Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   MGCS35957_RS07720 Genome accession   NZ_CP117288
Coordinates   1544467..1546758 (+) Length   763 a.a.
NCBI ID   WP_084916336.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1539467..1551758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS35957_RS07695 (MGCS35957_03160) feoB 1539557..1541716 (-) 2160 WP_015017220.1 ferrous iron transport protein B -
  MGCS35957_RS07700 (MGCS35957_03162) - 1541713..1542192 (-) 480 WP_003056958.1 ferrous iron transport protein A -
  MGCS35957_RS07705 (MGCS35957_03164) - 1542392..1543126 (-) 735 WP_084916338.1 amino acid ABC transporter ATP-binding protein -
  MGCS35957_RS07710 (MGCS35957_03166) - 1543126..1543812 (-) 687 WP_003051835.1 amino acid ABC transporter permease -
  MGCS35957_RS07715 (MGCS35957_03168) - 1543940..1544170 (-) 231 WP_003051836.1 DUF1797 family protein -
  MGCS35957_RS07720 (MGCS35957_03170) clpE 1544467..1546758 (+) 2292 WP_084916336.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  MGCS35957_RS07725 (MGCS35957_03172) - 1546876..1547331 (+) 456 WP_022554961.1 NUDIX hydrolase -
  MGCS35957_RS07730 (MGCS35957_03174) - 1547381..1547683 (+) 303 WP_065957262.1 DUF1827 family protein -
  MGCS35957_RS07735 (MGCS35957_03178) ileS 1548086..1550887 (-) 2802 WP_084916335.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84940.27 Da        Isoelectric Point: 5.4239

>NTDB_id=783394 MGCS35957_RS07720 WP_084916336.1 1544467..1546758(+) (clpE) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957]
MLCQNCNLNESTIHLYTNVNGKKKQVDLCQNCYQIMKTDPTNPILGGLNGGQRAQERSSTPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRHGGHFNGQRPTQPQTPNQQAKGLLEEFGINVTDIARHGDIDPVIGRDDEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIVDGTVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERIQKLMEEIRQRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
IAKYKEMQAQKVDEQDIPIITEKTIEAIIEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKDNLLHIVDLMLEDVNKRLSYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKDLRAIMTSNSNIMIKAAKKDETVTAKQDKTDEN

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=783394 MGCS35957_RS07720 WP_084916336.1 1544467..1546758(+) (clpE) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957]
ATGCTTTGTCAAAATTGTAATTTAAACGAATCAACCATTCACCTCTACACGAATGTTAATGGAAAAAAAAAACAAGTTGA
CCTTTGTCAAAACTGTTATCAAATCATGAAGACTGACCCTACTAATCCTATTTTAGGTGGTCTAAATGGAGGTCAAAGAG
CCCAAGAACGCTCATCCACCCCCTTCTTTGATGACTTTTTTGGGGACTTAAATAATTTTAGAGCCTTCGGTAACCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGTGGGGGACGCCATGGTGGTCATTTCAATGGACAACGTCCCAC
TCAGCCACAAACACCAAATCAGCAAGCAAAAGGCTTGCTAGAAGAATTTGGCATTAATGTGACCGATATTGCAAGACATG
GTGATATTGACCCTGTCATCGGTCGAGATGACGAGATTACACGTGTCATCGAAATCCTTAACCGTCGGACTAAAAATAAC
CCTGTGCTTATTGGGGAACCAGGAGTTGGTAAAACAGCTGTTGTAGAAGGTCTAGCCCAAAAAATTGTAGATGGCACAGT
ACCTCACAAATTGCAAGGTAAGCAAGTGATCCGTCTAGATGTGGTTAGTCTTGTTCAAGGCACAGGTATCCGTGGTCAAT
TCGAAGAACGCATACAAAAATTAATGGAAGAAATTCGTCAACGCAAAGATGTGATTCTCTTTATTGATGAAATTCATGAA
ATTGTAGGTGCTGGTTCTGCTGGAGATGGCAATATGGATGCTGGCAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACCTTAAATGAATACCGTATTATTGAAAAAGATGCTGCCTTGGAGCGGCGGATGCAGCCGG
TGAAAGTTGACGAACCTTCTGTAGAAGAAACCATTACCATCTTAAAAGGTATCCAACCCAAATATGAAGACTATCATCAT
GTCAAATATAGCCCAGCAGCTATCGAGGCTGCTGCACACTTATCCAATCGCTACATCCAAGACCGATTCCTCCCTGATAA
GGCCATTGACCTTCTGGACGAAGCTGGTTCAAAAATGAATTTAACTCTTAATTTTGTTGACCCTAAAGAGATTGACAAAC
GTCTGATTGAAGCAGAAAACCTCAAAGCTCAAGCAACTCGTGACGAAGATTACGAACGAGCAGCCTATTTCCGTGATCAA
ATTGCGAAATACAAGGAAATGCAAGCTCAAAAAGTCGACGAACAGGATATTCCTATCATTACTGAAAAAACCATTGAAGC
CATCATTGAACAAAAAACCAATATTCCAGTTGGCGACTTGAAAGAAAAAGAACAATCTCAACTCGTTAATTTGGCTAATG
ATTTGAAAGCTCACGTGATTGGCCAAGATGATGCCGTTGACAAAATTGCCAAGGCCATTCGCCGGAACCGTGTGGGATTG
GGAACTCCAAATCGTCCTATTGGTTCTTTCCTATTCGTTGGGCCAACAGGTGTTGGTAAAACAGAGTTGTCTAAGCAACT
AGCTATTGAACTCTTTGGCTCTGCTGACAATATGATTCGCTTTGATATGTCCGAATACATGGAAAAACATGCCGTTGCTA
AATTAGTCGGGGCTCCTCCTGGTTATGTGGGCTATGAAGAAGCTGGCCAGTTAACGGAACAAGTTCGCCGCAACCCATAT
TCACTTATTCTCTTAGATGAGGTGGAAAAGGCTCATCCTGACGTCATGCACATGTTTTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGGACAGTCAGCTTCAAGGATACTATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GCGAAGCTTCTGTTGGATTTGGTGCAGCTAGAGAAGGACGAACAAGCTCTGTCCTTGGTGAATTAAGTAACTTCTTCAGC
CCAGAGTTCATGAACCGTTTCGATGGTATTATTGAATTTAAGGCCTTGAGCAAAGATAACCTCTTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATAAGCGCTTAAGCTATAATGGGATTCACCTTGATGTGACACAAAAAGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGTGCTCGACCACTCCGTCGTACCATCCAAGATTATATCGAAGATGCGATTACG
GACTACTATTTGGAACACCCCACTGAAAAGGACTTGCGTGCCATAATGACAAGTAACAGTAATATCATGATTAAAGCTGC
CAAAAAAGATGAAACGGTAACAGCTAAACAAGATAAGACCGACGAGAACTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(656-730)

AAA domain (Cdc48 subfamily) (AAA_2)

(485-648)

ATPase family associated with various cellular activities (AAA) (AAA)

(162-281)

AAA lid domain (AAA_lid_9)

(300-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.185

99.083

0.844
  clpE Streptococcus pneumoniae Rx1

83.926

99.476

0.835
  clpE Streptococcus pneumoniae D39

83.926

99.476

0.835
  clpE Streptococcus pneumoniae R6

83.926

99.476

0.835
  clpE Streptococcus pneumoniae TIGR4

83.794

99.476

0.834
  clpC Lactococcus lactis subsp. cremoris KW2

76.423

96.723

0.739
  clpC Bacillus subtilis subsp. subtilis str. 168

51.138

86.37

0.442
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.462

85.19

0.396
  clpC Streptococcus pneumoniae TIGR4

47.84

81.913

0.392
  clpC Streptococcus pneumoniae Rx1

47.84

81.913

0.392
  clpC Streptococcus pneumoniae D39

47.84

81.913

0.392
  clpC Streptococcus mutans UA159

47.411

80.996

0.384
  clpC Streptococcus thermophilus LMD-9

46.474

81.782

0.38
  clpC Streptococcus thermophilus LMG 18311

46.154

81.782

0.377