Detailed information NTG0788830

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PT798_RS11240
• Genome accession: NZ_CP117979
• Coordinates: 2313028..2314071 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain B-41012
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2308028..2319071

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PT798_RS11210	-	2308450..2309706 (-)	1257	WP_001789555.1	aminopeptidase	-
PT798_RS11215	-	2309709..2309909 (-)	201	WP_000180460.1	DUF1128 family protein	-
PT798_RS11220	-	2310056..2310520 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
PT798_RS11225	-	2310527..2310802 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
PT798_RS11230	-	2311080..2312297 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
PT798_RS11235	vraR	2312409..2313038 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
PT798_RS11240	vraS	2313028..2314071 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
PT798_RS11245	liaF	2314068..2314769 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
PT798_RS11250	-	2314784..2315170 (-)	387	WP_001110179.1	hypothetical protein	-
PT798_RS11255	map	2315387..2316145 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
PT798_RS11260	-	2316557..2317543 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
PT798_RS11265	-	2317974..2318387 (-)	414	WP_001670387.1	hypothetical protein	-
PT798_RS11270	-	2318416..2318526 (-)	111	WP_031775032.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=788830 PT798_RS11240 WP_001017131.1 2313028..2314071(-) (vraS) [Staphylococcus aureus strain B-41012]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=788830 PT798_RS11240 WP_001017131.1 2313028..2314071(-) (vraS) [Staphylococcus aureus strain B-41012]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1