Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   PUW68_RS04380 Genome accession   NZ_CP118060
Coordinates   882262..882978 (-) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain VSI35     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 877262..887978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW68_RS04360 (PUW68_04360) - 877302..878546 (+) 1245 WP_070581829.1 ammonium transporter -
  PUW68_RS04365 (PUW68_04365) - 878647..879606 (+) 960 WP_070844229.1 LacI family DNA-binding transcriptional regulator -
  PUW68_RS04370 (PUW68_04370) - 879691..881175 (+) 1485 WP_011275299.1 sucrose-6-phosphate hydrolase -
  PUW68_RS04375 (PUW68_04375) - 881179..882144 (+) 966 WP_011275300.1 carbohydrate kinase -
  PUW68_RS04380 (PUW68_04380) agrA 882262..882978 (-) 717 WP_011275301.1 LytTR family DNA-binding domain-containing protein Regulator
  PUW68_RS04385 (PUW68_04385) - 882997..884280 (-) 1284 WP_070581833.1 GHKL domain-containing protein -
  PUW68_RS04390 (PUW68_04390) - 884307..884447 (-) 141 WP_053017473.1 cyclic lactone autoinducer peptide -
  PUW68_RS04395 (PUW68_04395) - 884450..885016 (-) 567 WP_070581835.1 accessory gene regulator AgrB -
  PUW68_RS04400 (PUW68_04400) - 885746..886531 (-) 786 WP_070581837.1 carbon-nitrogen family hydrolase -
  PUW68_RS04405 (PUW68_04405) - 886724..887347 (-) 624 WP_070440204.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=789710 PUW68_RS04380 WP_011275301.1 882262..882978(-) (agrA) [Staphylococcus haemolyticus strain VSI35]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=789710 PUW68_RS04380 WP_011275301.1 882262..882978(-) (agrA) [Staphylococcus haemolyticus strain VSI35]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGTGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCT
ATTGGAAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCAATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACACACTCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAAACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGATTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAACAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCGGTTCGTAATGTTAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878