Detailed information NTG0789659

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: PUW49_RS02380
• Genome accession: NZ_CP118054
• Coordinates: 466471..467526 (+)
• Length: 351 a.a.
• NCBI ID: WP_024052081.1
• Uniprot ID: A0A413KQY5
• Organism: Streptococcus anginosus strain VSI37
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 461471..472526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW49_RS02350 (PUW49_02350)	-	461991..462626 (-)	636	WP_024052085.1	YigZ family protein	-
PUW49_RS02355 (PUW49_02355)	comFA/cflA	462683..463984 (+)	1302	WP_024052084.1	DEAD/DEAH box helicase	Machinery gene
PUW49_RS02360 (PUW49_02360)	comFC/cflB	463981..464646 (+)	666	WP_024052083.1	ComF family protein	Machinery gene
PUW49_RS02365 (PUW49_02365)	raiA	464724..465266 (+)	543	WP_003025754.1	ribosome-associated translation inhibitor RaiA	-
PUW49_RS02370 (PUW49_02370)	rsmD	465455..466003 (+)	549	WP_171021853.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
PUW49_RS02375 (PUW49_02375)	coaD	465993..466490 (+)	498	WP_021001374.1	pantetheine-phosphate adenylyltransferase	-
PUW49_RS02380 (PUW49_02380)	sepM	466471..467526 (+)	1056	WP_024052081.1	SepM family pheromone-processing serine protease	Regulator
PUW49_RS02385 (PUW49_02385)	-	467665..468228 (+)	564	WP_024052080.1	YutD-like domain-containing protein	-
PUW49_RS02390 (PUW49_02390)	rlmN	468269..469351 (+)	1083	WP_024052079.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
PUW49_RS02395 (PUW49_02395)	-	469344..469874 (+)	531	WP_024052078.1	VanZ family protein	-
PUW49_RS02400 (PUW49_02400)	trpB	470235..471443 (+)	1209	Protein_432	tryptophan synthase subunit beta	-
PUW49_RS02405 (PUW49_02405)	cclA/cilC	471604..472263 (-)	660	WP_024052075.1	A24 family peptidase	Machinery gene

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38290.25 Da
• Isoelectric Point: 10.1906

>NTDB_id=789659 PUW49_RS02380 WP_024052081.1 466471..467526(+) (sepM) [Streptococcus anginosus strain VSI37]
MEKPRNKFKKWPIIAVVGVILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATLAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKELIDYVGAQKIGSKVKVNYVEDGQKKSATGKIIKLENGKNGIGISLIDRTEVTSNTPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide

• Length: 1056 bp

>NTDB_id=789659 PUW49_RS02380 WP_024052081.1 466471..467526(+) (sepM) [Streptococcus anginosus strain VSI37]
ATGGAAAAACCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAGTAGTAGGGGTGATTTTGCTTTTCTTATCTTTTGT
AGTTCCCTTGCCTTATTATATTGAGGTGCCAGGTGGTGCAGCGGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTATAATTTTGTAACGGTTGGAATTCAGCATGCGACCCTCGCTCATTTGGTTTATGCTTGGCTG
ACACCTTTTACGGATATTTATTCGGCGAAGGATTTGACTGGTGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACGTCGCAAAACCTAGCTAAATACCAAGGGTTGAAAAAAGCTGGCAAAGACATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGTATTTTAAATATTGCAGATACCGTGACAGGTGTGAAT
GATAAGACTTTCAATAGTTCAAAAGAATTGATAGACTATGTCGGAGCGCAAAAGATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAGAAGTCTGCTACAGGTAAAATTATTAAACTTGAAAATGGGAAAAACGGGATTGGCATTAGTT
TGATTGACCGAACAGAAGTCACAAGCAACACACCAATTGAATTTTCAACTGCCGGTATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACGCAAATTGCAGATCCAACATTGAGAGACGGCAGAAATATTGCTGGGACAGGTTCGAT
TGACCGAGAAGGAAAAGTTGGCGACATTGGTGGGATTGACAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTCACCAAGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAACTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAGAG
CACAAAAAAGTCGTAA

Domains

Predicted by InterProScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (234-307)

• PDZ domain (PDZ_2) (133-197)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	64.223	97.151	0.624