Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7650_RS00275 Genome accession   NZ_CP131626
Coordinates   52944..56099 (-) Length   1051 a.a.
NCBI ID   WP_341978900.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 2020S05-258     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47944..61099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7650_RS00255 (Q7650_00250) - 49864..50253 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  Q7650_RS00260 (Q7650_00255) - 50416..50583 (-) 168 WP_003687280.1 glyoxalase -
  Q7650_RS00265 (Q7650_00260) - 50511..50795 (-) 285 WP_003687282.1 VOC family protein -
  Q7650_RS00270 (Q7650_00265) carA 50849..51982 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  Q7650_RS00275 (Q7650_00270) pilC 52944..56099 (-) 3156 WP_341978900.1 PilC family type IV pilus tip adhesin Machinery gene
  Q7650_RS00280 (Q7650_00275) apbC 57509..58588 (-) 1080 WP_235219848.1 iron-sulfur cluster carrier protein ApbC -
  Q7650_RS00290 (Q7650_00285) - 58962..59471 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  Q7650_RS00295 (Q7650_00290) nadR 59812..60252 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  Q7650_RS00300 (Q7650_00295) hpaC 60367..60867 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1051 a.a.        Molecular weight: 115460.65 Da        Isoelectric Point: 9.8554

>NTDB_id=789512 Q7650_RS00275 WP_341978900.1 52944..56099(-) (pilC) [Neisseria gonorrhoeae strain 2020S05-258]
MNKTLKRRVFRHTALYAAILMFSHTGGGGQAQAQTYKYAIVMNERKQPEVKWESQYNQSALKDKGRERTFSHTSQKNRFG
ITSNFISFNNNDELVSQQSGTAVFGTATYLPPYGKVSGFDTDRLKERANAAGWIRTTRPGLAGYGYDGIRCGSAQDCPKL
TYKTRFSFDNPDLVKTRGGLDRHTEPSRENSPIYKLKDHPWLGVSFNLGGEGTAKDGRSSSKLVSSFDENNSNSNQNLVY
TTEGHRISLGNWQRETTAMAYYLNAKLHLLDKKQIKDIAQGKTVRLGVLKPSIDVKTQNTGLSGLLNFWSKWDIKDNGQI
PVKLGLPQVKAVRCTNTAHPNKTAQAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPGR
HSLAALDTQNIKSREPNFNSRQTVIRLPGGVYKINPGKNGGRVAGINGNDGKNDTFGIFKDRYVTPETDEWSEVLLPWTA
RYYGNDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPIVAVDGYLATSANDGMVHIFKKTGTDER
SYNLKLSYIPGTMERKDIEGNDSDLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALD
LSKINGNYPAAAPLFDVKDGDNNGKNRVKVELGYTVGTPQIGKTQNGKYAAFLASGYAAKDINSNDNKTALYVYDLENGS
GSLIKKIEAPSGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSNSDPSKWSVSTIFEGGKPITSAPAVSRLADKR
VVIFGTGSDLSEEDVVGTNPQYIYGIFDDDKGTVKVTVQNGTGGGLLEQVLSEENKTLFLNKRSDGSNGKGWVVRLREGE
RVTVKPTVVLRTAFVTIRKYTDTDKCGAQTAILGINTADGGALTPRSARPIVPEANKDVAQYSGHKTAGGKSVPIGCMWK
NSKTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCG
IKRLSWREVFF

Nucleotide


Download         Length: 3156 bp        

>NTDB_id=789512 Q7650_RS00275 WP_341978900.1 52944..56099(-) (pilC) [Neisseria gonorrhoeae strain 2020S05-258]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGCAGGCGCAGGCGCAAACGTATAAATACGCTATTGTGATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGAGA
GTCAATATAATCAATCAGCATTAAAGGACAAAGGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAAACAGATTCGGC
ATCACAAGCAATTTTATCTCATTCAACAATAACGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGC
CACCTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGGCTGAAAGAGCGCGCCAATGCCGCCGGTTGGA
TTCGTACCACCCGGCCCGGGCTGGCAGGCTACGGCTACGACGGTATCCGTTGCGGAAGTGCCCAAGACTGTCCCAAACTT
ACCTATAAAACCCGATTTTCCTTCGATAATCCCGACTTGGTAAAAACAAGAGGCGGGCTGGATAGGCACACAGAGCCAAG
CCGCGAAAATTCGCCCATTTACAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGGCGAGGGTACCG
CCAAAGATGGCAGATCATCCAGCAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTCTAT
ACGACAGAAGGCCACCGTATTTCCCTTGGCAACTGGCAGCGCGAAACGACCGCCATGGCCTATTATCTGAACGCCAAGCT
GCACCTGCTGGACAAAAAACAGATTAAAGATATCGCCCAAGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCG
ATGTGAAGACACAAAATACGGGGCTTAGCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATT
CCGGTCAAGCTCGGCCTGCCGCAAGTCAAAGCCGTGCGCTGCACCAACACCGCCCACCCCAATAAAACAGCCCAAGCCCC
TTCGCCGGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGGTTT
CCACCTACCCCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGCCGG
CATTCCCTCGCCGCTTTGGATACGCAGAACATCAAAAGCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCGATT
GCCGGGCGGCGTGTACAAGATCAACCCGGGCAAGAACGGCGGCCGGGTCGCGGGTATTAATGGCAATGACGGCAAAAACG
ACACTTTCGGCATCTTCAAGGACAGGTATGTCACACCTGAGACCGACGAGTGGAGCGAAGTGCTGCTGCCTTGGACGGCC
CGGTATTACGGTAATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAG
CCAAAAATACCGCATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATTG
TCGCGGTCGACGGGTATCTGGCAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAAAAACCGGCACGGATGAACGC
AGCTACAATCTGAAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGCAATGACTCCGACCTCGCCAA
AGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTA
CAGATGACCAAGACAAGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTTGGCGGCAGAGGCGCGTATGCCTTGGAT
TTAAGCAAAATCAACGGAAATTATCCGGCCGCCGCCCCCCTGTTTGATGTCAAAGATGGCGATAATAACGGCAAAAATCG
CGTGAAAGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCG
CCTCCGGTTATGCGGCTAAAGACATTAACAGCAACGACAATAAAACCGCGCTGTATGTGTATGATTTGGAAAACGGCAGT
GGTAGTCTGATTAAAAAAATCGAAGCACCCAGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGA
CGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGGAATATGTACCGCTTTGATTTGAGCAATTCCGATCCTAGTA
AATGGTCTGTAAGCACTATTTTCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGC
GTGGTCATCTTCGGCACGGGCAGCGATTTGAGTGAAGAGGATGTAGTCGGTACGAATCCACAATATATTTACGGTATCTT
TGACGACGATAAGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGTTGCTCGAGCAAGTGCTTAGCGAGG
AAAATAAAACATTATTCCTGAACAAGAGATCCGACGGATCGAACGGCAAAGGGTGGGTAGTGAGATTGAGGGAAGGAGAA
CGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTGACCATCCGGAAATATACGGATACGGACAAATGTGG
CGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGG
AAGCCAATAAGGATGTCGCACAATATTCCGGCCATAAGACAGCCGGCGGCAAGTCCGTCCCCATAGGCTGCATGTGGAAA
AACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGA
CGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACC
GGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGT
ATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterProScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(539-861)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

70.51

100

0.71