Detailed information NTG0789435

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: PUW46_RS12800
• Genome accession: NZ_CP118044
• Coordinates: 2597148..2598035 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain VSI56
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2592148..2603035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW46_RS12770 (PUW46_12770)	-	2592166..2592258 (+)	93	WP_010956583.1	hypothetical protein	-
PUW46_RS12775 (PUW46_12775)	-	2592366..2592863 (-)	498	WP_001065269.1	glutathione peroxidase	-
PUW46_RS12780 (PUW46_12780)	-	2592873..2593133 (-)	261	WP_001789910.1	hypothetical protein	-
PUW46_RS12785 (PUW46_12785)	-	2593515..2593628 (-)	114	Protein_2473	hypothetical protein	-
PUW46_RS12790 (PUW46_12790)	-	2594287..2596287 (-)	2001	WP_000776739.1	ABC transporter permease	-
PUW46_RS12795 (PUW46_12795)	-	2596284..2597039 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
PUW46_RS12800 (PUW46_12800)	braS	2597148..2598035 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
PUW46_RS12805 (PUW46_12805)	braR	2598046..2598711 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
PUW46_RS12810 (PUW46_12810)	-	2598737..2598937 (-)	201	WP_000604727.1	hypothetical protein	-
PUW46_RS12815 (PUW46_12815)	-	2599135..2600559 (+)	1425	WP_000953762.1	alkaline phosphatase	-
PUW46_RS12820 (PUW46_12820)	-	2600629..2600739 (+)	111	WP_001791296.1	hypothetical protein	-
PUW46_RS12825 (PUW46_12825)	-	2600842..2601297 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
PUW46_RS12830 (PUW46_12830)	-	2601542..2602303 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=789435 PUW46_RS12800 WP_000143420.1 2597148..2598035(-) (braS) [Staphylococcus aureus strain VSI56]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=789435 PUW46_RS12800 WP_000143420.1 2597148..2598035(-) (braS) [Staphylococcus aureus strain VSI56]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993