Detailed information NTG0787436

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: OG742_RS19600
• Genome accession: NZ_CP130727
• Coordinates: 4426610..4429138 (-)
• Length: 842 a.a.
• NCBI ID: WP_266456974.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00828
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4421610..4434138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG742_RS19585 (OG742_19550)	-	4421726..4422331 (-)	606	WP_405907305.1	M23 family metallopeptidase	-
OG742_RS19590 (OG742_19555)	-	4422884..4423258 (+)	375	WP_266456968.1	trypco2 family protein	-
OG742_RS19595 (OG742_19560)	-	4423255..4426536 (+)	3282	WP_405907306.1	NACHT domain-containing protein	-
OG742_RS19600 (OG742_19565)	clpC	4426610..4429138 (-)	2529	WP_266456974.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
OG742_RS19605 (OG742_19570)	-	4429569..4430267 (+)	699	WP_405907307.1	SCO3374 family protein	-
OG742_RS19610 (OG742_19575)	-	4430246..4430581 (-)	336	WP_266456980.1	Lsr2 family protein	-
OG742_RS19615 (OG742_19580)	-	4430810..4431379 (-)	570	WP_266456983.1	amino-acid N-acetyltransferase	-
OG742_RS19620 (OG742_19585)	-	4431389..4431781 (-)	393	WP_266456986.1	BlaI/MecI/CopY family transcriptional regulator	-
OG742_RS19625 (OG742_19590)	-	4431918..4432097 (-)	180	WP_266456989.1	hypothetical protein	-
OG742_RS19630 (OG742_19595)	-	4432111..4432710 (-)	600	WP_405911093.1	hypothetical protein	-
OG742_RS19635 (OG742_19600)	-	4433044..4433841 (-)	798	WP_266456992.1	type III pantothenate kinase	-

Sequence

Protein

• Length: 842 a.a.
• Molecular weight: 93070.37 Da
• Isoelectric Point: 5.9363

>NTDB_id=787436 OG742_RS19600 WP_266456974.1 4426610..4429138(-) (clpC) [Streptomyces sp. NBC_00828]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKETAGASGGPAEG
TPSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLK
DKHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGAT
TLDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLI
DEAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGEL
IAEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELS
KTLAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILE
DGRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAVGDVKSNYDRMKAKVNEELKQHFRPEFLNRVDDTVVFHQL
TEEDIIQIVDLMVAKVDERLKDRDMGLELSPTAKSLLAKKGYDPVMGARPLRRTIQREIEDLLSEKILFGELRPGQIVVV
DTEGEGDAKKFTFRGEEKSALPDVPPIEQAAGGAGPNLSKEA

Nucleotide

• Length: 2529 bp

>NTDB_id=787436 OG742_RS19600 WP_266456974.1 4426610..4429138(-) (clpC) [Streptomyces sp. NBC_00828]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGGCAGGGTCAGCAGGCCCCGTCCGGGCACATCCCCTTC
ACCCCCCGTGCCAAGAAGGTCCTGGAGCTCTCGCTCCGCGAGGCCCTTCAGCTGGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGTGAGGGCGAGGGCGTCGCCGCCCAGGTCCTGGTCAAGCTGGGCGCAGACCTCAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGCTACCAGGGCAAGGAGACCGCCGGCGCCAGTGGCGGTCCTGCCGAGGGC
ACTCCCTCGACGTCCCTGGTCCTCGACCAGTTCGGCCGGAACCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGT
CATCGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGCACCAAGAACAACCCGGTCCTGATCGGTG
AGCCCGGCGTCGGCAAGACCGCCGTCGTCGAGGGTCTCGCCCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAG
GACAAGCACCTCTACACCCTGGACCTCGGCGCGCTGGTCGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAA
GAAGGTGCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTCGGTGCGGGTG
CCGCCGAGGGCGCCATCGACGCGGCTTCGATCCTGAAGCCGATGCTGGCCCGTGGCGAGCTGCAGACCATCGGTGCGACG
ACTCTGGACGAGTACCGCAAGCACCTCGAGAAGGACGCGGCCCTCGAGCGCCGCTTCCAGCCGATCCAGGTGGCGGAGCC
TTCCCTCCCCCACACGATCGAGATCCTCAAGGGACTGCGGGACCGCTACGAGGCCCACCACCGCGTCTCCATCACGGACG
AGGCCCTGGTGCAGGCCGCGACGCTCGCGGACCGCTACATCTCCGACCGGTTCCTCCCCGACAAGGCGATCGACCTGATC
GACGAGGCGGGCTCCCGGATGCGTATCCGCCGGATGACCGCTCCGCCGGACCTCCGCGAGTTCGACGAGAAGATCGCGGG
CGTGCGCCGCGACAAGGAGTCCGCGATCGATTCGCAGGACTTCGAGAAGGCCGCCTCCCTCCGCGACAAGGAGAAGCAGC
TCCTGGCCGCCAAGGCCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGCGAGCTG
ATCGCCGAGGTCCTCGCGACCGCCACCGGCATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCTCGCGTCTGCTGCGCAT
GGAGGACGAGCTCCACAAGCGGGTCATCGGCCAGAAGGACGCCATCAAGGCGCTCTCGCAGGCGATCCGTCGTACGCGAG
CGGGTCTGAAGGACCCGAAGCGTCCCGGTGGTTCGTTCATCTTCGCGGGCCCGTCGGGTGTCGGTAAGACGGAACTCTCC
AAGACCCTGGCCGAGTTCCTCTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACAC
GGTGTCGCGTCTCTTCGGTTCGCCCCCCGGTTACGTGGGCTACGAAGAGGGTGGCCAGCTGACGGAGAAGGTGCGTCGGA
AGCCGTTCTCGGTGGTTCTCTTCGACGAGGTCGAAAAGGCCCACCCGGACATCTTCAACTCGCTTCTCCAGATCCTGGAG
GATGGTCGCCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGCAC
CCGGGACATCTCCAAGGGCTTCAACCTCGGCTTCGCCGCCGTGGGTGACGTCAAGTCCAACTACGACCGGATGAAGGCCA
AGGTCAACGAGGAGCTGAAGCAGCACTTCCGCCCCGAGTTCCTGAACCGTGTCGACGACACGGTGGTCTTCCACCAGCTC
ACCGAGGAAGACATCATCCAGATCGTCGACCTCATGGTCGCCAAGGTGGACGAGCGGCTGAAGGACCGGGACATGGGCCT
CGAGCTCAGCCCGACCGCCAAGTCGCTCCTCGCGAAGAAGGGTTACGACCCCGTCATGGGCGCCCGGCCGCTGCGCCGGA
CGATCCAGCGCGAGATCGAGGACCTGCTCTCCGAGAAGATCCTCTTCGGCGAGCTGCGTCCCGGCCAGATCGTGGTCGTC
GACACGGAGGGCGAGGGTGACGCGAAGAAGTTCACCTTCCGGGGCGAGGAGAAGTCCGCGCTCCCCGACGTCCCGCCGAT
CGAGCAGGCGGCCGGCGGCGCCGGCCCGAACCTGAGCAAGGAGGCGTAG

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (720-800)

• AAA lid domain (AAA_lid_9) (350-450)

• AAA domain (Cdc48 subfamily) (AAA_2) (542-713)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (210-330)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	61.519	95.368	0.587
clpC	Streptococcus mutans UA159	45.06	98.575	0.444
clpC	Streptococcus thermophilus LMD-9	43.929	99.762	0.438
clpC	Streptococcus thermophilus LMG 18311	43.757	99.881	0.437
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	44.212	96.437	0.426
clpC	Streptococcus pneumoniae Rx1	44.125	95.012	0.419
clpC	Streptococcus pneumoniae D39	44.125	95.012	0.419
clpC	Streptococcus pneumoniae TIGR4	43.875	95.012	0.417
clpE	Streptococcus mutans UA159	53.834	74.347	0.4
clpC	Lactococcus lactis subsp. cremoris KW2	50.301	78.86	0.397
clpE	Streptococcus pneumoniae TIGR4	52.648	73.99	0.39
clpE	Streptococcus pneumoniae Rx1	52.488	73.99	0.388
clpE	Streptococcus pneumoniae D39	52.488	73.99	0.388
clpE	Streptococcus pneumoniae R6	52.488	73.99	0.388