Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   PWA59_RS16535 Genome accession   NZ_CP118541
Coordinates   3270065..3270709 (-) Length   214 a.a.
NCBI ID   WP_014418762.1    Uniprot ID   A0A2Z4EIP2
Organism   Bacillus velezensis strain HC-5     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3265065..3275709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWA59_RS16500 (PWA59_16500) - 3266250..3266681 (+) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -
  PWA59_RS16505 (PWA59_16505) - 3266681..3267022 (+) 342 WP_014418758.1 Na(+)/H(+) antiporter subunit C -
  PWA59_RS16510 (PWA59_16510) - 3267015..3268496 (+) 1482 WP_014418759.1 Na+/H+ antiporter subunit D -
  PWA59_RS16515 (PWA59_16515) - 3268502..3268978 (+) 477 WP_014418760.1 Na+/H+ antiporter subunit E -
  PWA59_RS16520 (PWA59_16520) - 3268978..3269262 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  PWA59_RS16525 (PWA59_16525) mnhG 3269246..3269620 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  PWA59_RS16530 (PWA59_16530) - 3269660..3270043 (-) 384 WP_014418761.1 hotdog fold thioesterase -
  PWA59_RS16535 (PWA59_16535) comA 3270065..3270709 (-) 645 WP_014418762.1 response regulator transcription factor Regulator
  PWA59_RS16540 (PWA59_16540) comP 3270790..3273141 (-) 2352 WP_269800792.1 histidine kinase Regulator
  PWA59_RS16545 (PWA59_16545) comX 3273119..3273289 (-) 171 WP_032863917.1 competence pheromone ComX -
  PWA59_RS16550 (PWA59_16550) - 3273289..3274215 (-) 927 WP_014721741.1 polyprenyl synthetase family protein -
  PWA59_RS16555 (PWA59_16555) degQ 3274346..3274486 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  PWA59_RS16560 (PWA59_16560) - 3274952..3275293 (+) 342 WP_014418765.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24302.70 Da        Isoelectric Point: 4.9953

>NTDB_id=793127 PWA59_RS16535 WP_014418762.1 3270065..3270709(-) (comA) [Bacillus velezensis strain HC-5]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTQRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=793127 PWA59_RS16535 WP_014418762.1 3270065..3270709(-) (comA) [Bacillus velezensis strain HC-5]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTTCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACACAGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGTTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z4EIP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

85.981

100

0.86