Detailed information NTG0780365

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: PN942_RS09010
• Genome accession: NZ_CP116807
• Coordinates: 1789680..1791308 (+)
• Length: 542 a.a.
• NCBI ID: WP_001186596.1
• Uniprot ID: -
• Organism: Mammaliicoccus lentus strain PVZ.22
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	1789680..1809476	1789680..1791308	within	0

Gene organization within MGE regions

Location: 1789680..1809476

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PN942_RS09010 (PN942_09005)	ccrB	1789680..1791308 (+)	1629	WP_001186596.1	recombinase family protein	Machinery gene
PN942_RS09015 (PN942_09010)	-	1791779..1792129 (+)	351	WP_000171449.1	SAUGI family uracil-DNA glycosylase inhibitor	-
PN942_RS09020 (PN942_09015)	-	1792214..1792525 (+)	312	WP_000833212.1	DUF960 family protein	-
PN942_RS09025 (PN942_09020)	-	1792544..1793065 (+)	522	WP_000836008.1	DUF1643 domain-containing protein	-
PN942_RS09030 (PN942_09025)	-	1793067..1793273 (+)	207	WP_001077283.1	hypothetical protein	-
PN942_RS09035 (PN942_09030)	-	1793266..1793589 (+)	324	WP_000088091.1	JAB domain-containing protein	-
PN942_RS09040 (PN942_09035)	-	1793784..1795676 (+)	1893	WP_182093640.1	site-specific integrase	-
PN942_RS09045 (PN942_09040)	-	1795683..1796060 (+)	378	WP_001041908.1	DUF6262 family protein	-
PN942_RS09050 (PN942_09045)	-	1796298..1796663 (+)	366	WP_000159127.1	metalloregulator ArsR/SmtB family transcription factor	-
PN942_RS09055 (PN942_09050)	-	1796656..1799070 (+)	2415	WP_182093641.1	cadmium-translocating P-type ATPase CadA	-
PN942_RS09060 (PN942_09055)	-	1799150..1799766 (+)	617	Protein_1758	CadD family cadmium resistance transporter	-
PN942_RS09065 (PN942_09060)	-	1800040..1800678 (-)	639	Protein_1759	sulfite exporter TauE/SafE family protein	-
PN942_RS09070 (PN942_09065)	cstR	1800678..1800938 (-)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
PN942_RS09075 (PN942_09070)	-	1801074..1802138 (+)	1065	WP_182093642.1	DsrE/DsrF/DrsH-like family protein	-
PN942_RS09080 (PN942_09075)	cstB	1802173..1803507 (+)	1335	Protein_1762	persulfide dioxygenase-sulfurtransferase CstB	-
PN942_RS09085 (PN942_09080)	-	1803621..1804769 (-)	1149	WP_000427807.1	ROK family transcriptional regulator	-
PN942_RS09090 (PN942_09085)	psm-mec	1805089..1805157 (+)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
PN942_RS09095 (PN942_09090)	mecI	1805242..1805613 (-)	372	WP_000369214.1	mecA-type methicillin resistance repressor MecI	-
PN942_RS09100 (PN942_09095)	mecR1	1805613..1807370 (-)	1758	WP_000952923.1	beta-lactam sensor/signal transducer MecR1	-
PN942_RS09105 (PN942_09100)	mecA	1807467..1809476 (+)	2010	WP_063852655.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62274.15 Da
• Isoelectric Point: 9.7334

>NTDB_id=780365 PN942_RS09010 WP_001186596.1 1789680..1791308(+) (ccrB) [Mammaliicoccus lentus strain PVZ.22]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide

• Length: 1629 bp

>NTDB_id=780365 PN942_RS09010 WP_001186596.1 1789680..1791308(+) (ccrB) [Mammaliicoccus lentus strain PVZ.22]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	86.531	100	0.865