Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PUN35_RS08540 Genome accession   NZ_CP117986
Coordinates   1543251..1543907 (-) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus sp. N3378-2at     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1538251..1548907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUN35_RS08515 spxH 1538461..1539360 (+) 900 WP_003245184.1 protease adaptor protein SpxH -
  PUN35_RS08520 - 1539675..1539842 (+) 168 WP_003244944.1 hypothetical protein -
  PUN35_RS08525 pepF 1539880..1541709 (-) 1830 WP_173401378.1 oligoendopeptidase F -
  PUN35_RS08530 coiA 1541939..1543060 (-) 1122 WP_235091746.1 competence protein CoiA Machinery gene
  PUN35_RS08535 - 1543134..1543256 (+) 123 WP_003245684.1 hypothetical protein -
  PUN35_RS08540 mecA 1543251..1543907 (-) 657 WP_014479448.1 adaptor protein MecA Regulator
  PUN35_RS08545 - 1543874..1544014 (-) 141 WP_119122854.1 hypothetical protein -
  PUN35_RS08550 - 1544184..1544840 (+) 657 WP_014479447.1 TerC family protein -
  PUN35_RS08555 spx 1544883..1545278 (-) 396 WP_014476435.1 transcriptional regulator Spx -
  PUN35_RS08560 - 1545459..1546037 (-) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  PUN35_RS08565 - 1546201..1547418 (-) 1218 WP_072592593.1 MFS transporter -
  PUN35_RS08570 oppF 1547526..1548443 (-) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=788896 PUN35_RS08540 WP_014479448.1 1543251..1543907(-) (mecA) [Bacillus sp. N3378-2at]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=788896 PUN35_RS08540 WP_014479448.1 1543251..1543907(-) (mecA) [Bacillus sp. N3378-2at]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995