Detailed information NTG0786253

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: Q4V64_RS13505
• Genome accession: NZ_CP130630
• Coordinates: 3099652..3100713 (+)
• Length: 353 a.a.
• NCBI ID: WP_124442890.1
• Uniprot ID: -
• Organism: Streptomyces sp. NL15-2K
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3094652..3105713

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q4V64_RS13475 (Q4V64_13470)	-	3094758..3095441 (-)	684	WP_124442896.1	response regulator transcription factor	-
Q4V64_RS13480 (Q4V64_13475)	-	3095438..3096667 (-)	1230	WP_124442895.1	histidine kinase	-
Q4V64_RS13485 (Q4V64_13480)	-	3096775..3097059 (-)	285	WP_124442894.1	hypothetical protein	-
Q4V64_RS13490 (Q4V64_13485)	-	3097099..3097893 (-)	795	WP_124442893.1	PspA/IM30 family protein	-
Q4V64_RS13495 (Q4V64_13490)	-	3098145..3098774 (+)	630	WP_124442892.1	DUF3043 domain-containing protein	-
Q4V64_RS13500 (Q4V64_13495)	-	3098858..3099595 (+)	738	WP_124442891.1	methyltransferase domain-containing protein	-
Q4V64_RS13505 (Q4V64_13500)	htrA	3099652..3100713 (+)	1062	WP_124442890.1	trypsin-like peptidase domain-containing protein	Regulator
Q4V64_RS13510 (Q4V64_13505)	-	3100768..3100983 (-)	216	WP_124442889.1	hypothetical protein	-
Q4V64_RS13515 (Q4V64_13510)	-	3101220..3102422 (+)	1203	WP_124442888.1	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	-
Q4V64_RS13520 (Q4V64_13515)	-	3102411..3103109 (-)	699	WP_124442887.1	class I SAM-dependent methyltransferase	-
Q4V64_RS13525 (Q4V64_13520)	cobT	3103270..3104379 (+)	1110	WP_124442886.1	nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	-
Q4V64_RS13530 (Q4V64_13525)	-	3104422..3105186 (-)	765	WP_124442885.1	hypothetical protein	-

Sequence

Protein

• Length: 353 a.a.
• Molecular weight: 35823.84 Da
• Isoelectric Point: 4.3341

>NTDB_id=786253 Q4V64_RS13505 WP_124442890.1 3099652..3100713(+) (htrA) [Streptomyces sp. NL15-2K]
MDASRTRALRLVAVLACSVALLSGCTGSDSSGERENPTTQAAVPAVDSDLQSDYQKVIRDVLPSVVQIQARSDLGSGVVY
DGRGHIVTNAHVVGDEKTFQVTTANSEDALDATLVYSYPEQDLAVIKLDRVPGGLRAASFGDSSKVEVGQIVLAMGSPLG
LSSSVTQGIVSATGRTVTETQADGGTGATIADMVQTSAAINPGNSGGALVNLDGQVIGIPTLAATDPGLGDSAAPGIGFA
IPASTVRTIADQIVKQGRVTDSGRAGLGITGRTVVDDDYRAAGVAVVEVTGGGAADKAGIEAGDVITKLGDTDITTITSL
TEALAARRPGDRTSVTFTRNGDERTVEVTLGER

Nucleotide

• Length: 1062 bp

>NTDB_id=786253 Q4V64_RS13505 WP_124442890.1 3099652..3100713(+) (htrA) [Streptomyces sp. NL15-2K]
ATGGATGCCTCTCGTACCCGTGCCCTGCGGCTGGTCGCCGTGCTCGCGTGTTCCGTCGCGCTCCTGTCCGGATGCACCGG
ATCGGATTCCTCCGGCGAGCGGGAGAACCCGACCACACAGGCCGCCGTTCCCGCCGTGGACAGCGATCTGCAGAGCGACT
ACCAGAAGGTGATCAGGGACGTTCTGCCGTCGGTCGTGCAGATCCAGGCCAGGAGCGATCTCGGGTCGGGCGTCGTGTAC
GACGGCCGGGGGCACATCGTCACCAACGCCCATGTCGTCGGGGACGAGAAGACCTTCCAGGTGACGACCGCCAACAGCGA
GGACGCCCTCGACGCGACACTCGTCTACTCGTACCCCGAGCAGGATCTCGCCGTCATCAAGCTGGACCGGGTTCCGGGCG
GGCTGAGGGCCGCGTCCTTCGGGGACTCCTCGAAGGTGGAGGTGGGGCAGATCGTCCTCGCCATGGGCTCGCCGCTCGGG
CTGTCGTCCAGCGTGACGCAGGGGATCGTGTCGGCGACCGGGCGGACCGTCACCGAGACCCAGGCGGACGGCGGTACGGG
CGCGACCATCGCCGACATGGTGCAGACCTCGGCCGCCATCAACCCCGGCAACAGCGGGGGTGCGCTGGTGAACCTCGACG
GGCAGGTCATCGGCATCCCGACGCTCGCCGCCACCGACCCCGGCCTCGGGGACAGCGCGGCGCCCGGCATCGGGTTCGCG
ATCCCGGCGTCGACGGTGAGGACCATCGCCGACCAGATCGTCAAGCAGGGCAGGGTCACCGACTCGGGACGGGCCGGGCT
CGGCATCACCGGTCGTACGGTCGTCGACGACGACTACCGGGCCGCCGGGGTGGCCGTGGTCGAGGTGACGGGCGGTGGGG
CCGCCGACAAGGCCGGCATCGAGGCCGGGGACGTCATCACCAAGTTGGGTGACACGGACATCACCACCATCACCTCGCTG
ACCGAGGCGCTGGCTGCCCGGAGGCCGGGCGACAGGACATCGGTCACCTTCACGCGCAACGGCGATGAGAGAACCGTGGA
GGTGACCCTGGGTGAGCGGTGA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (268-350)

• Peptidase family M50 (Peptidase_M50) (226-350)

• Trypsin-like peptidase domain (Trypsin_2) (75-219)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	33.077	100	0.365