Detailed information NTG0789363

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: PUW57_RS02755
• Genome accession: NZ_CP118043
• Coordinates: 483064..484137 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain VSI63
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 478064..489137

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW57_RS02725 (PUW57_02725)	-	478957..480021 (+)	1065	WP_000021304.1	MmcQ/YjbR family DNA-binding protein	-
PUW57_RS02730 (PUW57_02730)	asnA	480135..481127 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
PUW57_RS02735 (PUW57_02735)	-	481172..481621 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
PUW57_RS02740 (PUW57_02740)	rsmD	481751..482290 (+)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
PUW57_RS02745 (PUW57_02745)	-	482302..482592 (+)	291	WP_000384889.1	hypothetical protein	-
PUW57_RS02750 (PUW57_02750)	coaD	482589..483074 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
PUW57_RS02755 (PUW57_02755)	sepM	483064..484137 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
PUW57_RS02760 (PUW57_02760)	-	484212..485544 (+)	1333	Protein_458	metallophosphoesterase	-
PUW57_RS02765 (PUW57_02765)	-	485613..486191 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
PUW57_RS02770 (PUW57_02770)	rlmN	486242..487348 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
PUW57_RS02775 (PUW57_02775)	-	487348..487863 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=789363 PUW57_RS02755 WP_000796095.1 483064..484137(+) (sepM) [Streptococcus agalactiae strain VSI63]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=789363 PUW57_RS02755 WP_000796095.1 483064..484137(+) (sepM) [Streptococcus agalactiae strain VSI63]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658