Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   M2038_RS03540 Genome accession   NZ_AP025693
Coordinates   737388..738062 (+) Length   224 a.a.
NCBI ID   WP_001166505.1    Uniprot ID   Q2FIY0
Organism   Staphylococcus aureus strain JICS127     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 732388..743062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2038_RS03515 (JICS127ACC_0674) - 732603..733670 (+) 1068 WP_000980137.1 membrane protein -
  M2038_RS03520 (JICS127ACC_0675) - 733821..734864 (+) 1044 WP_001030771.1 alpha/beta hydrolase -
  M2038_RS03525 (JICS127ACC_0676) - 735193..735621 (+) 429 WP_000198504.1 hypothetical protein -
  M2038_RS03530 (JICS127ACC_0677) - 735830..736336 (-) 507 WP_000940134.1 GNAT family N-acetyltransferase -
  M2038_RS03535 (JICS127ACC_0678) graX 736449..737372 (+) 924 WP_000802946.1 auxiliary protein GraX/ApsX -
  M2038_RS03540 (JICS127ACC_0679) braR 737388..738062 (+) 675 WP_001166505.1 response regulator transcription factor GraR/ApsR Regulator
  M2038_RS03545 (JICS127ACC_0680) graS 738055..739095 (+) 1041 WP_001061252.1 histidine kinase GraS/ApsS -
  M2038_RS03550 (JICS127ACC_0681) vraF 739239..740000 (+) 762 WP_000985996.1 ABC transporter ATP-binding protein VraF -
  M2038_RS03555 (JICS127ACC_0682) vraG 739990..741879 (+) 1890 WP_000143623.1 ABC transporter permease VraG -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26078.92 Da        Isoelectric Point: 4.3968

>NTDB_id=78418 M2038_RS03540 WP_001166505.1 737388..738062(+) (braR) [Staphylococcus aureus strain JICS127]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDQTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=78418 M2038_RS03540 WP_001166505.1 737388..738062(+) (braR) [Staphylococcus aureus strain JICS127]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAACCGTTCTATACCAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGATCAGACGATTTTCCTGTCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATTAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2FIY0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.909

98.214

0.402