Detailed information NTG0782967

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PQQ26_RS09695
• Genome accession: NZ_CP117230
• Coordinates: 1967173..1968216 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ATCC 25923
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1962173..1973216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PQQ26_RS09665 (PQQ26_09665)	-	1962594..1963850 (-)	1257	WP_001793983.1	aminopeptidase	-
PQQ26_RS09670 (PQQ26_09670)	-	1963853..1964053 (-)	201	WP_000180460.1	DUF1128 family protein	-
PQQ26_RS09675 (PQQ26_09675)	-	1964200..1964664 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
PQQ26_RS09680 (PQQ26_09680)	-	1964671..1964946 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
PQQ26_RS09685 (PQQ26_09685)	-	1965224..1966441 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
PQQ26_RS09690 (PQQ26_09690)	vraR	1966554..1967183 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
PQQ26_RS09695 (PQQ26_09695)	vraS	1967173..1968216 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
PQQ26_RS09700 (PQQ26_09700)	liaF	1968213..1968914 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
PQQ26_RS09705 (PQQ26_09705)	-	1968929..1969315 (-)	387	WP_001110178.1	hypothetical protein	-
PQQ26_RS09710 (PQQ26_09710)	map	1969532..1970290 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
PQQ26_RS09715 (PQQ26_09715)	-	1971046..1972032 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
PQQ26_RS09720 (PQQ26_09720)	-	1972221..1972634 (-)	414	WP_001643743.1	hypothetical protein	-
PQQ26_RS09725 (PQQ26_09725)	-	1972663..1972773 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=782967 PQQ26_RS09695 WP_001017131.1 1967173..1968216(-) (vraS) [Staphylococcus aureus strain ATCC 25923]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=782967 PQQ26_RS09695 WP_001017131.1 1967173..1968216(-) (vraS) [Staphylococcus aureus strain ATCC 25923]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1