Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q6378_RS06475 Genome accession   NZ_CP130889
Coordinates   1234135..1237275 (+) Length   1046 a.a.
NCBI ID   WP_304674276.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain NJ209649     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1229135..1242275
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q6378_RS06455 (Q6378_06455) - 1229681..1230130 (-) 450 WP_003688065.1 CopD family copper resistance protein -
  Q6378_RS06460 (Q6378_06460) waaA 1230171..1231442 (-) 1272 WP_010360974.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  Q6378_RS06465 (Q6378_06465) gnd 1231505..1232953 (-) 1449 WP_003688061.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  Q6378_RS06470 (Q6378_06470) - 1233033..1233296 (-) 264 WP_017147189.1 hypothetical protein -
  Q6378_RS06475 (Q6378_06475) pilC 1234135..1237275 (+) 3141 WP_304674276.1 PilC family type IV pilus tip adhesin Machinery gene
  Q6378_RS06480 (Q6378_06480) - 1237927..1238211 (+) 285 WP_003692093.1 GIY-YIG nuclease family protein -
  Q6378_RS06485 (Q6378_06485) yccS 1238691..1240841 (-) 2151 WP_003697785.1 YccS family putative transporter -
  Q6378_RS06490 (Q6378_06490) pilU 1240958..1242184 (-) 1227 WP_003697786.1 PilT/PilU family type 4a pilus ATPase Machinery gene

Sequence

Protein


Download         Length: 1046 a.a.        Molecular weight: 114925.22 Da        Isoelectric Point: 9.8873

>NTDB_id=787950 Q6378_RS06475 WP_304674276.1 1234135..1237275(+) (pilC) [Neisseria gonorrhoeae strain NJ209649]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGQAQARDYAIIMNERNQPDVRWDGQYQKSQLREKDRERKFIYNKDRQGGGS
VFFDNTDELVSQQSGTAVFGTATYLPPYGKVSGFDADGLKKRGNAVNWIRTTRPGLAGYVYTGVICRDAKQCPELIYETK
FSFDGIGLAKGGNRKLDRHPDPSRDNSPIYKLKDYPWLGVSFNLGGENTAKDGRSSSRWISSFSEDNNNQTIVFTTRGHP
ISLGDWQRESTAMAYYLNAKLHLLDKKKIENIAPGKTVDLGTLRPRVEAKVRRGWSLLNFWSKWDIKDNGQIPVKLGLPE
VKAGRCTNKPNPNPKSKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPGRHSLAALDT
QNIKSREPNFNSRQTVIRLPGGVYKISSGKNGGRVAGFNGDDGKNDTFGIYKDRLVTPDADEWAKVLLPWTVRYYGNDDI
FKTFNQPNSKTQNGKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATSANDGMVHLFKRNGTDQRGYELKLSY
IPGTMERKDIEGNDSDLAKELRAFAEKGYVGDRYGVDGGFVLRRITDDQDRQKHFFMFGAMGLGGRGAYALDLTKIDSNN
LTGVSMFDVQNDKNNNNNDSNRVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKDIVSSDNTTALYVYDLGNGGGSLIKKI
EAPGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSDNDPNKWSVRTIFEGGKPITSAPAVSRLADKRVVIFGTG
SDLSEEDVVDTKEQYIYGIFDDDKGTVKVTVQNGTGGGLLKQTLTKESKTLFLSNNKASGGSADKGWVVKLMDGERVTVK
PTVVLRTAFVTIRKYTDTDKCGAQTAILGINTADGGALTPRSARPIVPEANKDVAQYSGHKTAGGKSVPIGCMWKNSKTV
CPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGIKRLS
WREVFF

Nucleotide


Download         Length: 3141 bp        

>NTDB_id=787950 Q6378_RS06475 WP_304674276.1 1234135..1237275(+) (pilC) [Neisseria gonorrhoeae strain NJ209649]
ATGAATAAAACTTTGAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGCAGGCGCAAGCCCGTGACTACGCTATTATCATGAACGAACGAAATCAGCCGGATGTAAGGTGGGATGGGC
AATATCAAAAATCACAATTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAGACAGACAGGGTGGAGGCTCT
GTCTTTTTCGACAATACCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCC
CTACGGCAAGGTTTCCGGTTTTGATGCCGACGGGCTGAAAAAGCGCGGCAATGCCGTCAATTGGATTCGTACCACCCGGC
CCGGGCTGGCAGGCTACGTCTACACCGGCGTCATATGCAGAGACGCAAAGCAATGCCCCGAACTTATCTATGAGACCAAA
TTTTCCTTCGACGGCATCGGTTTGGCAAAAGGGGGAAACCGAAAGCTGGATAGGCACCCGGACCCAAGCCGCGACAATTC
GCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGGGCGGCGAGAATACCGCCAAAGATGGCA
GATCATCCAGCAGATGGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTTTACGACACGAGGCCACCCT
ATTTCCCTTGGCGACTGGCAGCGCGAAAGTACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAA
AAAGATTGAAAATATCGCGCCAGGCAAAACAGTGGATTTGGGCACCTTGAGACCGCGCGTCGAGGCAAAGGTAAGGCGGG
GGTGGAGTCTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAA
GTCAAAGCCGGGCGCTGCACCAACAAACCGAACCCCAATCCCAAATCCAAAGCCCCTTCGCCGGCACTGACCGCCCCCGC
GCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGGCAGCTCGAGCA
GCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGCCGGCATTCCCTCGCCGCTTTGGATACG
CAGAACATCAAAAGCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCCGATTGCCGGGCGGCGTGTACAAGATCAG
CTCGGGCAAGAACGGCGGCCGGGTCGCGGGTTTTAATGGCGATGACGGCAAAAACGACACTTTCGGCATCTACAAGGACA
GGCTCGTCACACCTGATGCCGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTACGGTAATGACGATATA
TTTAAAACATTCAACCAACCAAACAGCAAAACACAAAACGGCAAAAAACAATACAGCCAAAAATACCGCATCCGCACAAA
AGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGCGGTCGGCGGGTATCTGGCAA
CTTCTGCCAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACGAGGCTACGAACTGAAGCTCAGCTAC
ATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGCAATGACTCCGACCTCGCCAAAGAGCTGCGCGCCTTTGCCGAAAA
AGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAGGACAGGCAAAAAC
ATTTCTTTATGTTTGGTGCGATGGGCCTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAATCGACAGCAACAAC
CTGACCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAACAATGACAGTAATCGCGTGAAATTAGGCTA
CACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAAG
ATATTGTCAGCAGCGATAATACAACCGCGCTGTATGTGTATGATTTGGGAAACGGCGGTGGTAGTCTGATTAAAAAAATC
GAAGCACCCGGCGGCAAAGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACAGTCGATATCGCCTA
TGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCGACAACGACCCGAACAAATGGTCTGTACGCACTATTT
TCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTCGTCATCTTCGGTACGGGC
AGCGATTTGAGTGAAGAGGATGTAGTCGATACGAAAGAACAATATATTTACGGTATCTTCGACGACGATAAGGGGACGGT
TAAGGTAACGGTACAAAACGGCACGGGAGGCGGGCTGCTCAAGCAAACGCTTACGAAGGAAAGTAAAACCTTGTTCCTGA
GCAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTGATGGACGGAGAACGCGTTACCGTCAAA
CCGACCGTGGTATTGCGTACCGCCTTCGTGACCATCCGGAAATATACGGATACGGACAAATGTGGCGCGCAAACCGCCAT
TTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGAAGCCAATAAGGATG
TCGCACAATATTCCGGCCATAAGACAGCCGGCGGCAAGTCCGTCCCCATAGGCTGCATGTGGAAAAACAGCAAAACCGTC
TGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGTTACCTGGACGAAAAGAAAACAGACGATTTCCCCGTCAC
GGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAA
AAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGC
TGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterProScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(517-857)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

74.405

100

0.748