Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   NIL_RS02065 Genome accession   NZ_AP022826
Coordinates   393971..395800 (-) Length   609 a.a.
NCBI ID   WP_187648551.1    Uniprot ID   -
Organism   Nitrosophilus labii strain HRV44     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 388971..400800
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NIL_RS02050 - 391213..391605 (-) 393 WP_187647984.1 sel1 repeat family protein -
  NIL_RS02055 - 391617..393500 (-) 1884 WP_187647985.1 Hpt domain-containing protein -
  NIL_RS02060 - 393497..393910 (-) 414 WP_187647986.1 PAS domain-containing protein -
  NIL_RS02065 uvrC 393971..395800 (-) 1830 WP_187648551.1 excinuclease ABC subunit UvrC Machinery gene
  NIL_RS02070 - 395827..396273 (-) 447 WP_187647987.1 hypothetical protein -
  NIL_RS02075 nadB 396369..397805 (+) 1437 WP_187647988.1 L-aspartate oxidase -
  NIL_RS02080 nhaD 397851..399152 (+) 1302 WP_187647989.1 sodium:proton antiporter NhaD -
  NIL_RS02085 guaA 399193..400743 (+) 1551 WP_187647990.1 glutamine-hydrolyzing GMP synthase -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 70806.70 Da        Isoelectric Point: 10.1485

>NTDB_id=79265 NIL_RS02065 WP_187648551.1 393971..395800(-) (uvrC) [Nitrosophilus labii strain HRV44]
MLQKLKNLPNKPGVYQYFDEKGNILYIGKAKSLKNRVKSYFRFSSTLSPAPNLSPRIYKMISEVENLEYIVVENENDALI
LENSLIKQLKPKYNILLRDDKTYPYIYIDLSEDFPRFEITRKVVKGEKIKYYGPFSTAAKDILDSIYEIFPLVQKSGCLK
GKKACLFYQLKKCLAPCEGKISKDDYALIVQEATKLIIDKKALIKRLENKMLKLSQNLRFEEAAQIRDRIERIKKSEINS
NIDIAKLEDLDIIAIKAQENIAAIVRLFMREGKVISSSSSIIRFDKDKGFDIDEAYKRAILDFYKMESPLVSKKILVGKD
FSQKDEVERLLKDRFDKNISIIYPKRGEKQKLINLAALNAKEIIKKEEKQSEDSILEDIKKLFRLQNTPYRIEIFDNSHL
KGSATVGAMVIFENNKFKKSDYRHYNLTSKDEYSQMKELLQRRCESFEKNSPPDLWIIDGGETLRKLAQEIAKSAGVNLD
IIAISKEKVDFKAYRTKGKAKDIIYTKNDIFKLQPTDKRLQFVQKLRDEAHRFALTFHKKQKIKEDKKISLLKIKGIGKA
KIRRLLNYFGSFENIKEASLEELTTILNKKDALNIKKHFSKDLVNKNML

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=79265 NIL_RS02065 WP_187648551.1 393971..395800(-) (uvrC) [Nitrosophilus labii strain HRV44]
ATGTTGCAAAAACTTAAAAATCTTCCAAACAAACCCGGAGTCTATCAGTATTTCGATGAAAAAGGAAACATTTTATATAT
AGGCAAAGCAAAAAGCTTGAAAAACAGAGTAAAAAGCTATTTTAGATTCTCTTCCACACTATCTCCTGCTCCAAATCTTA
GTCCAAGAATTTACAAAATGATAAGCGAAGTGGAAAATCTGGAATATATCGTAGTTGAAAATGAAAATGACGCGCTTATT
TTGGAAAATTCTCTTATTAAACAGTTAAAACCTAAATACAATATTTTACTAAGAGATGATAAAACTTATCCTTATATATA
CATAGATTTATCTGAGGATTTTCCAAGATTTGAGATCACAAGAAAGGTCGTAAAAGGAGAAAAGATAAAATATTACGGCC
CTTTTTCGACCGCTGCCAAAGATATATTAGATTCAATCTATGAGATTTTTCCTCTGGTTCAAAAAAGCGGCTGTCTTAAA
GGAAAAAAAGCGTGTCTTTTTTATCAGTTGAAAAAATGTCTAGCTCCTTGCGAAGGAAAAATAAGCAAAGATGATTATGC
TTTAATAGTCCAAGAAGCAACAAAACTCATAATAGATAAAAAAGCATTGATAAAGAGATTAGAGAACAAAATGCTAAAAC
TATCCCAAAATCTTAGATTTGAAGAGGCGGCACAGATAAGAGATAGAATCGAAAGAATCAAAAAGAGCGAAATAAACAGT
AACATAGATATCGCAAAGCTTGAAGATTTAGATATCATAGCAATTAAAGCCCAAGAGAATATTGCAGCTATAGTTAGACT
TTTTATGAGAGAAGGCAAAGTTATTTCAAGCTCATCTTCGATAATAAGATTTGACAAAGACAAAGGTTTCGATATAGACG
AAGCCTATAAAAGAGCCATATTAGATTTTTATAAAATGGAGTCGCCGTTGGTTTCTAAAAAGATATTGGTAGGTAAAGAT
TTTAGTCAAAAAGATGAGGTAGAACGGCTTTTAAAAGATAGATTTGATAAAAACATCTCCATCATATATCCAAAAAGAGG
CGAAAAACAAAAACTAATAAACCTTGCCGCTTTAAACGCAAAAGAGATTATAAAAAAAGAGGAAAAACAGAGCGAAGATT
CTATATTGGAAGATATCAAAAAACTTTTTAGACTCCAAAACACCCCTTACAGAATCGAAATTTTTGATAATTCTCATTTA
AAAGGAAGCGCTACTGTTGGAGCAATGGTCATCTTTGAAAACAATAAATTCAAAAAAAGTGACTACAGGCACTATAATCT
AACTTCTAAAGATGAGTATTCTCAGATGAAAGAACTGCTTCAAAGAAGATGCGAAAGTTTTGAAAAAAACTCTCCACCAG
ATCTTTGGATAATAGACGGTGGAGAAACTTTAAGAAAACTTGCCCAAGAAATAGCAAAAAGTGCAGGAGTCAATTTGGAC
ATTATCGCCATCTCTAAAGAAAAAGTAGATTTTAAAGCATATAGAACTAAAGGTAAAGCAAAAGATATAATATATACCAA
AAATGATATTTTTAAACTTCAGCCAACCGATAAAAGATTGCAATTTGTACAAAAACTAAGAGATGAAGCTCATAGATTTG
CGTTAACATTTCATAAAAAACAGAAAATAAAAGAGGACAAAAAAATATCTCTTTTAAAAATAAAGGGTATTGGCAAAGCC
AAGATAAGAAGACTATTAAACTATTTTGGAAGCTTCGAAAATATAAAAGAAGCCTCGCTGGAAGAACTCACTACTATTTT
AAATAAAAAAGACGCTTTAAATATAAAAAAACATTTTTCTAAAGATTTAGTTAATAAAAATATGTTATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix domain (HHH_5)

(550-596)

UvrB/uvrC motif (UVR)

(201-235)

GIY-YIG catalytic domain (GIY-YIG)

(12-94)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(381-534)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

53.885

97.209

0.524

Multiple sequence alignment