Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   PWF74_RS08960 Genome accession   NZ_CP118627
Coordinates   1795598..1796641 (-) Length   347 a.a.
NCBI ID   WP_074751408.1    Uniprot ID   A0A1I4HNE3
Organism   Lactococcus garvieae strain Pa-2     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1790598..1801641
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWF74_RS08945 (PWF74_08945) rpsB 1790635..1791408 (-) 774 WP_003133158.1 30S ribosomal protein S2 -
  PWF74_RS08950 (PWF74_08950) - 1791681..1792721 (+) 1041 WP_074751412.1 lactonase family protein -
  PWF74_RS08955 (PWF74_08955) adhE 1792875..1795568 (+) 2694 WP_165706176.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase -
  PWF74_RS08960 (PWF74_08960) sepM 1795598..1796641 (-) 1044 WP_074751408.1 SepM family pheromone-processing serine protease Regulator
  PWF74_RS08965 (PWF74_08965) coaD 1796631..1797128 (-) 498 WP_003133151.1 pantetheine-phosphate adenylyltransferase -
  PWF74_RS08970 (PWF74_08970) rsmD 1797118..1797657 (-) 540 WP_165706175.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  PWF74_RS08975 (PWF74_08975) - 1797751..1799097 (-) 1347 WP_003133148.1 glucose-6-phosphate isomerase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 37830.13 Da        Isoelectric Point: 6.9825

>NTDB_id=794064 PWF74_RS08960 WP_074751408.1 1795598..1796641(-) (sepM) [Lactococcus garvieae strain Pa-2]
MKNEKIKKHKKLKLFFAIALPLLIVVGLFFPLPYYIEQPGGTIPVNQMVDVAGKKDEHKGNFYLTTVEMVRANAASMLYS
KSNSFATILSSEEMTGGMTNQQFDLVNQFYMQTAQNTAVYQAFKLAGKPYEMKYQGVYVLSITEDSTFKNDLQLSDTITA
VNGHTFKSSTEMIDYVSQQKVGDEVTIKYTRVDGSNHEATGKYIKLSNGKTGIGIGLVDHTQVVTDPKVKIDAGSIGGPS
AGMMFTLEIYSQITGKDLRQGREIAGTGTINEDGSIGQIGGVDKKVATASNSGAKIFLCPDETEEQAKASGTTNNYTDAL
AAAKKLNTDMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=794064 PWF74_RS08960 WP_074751408.1 1795598..1796641(-) (sepM) [Lactococcus garvieae strain Pa-2]
ATGAAAAATGAAAAAATAAAAAAGCATAAAAAACTAAAGCTATTCTTTGCCATTGCGTTACCGCTTCTTATTGTAGTGGG
TTTGTTCTTCCCCTTACCTTACTATATCGAGCAGCCAGGAGGAACCATTCCAGTTAATCAGATGGTCGATGTTGCGGGAA
AGAAAGATGAACATAAAGGCAATTTTTATTTAACGACTGTTGAAATGGTACGGGCCAATGCTGCAAGTATGCTTTATTCC
AAGTCGAACTCTTTTGCCACTATTTTGAGTAGTGAAGAGATGACGGGTGGGATGACCAATCAGCAATTTGATTTGGTCAA
CCAGTTCTATATGCAGACCGCGCAGAATACAGCTGTTTATCAGGCCTTTAAGTTGGCAGGGAAACCTTATGAGATGAAGT
ATCAAGGGGTCTACGTTTTGAGTATCACTGAGGATTCGACATTTAAAAATGACTTGCAACTTTCGGATACGATAACGGCA
GTTAATGGCCACACTTTCAAATCTTCAACTGAGATGATTGACTATGTGTCTCAACAAAAAGTTGGAGATGAGGTGACTAT
CAAGTACACACGGGTGGATGGCAGCAACCATGAAGCCACAGGCAAGTACATTAAGTTGAGTAATGGTAAAACAGGGATTG
GCATTGGTTTAGTAGATCATACACAGGTTGTGACAGACCCTAAAGTTAAAATCGATGCCGGAAGTATTGGCGGGCCAAGT
GCTGGGATGATGTTTACCTTGGAAATATATAGCCAAATCACAGGCAAAGATTTACGTCAAGGACGCGAAATTGCAGGTAC
TGGAACGATCAATGAAGATGGCAGCATCGGGCAAATAGGCGGCGTTGATAAAAAAGTTGCTACAGCAAGCAATTCGGGCG
CTAAAATTTTCCTTTGCCCGGATGAAACGGAAGAACAGGCAAAGGCTTCTGGTACAACAAATAACTATACAGATGCACTT
GCGGCAGCTAAAAAGTTGAATACAGATATGAAAATCGTACCTGTAAAGACGATCCAAGATGCACTAGACTATCTCGAAAA
ATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(229-308)

PDZ domain (PDZ_2)

(134-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4HNE3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

49.28

100

0.493