Detailed information    

insolico Bioinformatically predicted

Overview

Name   braS   Type   Regulator
Locus tag   PQQ74_RS13345 Genome accession   NZ_CP117203
Coordinates   2676061..2676948 (-) Length   295 a.a.
NCBI ID   WP_000143419.1    Uniprot ID   A0A266CLT2
Organism   Staphylococcus aureus strain 2022QW-00133     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2671061..2681948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQQ74_RS13315 (PQQ74_13320) - 2671080..2671172 (+) 93 WP_010956583.1 hypothetical protein -
  PQQ74_RS13320 (PQQ74_13325) - 2671280..2671777 (-) 498 WP_001065268.1 glutathione peroxidase -
  PQQ74_RS13325 (PQQ74_13330) - 2671787..2672047 (-) 261 WP_001789910.1 hypothetical protein -
  PQQ74_RS13330 (PQQ74_13335) - 2672429..2672542 (-) 114 WP_001791776.1 hypothetical protein -
  PQQ74_RS13335 (PQQ74_13340) - 2673201..2675201 (-) 2001 WP_000776751.1 ABC transporter permease -
  PQQ74_RS13340 (PQQ74_13345) - 2675198..2675953 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  PQQ74_RS13345 (PQQ74_13350) braS 2676061..2676948 (-) 888 WP_000143419.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  PQQ74_RS13350 (PQQ74_13355) braR 2676959..2677624 (-) 666 WP_000697886.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  PQQ74_RS13355 (PQQ74_13360) - 2677650..2677850 (-) 201 WP_000604728.1 hypothetical protein -
  PQQ74_RS13360 (PQQ74_13365) - 2678048..2679472 (+) 1425 WP_000953744.1 alkaline phosphatase -
  PQQ74_RS13365 (PQQ74_13370) - 2679542..2679652 (+) 111 WP_001791296.1 hypothetical protein -
  PQQ74_RS13370 (PQQ74_13375) - 2679755..2680210 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  PQQ74_RS13375 (PQQ74_13380) - 2680455..2681216 (-) 762 WP_000323455.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 295 a.a.        Molecular weight: 34019.28 Da        Isoelectric Point: 6.0874

>NTDB_id=782868 PQQ74_RS13345 WP_000143419.1 2676061..2676948(-) (braS) [Staphylococcus aureus strain 2022QW-00133]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide


Download         Length: 888 bp        

>NTDB_id=782868 PQQ74_RS13345 WP_000143419.1 2676061..2676948(-) (braS) [Staphylococcus aureus strain 2022QW-00133]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(191-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A266CLT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braS Staphylococcus aureus N315

99.661

100

0.997