Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   IL310_RS02685 Genome accession   NZ_CP117409
Coordinates   128100..129128 (+) Length   342 a.a.
NCBI ID   WP_003132657.1    Uniprot ID   S6FVM6
Organism   Lactococcus lactis strain LB7     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 123100..134128
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IL310_RS02660 (IL310_02665) - 123648..124142 (-) 495 WP_201248990.1 RNA polymerase sigma factor -
  IL310_RS02665 (IL310_02670) lmrP 124330..125556 (+) 1227 WP_012898648.1 multidrug efflux MFS transporter LmrP -
  IL310_RS02670 (IL310_02675) - 125639..126859 (+) 1221 WP_201248989.1 MFS transporter -
  IL310_RS02675 (IL310_02680) rsmD 127029..127568 (+) 540 WP_050558566.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  IL310_RS02680 (IL310_02685) coaD 127616..128113 (+) 498 WP_010906348.1 pantetheine-phosphate adenylyltransferase -
  IL310_RS02685 (IL310_02690) sepM 128100..129128 (+) 1029 WP_003132657.1 SepM family pheromone-processing serine protease Regulator
  IL310_RS02690 (IL310_02695) - 129249..130106 (+) 858 WP_021723356.1 transcription regulator -
  IL310_RS02695 (IL310_02700) - 130209..132332 (+) 2124 WP_168784963.1 radical SAM protein -
  IL310_RS02700 (IL310_02705) - 132325..133152 (+) 828 WP_010906344.1 radical SAM protein -
  IL310_RS02705 (IL310_02710) - 133149..133358 (+) 210 WP_003132661.1 hypothetical protein -
  IL310_RS02710 (IL310_02715) - 133345..133842 (+) 498 WP_021214977.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37349.96 Da        Isoelectric Point: 9.9183

>NTDB_id=784613 IL310_RS02685 WP_003132657.1 128100..129128(+) (sepM) [Lactococcus lactis strain LB7]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=784613 IL310_RS02685 WP_003132657.1 128100..129128(+) (sepM) [Lactococcus lactis strain LB7]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTTCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGCGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FVM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.491