Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7647_RS00275 Genome accession   NZ_CP131636
Coordinates   52970..56134 (-) Length   1054 a.a.
NCBI ID   WP_341944625.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 2016E02-233     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47970..61134
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7647_RS00255 (Q7647_00250) - 49555..49944 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  Q7647_RS00260 (Q7647_00255) - 50107..50274 (-) 168 WP_003687280.1 glyoxalase -
  Q7647_RS00265 (Q7647_00260) - 50202..50486 (-) 285 WP_003687282.1 VOC family protein -
  Q7647_RS00270 (Q7647_00265) carA 50540..51673 (-) 1134 WP_003700860.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  Q7647_RS00275 (Q7647_00270) pilC 52970..56134 (-) 3165 WP_341944625.1 PilC family type IV pilus tip adhesin Machinery gene
  Q7647_RS00280 (Q7647_00275) apbC 57545..58624 (-) 1080 WP_003699443.1 iron-sulfur cluster carrier protein ApbC -
  Q7647_RS00290 (Q7647_00285) - 58998..59507 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  Q7647_RS00295 (Q7647_00290) nadR 59848..60288 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  Q7647_RS00300 (Q7647_00295) hpaC 60403..60903 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1054 a.a.        Molecular weight: 115913.10 Da        Isoelectric Point: 9.8877

>NTDB_id=789725 Q7647_RS00275 WP_341944625.1 52970..56134(-) (pilC) [Neisseria gonorrhoeae strain 2016E02-233]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGQAQAQTYKYAIVMNERKQPEVKWESQYNQSALKDKGRERTFSHTSQKNRF
GITSNFISFNNNDELVSQQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIHTTRPGLAGYGYDGIRCGSAQDCPK
LTYKTRFSFDNPDLVKTRGGLDRHTEPSRENSPIYKLKDHPWLGVSFNLGGEGTAKDGRSSSKLVSSFDENNSNSNQNLV
YTTEGHRISLGNWQRETTAMAYYLNAKLHLLDKKQIKDIAQGKTVRLGVLKPSIDVKTQNTGLSGLLNFWSKWDIKDNGQ
IPVKLGLPQVKAVRCTNTAHPNKTAQAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPG
RHSLAALDTQNIKSREPNFNSRQTVIRLPGGVYKINPGKNGGRVAGINGNDGKNDTFGIFKDRYVTPETDEWSEVLLPWT
ARYYGNDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPIVAVGGYLATAANDGMVHIFKKNGGSD
ERSYNLKLSYIPGTMPRKDIQSQESTLAKELRAFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYA
LDLSKIDSSNLTGVSMFDVQNDKNNNKNDNNRVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKDINSNDNKTALYVYDLE
NGSGSLIKKIEAPSGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSDSNPDKWSVRTIFEGDKPITSAPAVSRLA
DKRVVIFGTGSDLTEDDVLNTGEQYIYGIFDDDKGTVKVTVQNGTGGGLLEQVLSEENKTLFLNKRSDGSNGKGWVVRLR
EGERVTVKPTVVLRTAFVTIRKYTDTDKCGAQTAILGINTADGGALTPRSARPIVPEANKDVAQYSGHKTAGGKSVPIGC
MWKNSKTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGP
MCGIKRLSWREVFF

Nucleotide


Download         Length: 3165 bp        

>NTDB_id=789725 Q7647_RS00275 WP_341944625.1 52970..56134(-) (pilC) [Neisseria gonorrhoeae strain 2016E02-233]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGCAGGCGCAGGCGCAAACGTATAAATACGCTATTGTGATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGG
AGAGTCAATATAATCAATCAGCATTAAAGGACAAAGGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAAACAGATTC
GGCATCACAAGCAATTTTATCTCATTCAACAATAACGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCAC
AGCCACCTACCTGCCGCCCTACGGCAAGGTTTCCGGCTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATT
GGATTCATACCACCCGGCCCGGGCTGGCAGGCTACGGCTACGACGGTATCCGTTGCGGAAGTGCCCAAGACTGTCCCAAA
CTTACCTATAAAACCCGATTTTCCTTCGATAATCCCGACTTGGTAAAAACAAGAGGCGGGCTGGATAGGCACACAGAGCC
AAGCCGCGAAAATTCGCCCATTTACAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGGCGAGGGTA
CCGCCAAAGATGGCAGATCATCCAGCAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTC
TATACGACAGAAGGCCACCGTATTTCCCTTGGCAACTGGCAGCGCGAAACGACCGCCATGGCCTATTATCTGAACGCCAA
GCTGCACCTGCTGGACAAAAAACAGATTAAAGATATCGCCCAAGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCA
TCGATGTGAAGACACAAAATACGGGGCTTAGCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAG
ATTCCGGTCAAGCTCGGCCTGCCGCAAGTCAAAGCCGTGCGCTGCACCAACACCGCCCACCCCAATAAAACAGCCCAAGC
CCCTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGG
TTTCCACCTACCCCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGC
CGGCATTCCCTCGCCGCTTTGGATACGCAGAACATCAAAAGCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCG
ATTGCCGGGCGGCGTGTACAAGATCAACCCGGGCAAGAACGGCGGCCGGGTCGCGGGTATTAATGGCAATGACGGCAAAA
ACGACACTTTCGGCATCTTCAAGGACAGGTATGTCACACCTGAGACCGACGAGTGGAGCGAAGTGCTGCTGCCTTGGACG
GCCCGGTATTACGGTAATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATA
CAGCCAAAAATACCGCATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGA
TTGTCGCGGTCGGCGGGTATTTGGCAACCGCCGCGAACGACGGGATGGTGCATATCTTCAAAAAAAACGGCGGCAGTGAT
GAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCAAGGATATTCAAAGCCAAGAATCCACCCT
TGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCC
GCATTACAGATGACCAAGACAAGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTTGGCGGCAGAGGCGCGTATGCC
TTGGATTTAAGCAAAATCGACAGCAGCAACCTGACCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAA
GAATGACAATAATCGCGTGAAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCG
CCTTCCTCGCCTCCGGTTATGCGGCTAAAGACATTAACAGCAACGACAATAAAACCGCGCTGTATGTGTATGATTTGGAA
AACGGCAGTGGTAGTCTGATTAAAAAAATCGAAGCACCCAGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAA
AGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCGATTCCA
ATCCTGATAAATGGTCTGTAAGGACTATTTTCGAAGGCGACAAGCCGATTACTTCCGCGCCCGCCGTTTCCCGACTGGCA
GACAAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGACCGAAGATGATGTACTGAATACGGGCGAACAATATATTTA
CGGTATCTTTGACGACGATAAGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGTTGCTCGAGCAAGTGC
TTAGCGAGGAAAATAAAACATTATTCCTGAACAAGAGATCCGACGGATCGAACGGCAAAGGGTGGGTAGTGAGATTGAGG
GAAGGAGAACGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTGACCATCCGGAAATATACGGATACGGA
CAAATGTGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGA
TTGTGCCGGAAGCCAATAAGGATGTCGCACAATATTCCGGCCATAAGACAGCCGGCGGCAAGTCCGTCCCCATAGGCTGC
ATGTGGAAAAACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGCTACCTGGACGAAAA
GAAAACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCC
GCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCG
ATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterProScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(526-864)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

70.782

100

0.713