Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   PWK66_RS08745 Genome accession   NZ_CP118482
Coordinates   1748999..1749712 (+) Length   237 a.a.
NCBI ID   WP_002991336.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 20160179     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1743999..1754712
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWK66_RS08735 (PWK66_08685) treC 1745069..1746697 (-) 1629 WP_002991331.1 alpha,alpha-phosphotrehalase -
  PWK66_RS08740 (PWK66_08690) treP 1746764..1748788 (-) 2025 WP_002991333.1 PTS system trehalose-specific EIIBC component -
  PWK66_RS08745 (PWK66_08695) treR 1748999..1749712 (+) 714 WP_002991336.1 trehalose operon repressor Regulator
  PWK66_RS08750 (PWK66_08700) - 1749991..1750329 (-) 339 WP_002991339.1 helix-turn-helix domain-containing protein -
  PWK66_RS08755 (PWK66_08705) - 1750515..1751363 (+) 849 Protein_1664 VOC family protein -
  PWK66_RS08760 (PWK66_08710) yaaA 1751405..1752136 (+) 732 WP_002991342.1 peroxide stress protein YaaA -
  PWK66_RS08765 (PWK66_08715) nrdG 1752310..1752924 (-) 615 WP_002991344.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  PWK66_RS08770 (PWK66_08720) - 1752924..1753433 (-) 510 WP_002991345.1 GNAT family N-acetyltransferase -
  PWK66_RS08775 (PWK66_08725) - 1753442..1754377 (-) 936 WP_002991347.1 Gfo/Idh/MocA family protein -
  PWK66_RS08780 (PWK66_08730) - 1754406..1754552 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27608.78 Da        Isoelectric Point: 9.6226

>NTDB_id=792741 PWK66_RS08745 WP_002991336.1 1748999..1749712(+) (treR) [Streptococcus pyogenes strain 20160179]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFSRRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=792741 PWK66_RS08745 WP_002991336.1 1748999..1749712(+) (treR) [Streptococcus pyogenes strain 20160179]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTTTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTTCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675