Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7644_RS00275 Genome accession   NZ_CP131645
Coordinates   52238..55387 (-) Length   1049 a.a.
NCBI ID   WP_341931113.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 2004S05-027     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47238..60387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7644_RS00245 (Q7644_00240) - 47274..47807 (-) 534 WP_003692498.1 hypothetical protein -
  Q7644_RS00250 (Q7644_00245) - 48169..48300 (-) 132 WP_283957972.1 hypothetical protein -
  Q7644_RS00255 (Q7644_00250) - 48417..48863 (-) 447 WP_082279145.1 hypothetical protein -
  Q7644_RS00260 (Q7644_00255) - 49091..49480 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  Q7644_RS00265 (Q7644_00260) - 49738..50022 (-) 285 WP_003687282.1 VOC family protein -
  Q7644_RS00270 (Q7644_00265) carA 50076..51209 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  Q7644_RS00275 (Q7644_00270) pilC 52238..55387 (-) 3150 WP_341931113.1 PilC family type IV pilus tip adhesin Machinery gene
  Q7644_RS00280 (Q7644_00275) - 56002..56133 (-) 132 WP_341931114.1 hypothetical protein -
  Q7644_RS00285 (Q7644_00280) - 56283..56414 (-) 132 WP_341931115.1 hypothetical protein -
  Q7644_RS00290 (Q7644_00285) - 56564..56695 (-) 132 WP_341931115.1 hypothetical protein -
  Q7644_RS00295 (Q7644_00290) - 56812..57258 (-) 447 WP_082279145.1 hypothetical protein -
  Q7644_RS00300 (Q7644_00295) - 57407..57538 (-) 132 WP_341931116.1 hypothetical protein -
  Q7644_RS00305 (Q7644_00300) - 57688..57942 (-) 255 WP_134797834.1 hypothetical protein -
  Q7644_RS00310 (Q7644_00305) apbC 57968..59047 (-) 1080 WP_047918675.1 iron-sulfur cluster carrier protein ApbC -
  Q7644_RS00320 (Q7644_00315) - 59421..59930 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -

Sequence

Protein


Download         Length: 1049 a.a.        Molecular weight: 115209.31 Da        Isoelectric Point: 9.9018

>NTDB_id=789936 Q7644_RS00275 WP_341931113.1 52238..55387(-) (pilC) [Neisseria gonorrhoeae strain 2004S05-027]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGAMAQTSNYAIIMNERKQPEVKWEGQYNQSALKDKSRERTFSHTSQKNSLG
RTSNFISFNNNDTLVSQQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIRTTRAGLAGYAYTGIRCGHARDCPKL
TYKTQFSFDNPDLAKTGDRLDRHTEPSRDNSPIYKLKDYPWLGVSFNLGAEGTAKDGRSSSRLISSFNEKNSNNNLVYTT
EGRDISLGNWQSESTAVAYYLNAKLHLLDKKEIKDITGKTVQLGVLKPSIDVKTQNTGFAGLLNFWSKWDIKDNGQIPVK
LGLPEVKAGHCTNKPNPNPKSKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPGRPGRYSL
AALNAQDIKSREPNFNSRQTVIRLPGGVYRIAPTRDRIVGLNGNDGKNDTFGIYKERLVTPDADEWAKVLLPWTVRYYGN
DDIFKTFNQPNSKTQNGKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATSANDGMVHLFKRNGTDQRGYELK
LSYIPGTMERKDIEGNDSDLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLSKID
SSNLTGVSMFDVQNDKNNNKNDNNRVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKDINSNDNKTALYVYDLENGSGSLI
KKIEAPSGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSDSNPSKWSVSTIFEGQRPITSAPAVSRLADKRVVIF
GTGSDLSESDVFNTDEQYIYGIFDDDKANVSVKVKDHMGDGLLKQNLTQENKTLFLTNNKASGGSADKGWVVKLREGERV
TVKPTVVLRTAFVTIRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPDHNSVAQYSGHKKTSKGKSIPIGCMGKGG
KTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGIK
RLSWREVFF

Nucleotide


Download         Length: 3150 bp        

>NTDB_id=789936 Q7644_RS00275 WP_341931113.1 52238..55387(-) (pilC) [Neisseria gonorrhoeae strain 2004S05-027]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCAGTAACTACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGAGG
GTCAATATAATCAATCAGCATTAAAGGACAAAAGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAAACAGCCTCGGC
AGGACAAGCAATTTTATCTCATTCAACAATAACGATACCCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGC
CACCTACCTGCCGCCCTACGGCAAGGTTTCCGGCTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATTGGA
TTCGTACCACCCGGGCCGGGCTGGCAGGCTACGCCTACACCGGTATCCGTTGCGGACATGCCCGAGACTGTCCCAAACTT
ACCTATAAAACCCAATTTTCCTTCGATAATCCCGACTTGGCAAAAACAGGAGACAGGCTGGATAGGCACACAGAGCCAAG
CCGCGACAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCG
CCAAAGATGGCAGATCATCCAGCAGATTGATATCTTCTTTTAATGAAAAGAATAGTAATAACAACCTCGTCTATACCACG
GAAGGCCGCGATATTTCCTTGGGCAACTGGCAGAGCGAAAGTACCGCCGTGGCCTATTATCTGAACGCCAAGCTGCACCT
GCTGGACAAAAAAGAGATTAAAGATATCACCGGCAAAACAGTGCAGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGA
CACAAAATACGGGGTTTGCCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAG
CTCGGCCTGCCGGAAGTCAAAGCCGGGCACTGCACCAACAAACCGAACCCCAATCCCAAATCCAAAGCCCCTTCGCCGGC
ACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACC
CCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGGCAGGCCCGGCCGGTATTCCCTC
GCCGCTTTGAATGCGCAGGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCCGATTGCCGGGCGG
CGTGTACCGGATCGCCCCGACTCGCGACAGGATCGTGGGTTTGAATGGCAATGACGGCAAAAACGACACTTTCGGCATCT
ACAAGGAAAGGTTAGTCACACCTGATGCCGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTACGGTAAT
GACGATATATTTAAAACATTCAACCAACCAAACAGCAAAACACAAAACGGCAAAAAACAATACAGCCAAAAATACCGCAT
CCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGCGGTCGGCGGGT
ATCTGGCAACTTCTGCCAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACGAGGCTACGAACTGAAG
CTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGCAATGACTCCGACCTCGCCAAAGAGCTGCGCACCTT
TGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACA
AGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTGGGCGGCAGAGGCGCGTATGCCTTGGATTTAAGCAAAATCGAC
AGCAGCAACCTGACCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAAGAATGACAATAATCGCGTGAA
ATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATG
CGGCTAAAGACATTAACAGCAACGACAATAAAACCGCGCTGTATGTGTATGATTTGGAAAACGGCAGTGGTAGTCTGATT
AAAAAAATCGAAGCACCCAGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACAGTCGA
TATCGCCTATGCCGGCGACCGGGGCGGGAATATGTACCGCTTTGATTTGAGCGATTCCAATCCTAGTAAATGGTCTGTAA
GCACTATTTTCGAAGGCCAGAGGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTCGTTATCTTC
GGTACGGGCAGCGATTTGAGTGAAAGTGACGTATTCAATACGGACGAACAATATATTTACGGTATCTTTGACGACGATAA
GGCGAATGTTAGTGTAAAGGTAAAAGACCACATGGGCGACGGGCTGCTCAAGCAAAACCTTACGCAGGAAAATAAAACCT
TGTTCCTGACAAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTGAGGGAAGGAGAACGCGTT
ACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTCACCATCCGCAGCTATACGGGTAATGACAAATGCGGCGCGCA
AACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATCACA
ATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCTCCAAAGGCAAATCCATCCCTATAGGTTGTATGGGAAAAGGCGGT
AAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGATTT
CCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCT
TCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAA
CGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterProScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(520-860)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

69.536

100

0.701