Detailed information    

insolico Bioinformatically predicted

Overview

Name   recA   Type   Machinery gene
Locus tag   PWK66_RS08815 Genome accession   NZ_CP118482
Coordinates   1760805..1761941 (-) Length   378 a.a.
NCBI ID   WP_002982186.1    Uniprot ID   A2RGU8
Organism   Streptococcus pyogenes strain 20160179     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1755805..1766941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWK66_RS08790 (PWK66_08740) - 1757029..1758588 (-) 1560 WP_002991352.1 membrane protein -
  PWK66_RS08795 (PWK66_08745) - 1759001..1759306 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  PWK66_RS08800 (PWK66_08750) ruvX 1759318..1759737 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  PWK66_RS08805 (PWK66_08755) - 1759734..1760003 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  PWK66_RS08810 (PWK66_08760) spx 1760116..1760514 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  PWK66_RS08815 (PWK66_08765) recA 1760805..1761941 (-) 1137 WP_002982186.1 recombinase RecA Machinery gene
  PWK66_RS08820 (PWK66_08770) cinA 1762030..1763301 (-) 1272 WP_002991356.1 competence/damage-inducible protein A Machinery gene
  PWK66_RS08825 (PWK66_08775) - 1763370..1763930 (-) 561 WP_002991358.1 DNA-3-methyladenine glycosylase I -
  PWK66_RS08830 (PWK66_08780) ruvA 1763940..1764536 (-) 597 WP_002991359.1 Holliday junction branch migration protein RuvA -
  PWK66_RS08835 (PWK66_08785) - 1764538..1765758 (-) 1221 WP_002991361.1 MFS transporter -

Sequence

Protein


Download         Length: 378 a.a.        Molecular weight: 40646.24 Da        Isoelectric Point: 4.8482

>NTDB_id=792742 PWK66_RS08815 WP_002982186.1 1760805..1761941(-) (recA) [Streptococcus pyogenes strain 20160179]
MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGP
ESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRG
TTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSE
NAKRYLAEHPELFDEIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=792742 PWK66_RS08815 WP_002982186.1 1760805..1761941(-) (recA) [Streptococcus pyogenes strain 20160179]
TTGGCAAAAAAATTAAAAAAGAATGAAGAAATCACTAAGAAGTTTGGTGACGAACGTCGCAAAGCCCTTGATGATGCTTT
GAAAAATATTGAAAAAGATTTTGGTAAGGGCGCAGTGATGCGATTAGGAGAACGTGCAGAGCAAAAAGTTCAGGTTATGA
GTTCAGGAAGTCTAGCTCTTGATATTGCGCTTGGAGCTGGTGGTTATCCTAAAGGACGTATCATCGAAATCTATGGTCCA
GAGTCTTCCGGTAAAACGACTGTGGCTTTACATGCTGTAGCACAAGCTCAAAAAGAAGGTGGAATCGCAGCCTTTATCGA
TGCCGAGCATGCGCTTGATCCAGCTTATGCTGCTGCGCTTGGGGTTAATATTGATGAACTCCTCTTGTCTCAACCAGATT
CTGGAGAACAAGGACTTGAAATTGCAGGTAAATTGATTGATTCTGGTGCGGTTGATCTGGTTGTTGTCGATTCAGTAGCA
GCTTTAGTGCCACGTGCTGAAATTGATGGTGATATTGGCGATAGCCATGTCGGATTGCAAGCACGTATGATGAGTCAGGC
CATGCGTAAATTATCAGCTTCTATTAATAAAACAAAAACTATCGCTATCTTTATTAACCAATTGCGTGAAAAAGTTGGTG
TGATGTTTGGAAATCCTGAAACAACACCAGGTGGTCGAGCTTTGAAATTCTATGCTTCTGTTCGGCTGGATGTGCGTGGA
ACAACTCAAATTAAAGGAACTGGTGACCAAAAGGATAGCAGCATTGGTAAGGAGACCAAAATCAAGGTTGTTAAAAACAA
GGTCGCTCCGCCATTTAAGGTAGCAGAAGTTGAAATCATGTACGGGGAAGGTATTTCTCGTACAGGGGAGCTTGTGAAAA
TTGCTTCTGATTTGGACATTATCCAAAAAGCAGGTGCTTGGTTCTCTTATAATGGTGAGAAGATTGGCCAAGGTTCTGAA
AATGCTAAGCGTTATTTGGCCGAACATCCAGAATTGTTTGATGAAATCGACCGTAAAGTACGTGTTAAATTTGGTTTGCT
TGAAGAAAGCGAAGAAGAATCTGCTATGGCAGTAGCATCAGAAGAAACCGATGATCTTGCTTTAGATTTAGATAATGGTA
TTGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

recA bacterial DNA recombination protein (RecA)

(21-286)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RGU8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Streptococcus pyogenes NZ131

99.206

100

0.992
  recA Streptococcus mutans UA159

87.467

100

0.886
  recA Streptococcus pneumoniae TIGR4

84.935

100

0.865
  recA Streptococcus pneumoniae Rx1

84.935

100

0.865
  recA Streptococcus pneumoniae D39

84.935

100

0.865
  recA Streptococcus pneumoniae R6

84.935

100

0.865
  recA Streptococcus mitis NCTC 12261

85.34

100

0.862
  recA Streptococcus mitis SK321

85.302

100

0.86
  recA Lactococcus lactis subsp. cremoris KW2

79.037

93.386

0.738
  recA Latilactobacillus sakei subsp. sakei 23K

70.326

89.153

0.627
  recA Bacillus subtilis subsp. subtilis str. 168

68.389

87.037

0.595
  recA Acinetobacter baylyi ADP1

60

92.593

0.556
  recA Acinetobacter baumannii D1279779

59.49

93.386

0.556
  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

62.018

89.153

0.553
  recA Neisseria gonorrhoeae MS11

60.641

90.741

0.55
  recA Neisseria gonorrhoeae MS11

60.641

90.741

0.55
  recA Neisseria gonorrhoeae strain FA1090

60.641

90.741

0.55
  recA Vibrio cholerae strain A1552

58.857

92.593

0.545
  recA Vibrio cholerae O1 biovar El Tor strain E7946

58.857

92.593

0.545
  recA Glaesserella parasuis strain SC1401

60.294

89.947

0.542
  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

63.158

85.45

0.54
  recA Pseudomonas stutzeri DSM 10701

57.471

92.063

0.529
  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

59.517

87.566

0.521
  recA Helicobacter pylori 26695

58.383

88.36

0.516
  recA Helicobacter pylori strain NCTC11637

58.383

88.36

0.516
  recA Ralstonia pseudosolanacearum GMI1000

59.621

83.862

0.5