streptococcus suivaginalis strain 29896]
ATGCTTTGCCATAACTGTAAAATCAATGACGCAACCATCCATCTCTATACCAACCTAAACGGAAAACAACAACAGGTTGA
CCTCTGCCACAACTGCTATCAAATCATGAAAACTGATCCTAATAATGCCATTTTGAAAGGGCTCGGTGATTTAGCCAATC
CCAACAATATGGATCCCTTCAGCGAATTTTTCAATCATCTAGGTAGCTATCCAGGTCATACACCAGCAGGAAAGGCACGA
AACCAAACACCACCTACACAGTCAGGTGGAGGCAGCAATGGCAATGGTGGTCATCAGCAGCCACCACAAAAGCCAAACGG
TTTATTAGAAGAGTTTGGTATCAATGTCACAGAAATTGCCCGTCGTGGCGATATTGATCCTGTCATTGGTCGCGATCAAG
AAATCCGACGAGTGATTGAAATTCTCAACCGCCGTACTAAGAACAACCCAGTTCTCATTGGCGAGCCAGGTGTTGGTAAA
ACCGCTGTCGTTGAAGGCCTGGCCCAAAAAATTGTGGATGGCGATGTACCACAAAAATTGCAAGGTAAGGAAGTCATCCG
CCTTGATGTTGTTAGCCTTGTTCAAGGAACTGGTATCCGAGGTCAGTTTGAAGAACGCATGCAAAAACTCATGGAAGAAA
TCCGGAACCGTCGCGAGATTATCCTCTTTATTGACGAAATCCATGAGATAGTTGGTGCAGGTTCAGCAGGCGATGGCAAT
ATGGATGCAGGCAATATCCTCAAACCGGCCCTAGCACGTGGAGAAATGCAACTGGTTGGAGCAACTACGCTAAATGAGTA
CCGTATTATCGAAAAAGATGCAGCCTTAGAACGCCGGATGCAGCCTGTAAAGGTTGATGAGCCGAGTGTGGAGGAAACTA
TTACCATTCTCAAGGGTATTCAGAGCAAGTACCAGGACTACCATCATGTCAAATATACGGATGCAGCAATCGCGGCCGCT
GCAGTTCTCTCTAACCGTTACATTCAGGATCGCTTCTTACCAGATAAAGCCATTGACCTTTTGGATGAGGCAGGCTCTAA
GATGAACTTGACCCTCAACTTTGTAGATCCCAAAGAAATTGATCAACGCTTGATCGAAGCTGAAAATCGTAAAGCACAAG
CTACCCGCGACGAAGATTACGAAAAAGCAGCCTACTACCGTGACCAAATCGCCAAATACAAGGAAATGCAAAAGGCAACC
TTGAGCGAAGAAGACACACCACTCATTACTGAAAAAGAAATCGAAGCCATTGTCGAACAAAAAACCAATATCCCCGTTGG
TGACCTCAAAGAAAAAGAGCAATCTCAACTCATCAACCTAGCCAGCGACCTCAAAGCCCACGTCATTGGACAAGATGACG
CAGTGGATAAGATTGCCAAGGCCATTCGCCGCAACCGTGTTGGCCTAGGAGCGCCGAATCGTCCAATCGGCTCCTTCCTC
TTTGTCGGACCAACAGGTGTCGGAAAAACCGAACTGTCCAAACAATTAGCCATTGAACTCTTTGGTTCAGCAGACAGTAT
GATCCGCTTCGATATGTCTGAATATATGGAGAAACATGCTGTAGCCAAGCTAGTTGGTGCTCCTCCAGGATATGTGGGCT
ATGAAGAAGCCGGTCAACTAACTGAAAAAGTACGCCGTAATCCTTACTCCCTCATCTTGCTCGATGAGGTTGAAAAAGCC
CACCCTGATGTTATGCATATGTTCCTTCAGGTTCTAGACGATGGGCGCTTGACAGATGGACAAGGTCGAACTGTCAGCTT
TAAGGATACTATCATTATCATGACATCAAATGCTGGTACTGGGAAAGTGGAAGCCAGCGTCGGATTCGGTGCAGCAATGG
AAGGCAGAACCCACTCTGTTCTGAACCAACTCGGTAACTTCTTTAGTCCAGAATTTATGAACCGCTTTGACGGTATCATC
GAATTTCAGCCACTCAGCAAGGAAAACCTTCTCGAAATTGTCAGCCTCATGTTAGAAGATGTTAACAAGCGCCTTTCTAA
CAATGGTATCAATCTCCATGTTACTGAAAAGGTCAAGGAAAAACTGGTTGACTTGGGTTACGATCCAAAAATGGGAGCTC
GTCCACTCCGCAGAACCATTCAGGATCAGATTGAGGATGCCATTACGGATTTCTATCTGGAGCATCCGCAAGAAAAAGAC
TTGCGTGCCATCATGAATCCTAAGGGCGACATCATCATCAAAGCCAATCAGAAAAAAGTAAATCACCCCACTGAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (645-716)

• AAA lid domain (AAA_lid_9) (289-387)

• ATPase family associated with various cellular activities (AAA) (AAA) (151-270)

• AAA domain (Cdc48 subfamily) (AAA_2) (474-637)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.911	100	0.834
clpE	Streptococcus pneumoniae D39	82.911	100	0.834
clpE	Streptococcus pneumoniae R6	82.911	100	0.834
clpE	Streptococcus pneumoniae TIGR4	82.911	100	0.834
clpE	Streptococcus mutans UA159	82.842	100	0.83
clpC	Lactococcus lactis subsp. cremoris KW2	76.892	99.329	0.764
clpC	Bacillus subtilis subsp. subtilis str. 168	50.665	90.872	0.46
clpC	Streptococcus thermophilus LMD-9	47.278	86.309	0.408
clpC	Streptococcus thermophilus LMG 18311	46.967	86.309	0.405
clpC	Streptococcus pneumoniae Rx1	48.16	83.893	0.404
clpC	Streptococcus pneumoniae TIGR4	48.16	83.893	0.404
clpC	Streptococcus pneumoniae D39	48.16	83.893	0.404
clpC	Streptococcus mutans UA159	47.923	84.027	0.403
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.293	84.295	0.399