Detailed information NTG0783256

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: Q3V79_RS10220
• Genome accession: NZ_CP130513
• Coordinates: 2059111..2059818 (+)
• Length: 235 a.a.
• NCBI ID: WP_000094093.1
• Uniprot ID: A0A1D4DWM6
• Organism: Staphylococcus aureus strain SA29-SX
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2054111..2064818

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V79_RS10170	-	2054875..2055138 (-)	264	WP_001205732.1	hypothetical protein	-
Q3V79_RS10175	-	2055147..2055407 (-)	261	WP_000291489.1	DUF1108 family protein	-
Q3V79_RS10180	-	2055500..2055661 (-)	162	WP_000066020.1	DUF1270 domain-containing protein	-
Q3V79_RS10185	-	2055658..2055969 (-)	312	WP_029720056.1	DUF771 domain-containing protein	-
Q3V79_RS10190	-	2056035..2056667 (+)	633	WP_000275058.1	hypothetical protein	-
Q3V79_RS10195	-	2056682..2056821 (-)	140	Protein_1973	hypothetical protein	-
Q3V79_RS10200	-	2056852..2057046 (-)	195	WP_000388066.1	hypothetical protein	-
Q3V79_RS10205	-	2057063..2057814 (-)	752	Protein_1975	phage antirepressor KilAC domain-containing protein	-
Q3V79_RS10210	-	2057868..2058407 (+)	540	WP_000351243.1	hypothetical protein	-
Q3V79_RS10215	-	2058431..2058691 (-)	261	WP_000435341.1	transcriptional regulator	-
Q3V79_RS10220	irvR	2059111..2059818 (+)	708	WP_000094093.1	XRE family transcriptional regulator	Regulator
Q3V79_RS10225	-	2059830..2059985 (+)	156	WP_001049399.1	hypothetical protein	-
Q3V79_RS10230	-	2059972..2060157 (+)	186	WP_001089804.1	hypothetical protein	-
Q3V79_RS10235	-	2060357..2060524 (+)	168	WP_000705238.1	hypothetical protein	-
Q3V79_RS10240	-	2060664..2061203 (+)	540	WP_000391618.1	type II toxin-antitoxin system PemK/MazF family toxin	-
Q3V79_RS10245	-	2061376..2062413 (+)	1038	WP_000857198.1	site-specific integrase	-
Q3V79_RS10250	-	2062871..2063050 (+)	180	WP_000669791.1	hypothetical protein	-
Q3V79_RS14345	-	2063074..2063382 (+)	309	WP_001792927.1	hypothetical protein	-
Q3V79_RS10255	-	2063361..2063621 (+)	261	WP_001791826.1	hypothetical protein	-
Q3V79_RS10260	scn	2063674..2064024 (-)	351	WP_000702262.1	complement inhibitor SCIN-A	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 26769.35 Da
• Isoelectric Point: 5.4082

>NTDB_id=783256 Q3V79_RS10220 WP_000094093.1 2059111..2059818(+) (irvR) [Staphylococcus aureus strain SA29-SX]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide

• Length: 708 bp

>NTDB_id=783256 Q3V79_RS10220 WP_000094093.1 2059111..2059818(+) (irvR) [Staphylococcus aureus strain SA29-SX]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (123-234)

• Helix-turn-helix (HTH_3) (8-61)

3D structure

• AlphaFold DB: A0A1D4DWM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	30.769	100	0.374