Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7647_RS10230 Genome accession   NZ_CP131636
Coordinates   1931780..1934875 (+) Length   1031 a.a.
NCBI ID   WP_341944618.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 2016E02-233     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1926780..1939875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7647_RS10210 (Q7647_10270) - 1927477..1927926 (-) 450 WP_003692085.1 CopD family copper resistance protein -
  Q7647_RS10215 (Q7647_10275) waaA 1927967..1929238 (-) 1272 WP_341944617.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  Q7647_RS10220 (Q7647_10280) gnd 1929301..1930749 (-) 1449 WP_003688061.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  Q7647_RS10225 (Q7647_10285) - 1930829..1931092 (-) 264 WP_017147189.1 hypothetical protein -
  Q7647_RS10230 (Q7647_10290) pilC 1931780..1934875 (+) 3096 WP_341944618.1 PilC family type IV pilus tip adhesin Machinery gene
  Q7647_RS10235 (Q7647_10295) - 1935528..1935812 (+) 285 WP_003692093.1 GIY-YIG nuclease family protein -
  Q7647_RS10240 (Q7647_10300) yccS 1936296..1938446 (-) 2151 WP_003697785.1 YccS family putative transporter -
  Q7647_RS10245 (Q7647_10305) - 1938563..1939790 (-) 1228 Protein_1991 PilT/PilU family type 4a pilus ATPase -

Sequence

Protein


Download         Length: 1031 a.a.        Molecular weight: 112890.14 Da        Isoelectric Point: 9.7096

>NTDB_id=789785 Q7647_RS10230 WP_341944618.1 1931780..1934875(+) (pilC) [Neisseria gonorrhoeae strain 2016E02-233]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGGAMAQTHQYAIIMNVRNQPEVKQNVPSSIKDKDRRREYTYYTHRTGGGSV
SFNNNDTLVSQQSGTAVFGTATYLPPYGKVSGFDADALKERNNAVDWIRTTRIALAGYSYIDVICRSYTGCPKLVYKTRF
TFGQQGLKRKAGSKLDIYEDKSRENSPIYKLSDYPWLGVSFNLGSENTVQNSKLFNKLISSFREGNNNQTIVSTTEGNPI
SLGDRQREHTAVAYYLNAKLHLLDKKGIEDIAQGKIVDLGILKPHVETTGRSLLDFWARWDIKDTGQIPVKLGLPQVKAG
RCTNKPNPNNNTKAPSPALTAPALWFGPGQDGKAEMYSASVSTYPDSSSSRIFLQELKTQTEPGKPGRYSLKSLNDGEIK
SRQPSFNGRQTIIRLDDGVHLIKLNGSKDEVAAFVNLNGNNTGKNDTFGIVKEANVNLDADEWKKVLLPWTVRGPDNDNK
FKSINQKPEKYSQRYRIRDNNGNRDLGDIVNSPIVAVGGYLATAANDGMVHIFKKNGGSDERSYNLKLSYIPGTMPRKDI
QSQESTLAKELRAFAEKGYVGDRYGVDGGFVLRQVELSGQKHVFMFGAMGFGGRGAYALDLSKINGNYPAAAPLFDVKDG
DNNGKNRVKVELGYTVGTPQIGKIRNGKYAAFLASGYAAKKIDDSTNKTALYVYDLKDTLGTPIAKIEVKDGKGGLSSPT
LVDKDLDGTVDIAYAGDRGGNMYRFDLSDSNPDKWSVRTIFEGDKPITSAPAVSRLADKRVVIFGTGSDLTEDDVLNTGE
QYIYGIFDDDKGTVKVTVQNGTGGGLLEQVLSEENKTLFLNKRSDGSNGKGWVVRLREGERVTVKPTVVLRTAFVTIRKY
TDTDKCGAQTAILGINTADGGALTPRSARPIVPDHNSVAQYSGHKTTSKGKSIPIGCMDKDGKTVCPNGYVYDKPVNVRY
LDETETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3096 bp        

>NTDB_id=789785 Q7647_RS10230 WP_341944618.1 1931780..1934875(+) (pilC) [Neisseria gonorrhoeae strain 2016E02-233]
ATGAATAAAACTTTGAAACGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGGGGCGATGGCGCAAACCCATCAATACGCTATTATCATGAACGTGCGAAACCAGCCCGAGGTAAAGCAGA
ATGTGCCATCTTCAATAAAGGACAAAGACAGGAGGCGCGAATATACTTATTATACGCACAGAACAGGAGGAGGCTCTGTC
TCATTCAACAATAACGATACCCTTGTTTCCCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTA
CGGCAAGGTTTCCGGTTTTGATGCCGACGCTCTGAAAGAGCGCAACAATGCCGTTGATTGGATTCGTACCACCCGCATCG
CGCTGGCAGGCTACTCCTACATCGACGTCATATGCAGAAGCTACACAGGCTGTCCCAAACTTGTCTATAAAACCCGATTT
ACCTTCGGTCAACAAGGGTTGAAAAGAAAGGCAGGCAGCAAGCTGGATATATACGAAGACAAAAGCCGCGAAAATTCGCC
CATTTACAAATTGTCGGATTATCCTTGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGAATACCGTCCAAAATAGCAAAT
TATTCAACAAATTGATATCTTCTTTTAGAGAAGGCAATAATAATCAAACCATCGTCTCTACGACAGAAGGCAACCCTATT
TCCCTTGGCGACCGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGG
GATTGAAGATATCGCCCAAGGCAAAATAGTGGATTTGGGTATCTTGAAACCGCACGTCGAGACGACAGGACGAAGCTTGC
TAGATTTTTGGGCTAGGTGGGACATTAAAGATACCGGGCAGATTCCGGTCAAGCTCGGCCTGCCGCAAGTCAAAGCAGGC
CGCTGCACCAACAAACCGAACCCCAATAATAATACCAAAGCCCCTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTTCGG
ACCCGGGCAAGATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTTCC
TCCAAGAGCTGAAAACTCAAACCGAACCCGGCAAACCCGGCCGCTATTCCCTCAAATCTTTGAATGATGGTGAGATTAAA
AGTCGACAGCCGAGTTTCAACGGGCGGCAAACAATCATCCGATTGGATGACGGCGTACATTTGATCAAACTGAATGGAAG
CAAGGATGAGGTCGCCGCTTTTGTCAATTTAAATGGAAACAACACCGGCAAAAACGACACTTTCGGCATTGTTAAGGAAG
CGAACGTCAATCTTGACGCCGACGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTCCCGATAATGACAATAAA
TTTAAATCAATTAACCAAAAACCAGAAAAATACAGCCAAAGATACCGCATCCGCGACAACAACGGCAATCGCGATTTGGG
CGACATCGTCAACAGCCCGATTGTCGCGGTCGGCGGGTATTTGGCAACCGCCGCGAACGACGGGATGGTGCATATCTTCA
AAAAAAACGGCGGCAGTGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCAAGGATATT
CAAAGCCAAGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGA
CGGCGGCTTTGTCTTGCGCCAAGTCGAACTGAGCGGGCAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTTGGCGGCA
GGGGCGCGTATGCCTTGGATTTAAGCAAAATCAACGGAAATTATCCGGCCGCCGCCCCCCTGTTTGATGTCAAAGATGGC
GATAATAACGGCAAAAATCGCGTGAAAGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAATCCGCAACGG
CAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAAAAAATTGACGACTCAACAAATAAAACCGCGCTGTATGTAT
ATGATTTGAAAGACACCTTAGGTACGCCGATTGCAAAAATCGAAGTGAAGGACGGCAAAGGCGGGCTTTCGTCCCCCACG
CTGGTGGATAAAGATTTGGACGGCACAGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTT
GAGCGATTCCAATCCTGATAAATGGTCTGTAAGGACTATTTTCGAAGGCGACAAGCCGATTACTTCCGCGCCCGCCGTTT
CCCGACTGGCAGACAAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGACCGAAGATGATGTACTGAATACGGGCGAA
CAATATATTTACGGTATCTTTGACGACGATAAGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGTTGCT
CGAGCAAGTGCTTAGCGAGGAAAATAAAACATTATTCCTGAACAAGAGATCCGACGGATCGAACGGCAAAGGGTGGGTAG
TGAGATTGAGGGAAGGAGAACGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTGACCATCCGGAAATAT
ACGGATACGGACAAATGTGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAG
CGCGCGCCCGATTGTGCCGGATCACAATTCGGTTGCGCAATATTCCGGCCATAAGACAACCTCCAAAGGCAAATCCATCC
CTATAGGTTGTATGGACAAAGACGGTAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGTTAT
CTGGATGAAACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAG
GCGTCCCGGCAAAAACAACCGCTGCTTCTCCAAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATA
TTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterProScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(506-841)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

74.809

100

0.76