Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EPR_RS02120 Genome accession   NZ_AP022847
Coordinates   385872..387692 (-) Length   606 a.a.
NCBI ID   WP_200763604.1    Uniprot ID   -
Organism   Nitrosophilus alvini strain EPR55-1     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 380872..392692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EPR_RS02105 - 383466..383864 (-) 399 WP_200763599.1 tetratricopeptide repeat protein -
  EPR_RS02110 - 383886..385328 (-) 1443 WP_200763601.1 Hpt domain-containing protein -
  EPR_RS02115 - 385344..385760 (-) 417 WP_200763602.1 PAS domain-containing protein -
  EPR_RS02120 uvrC 385872..387692 (-) 1821 WP_200763604.1 excinuclease ABC subunit UvrC Machinery gene
  EPR_RS02125 - 387676..388104 (-) 429 WP_200763606.1 hypothetical protein -
  EPR_RS02130 nadB 388227..389663 (+) 1437 WP_200763608.1 L-aspartate oxidase -
  EPR_RS02135 nhaD 389728..391029 (+) 1302 WP_200763609.1 sodium:proton antiporter NhaD -
  EPR_RS02140 guaA 391066..392616 (+) 1551 WP_200763610.1 glutamine-hydrolyzing GMP synthase -

Sequence

Protein


Download         Length: 606 a.a.        Molecular weight: 70022.50 Da        Isoelectric Point: 10.1616

>NTDB_id=79429 EPR_RS02120 WP_200763604.1 385872..387692(-) (uvrC) [Nitrosophilus alvini strain EPR55-1]
MSKANEKLKNDIKNLPDKPGVYQYFNKEGRLLYIGKAKSLKKRVKSYFRFSPHFCPAPNLSPRIFKMASEVDALEYIIVE
NENDALILENSLIKQLKPKYNILLRDDKTYPYIYINMSEEFPRFEITRKVIKGKNIKYFGPLSTAAKDILDSIYELFPLV
QKKGCLNQKKACLFYQIKRCSAPCEGKISTKEYKNIVDEAKKYILDKKTLIKKLEAKMSRLSAELRFEEAAEIRDRIERI
SKSEIQSNIDLARVEDIDIFAVYSEKGKASIVRMFMREGRVISSSSNIIRYDDTKGFDVDEAYKRAILDFYSVDSPITSK
KIITAHDFSDRKTVESFLSQKLGKKITISTPKKGNKLNLAKLAILNAKELLKKQSKEKDDILLQVMKLLKLENYPFRIEI
FDNSHIKGSIPVGAMAVYENGKFKKNDYRHYNLSSKDEYSQMREILTKRCNSFSKNPPPDLWVIDGGETLRRLAQDILQS
FGVDIDVVAISKEKIDAKAYRAKGKAKDLIYTKNELFRLQPTDKRLLFLQKLRDEAHRFAIKFHREQKLKADRRISILKA
KGIGEAKLKKLLDYFGSFENIKSASFSDLCSIIDEKSAKNIKNADF

Nucleotide


Download         Length: 1821 bp        

>NTDB_id=79429 EPR_RS02120 WP_200763604.1 385872..387692(-) (uvrC) [Nitrosophilus alvini strain EPR55-1]
ATGTCGAAAGCAAATGAGAAATTGAAAAACGATATCAAAAACCTTCCTGACAAACCGGGAGTCTATCAGTACTTCAATAA
AGAGGGCAGACTTCTTTATATCGGCAAAGCAAAAAGTCTCAAAAAAAGAGTCAAAAGCTATTTCAGATTTTCACCGCACT
TCTGCCCCGCACCAAATCTAAGCCCAAGAATTTTCAAAATGGCAAGTGAAGTGGATGCTCTAGAATATATAATCGTTGAA
AATGAAAACGATGCACTTATTCTTGAAAACTCCCTCATAAAACAACTTAAACCCAAATACAATATTCTTTTAAGAGACGA
TAAAACATATCCCTACATCTACATAAATATGAGCGAAGAGTTTCCCAGATTTGAGATAACCAGAAAAGTTATAAAAGGGA
AAAATATCAAATACTTCGGGCCTCTTTCCACCGCAGCAAAAGATATACTCGACTCCATATACGAGCTTTTTCCGCTCGTT
CAGAAAAAAGGATGCCTCAATCAAAAAAAAGCGTGCCTTTTCTATCAGATAAAAAGATGTTCTGCTCCGTGCGAAGGAAA
AATTTCCACAAAAGAGTATAAAAATATAGTAGATGAGGCAAAAAAGTATATTCTGGACAAAAAAACACTCATAAAAAAAC
TTGAAGCTAAAATGTCCCGGTTATCGGCAGAGTTGAGATTTGAAGAGGCTGCCGAAATCAGGGACAGAATCGAACGGATC
TCAAAAAGCGAAATACAGAGCAATATCGATCTTGCACGAGTAGAAGACATCGATATTTTTGCTGTATACAGCGAAAAAGG
CAAAGCTTCTATTGTCAGAATGTTTATGCGGGAAGGAAGAGTGATTTCAAGCTCTTCAAATATAATCAGGTACGATGATA
CAAAAGGATTCGATGTTGATGAGGCCTACAAAAGAGCTATTCTTGATTTCTATTCTGTCGATTCACCTATAACTTCCAAA
AAAATCATCACTGCACACGATTTTTCGGATAGAAAAACTGTAGAGTCTTTTCTTTCGCAAAAACTGGGGAAAAAAATAAC
AATTTCCACCCCAAAAAAAGGCAATAAGTTAAATCTTGCAAAGCTTGCAATACTTAACGCAAAAGAGCTTTTGAAAAAGC
AATCCAAAGAAAAAGATGATATCCTGTTGCAGGTTATGAAACTTTTGAAGCTGGAAAATTATCCGTTTAGAATAGAAATT
TTCGACAACTCCCATATTAAAGGGTCAATTCCGGTAGGCGCAATGGCTGTATACGAAAACGGAAAGTTCAAAAAAAATGA
TTACAGACATTACAATCTCTCTTCAAAAGATGAATATTCCCAGATGAGAGAGATACTTACAAAAAGATGCAACAGTTTTT
CGAAAAATCCACCTCCCGATCTTTGGGTTATAGACGGCGGAGAGACACTAAGACGTCTGGCACAGGATATTTTACAAAGT
TTCGGCGTAGATATTGATGTAGTTGCAATATCTAAAGAGAAAATAGATGCAAAAGCATACAGAGCAAAAGGAAAAGCCAA
AGATTTGATATATACTAAAAATGAGCTCTTTAGATTACAACCGACAGACAAAAGACTTCTCTTTTTACAAAAATTGCGGG
ATGAAGCCCACAGATTCGCCATAAAGTTTCACAGAGAACAGAAACTAAAAGCCGATCGTCGCATTTCTATTCTAAAAGCA
AAAGGTATTGGGGAAGCCAAGCTTAAAAAGCTTTTGGACTATTTCGGATCATTTGAAAATATAAAATCGGCCTCCTTTTC
TGATCTTTGCAGTATCATCGATGAAAAAAGCGCAAAAAACATAAAAAACGCAGATTTTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(208-242)

GIY-YIG catalytic domain (GIY-YIG)

(19-101)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(387-541)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

54.561

95.875

0.523

Multiple sequence alignment