Detailed information NTG0779492

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: POF58_RS08950
• Genome accession: NZ_CP116711
• Coordinates: 1748925..1751372 (-)
• Length: 815 a.a.
• NCBI ID: WP_038406098.1
• Uniprot ID: A0AB38VLN8
• Organism: Streptococcus agalactiae strain CNCTC 10/84 Cas9 AEKOrevertant
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1743925..1756372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
POF58_RS08925 (POF58_08925)	-	1744206..1745462 (+)	1257	WP_001285395.1	toxic anion resistance protein	-
POF58_RS08930 (POF58_08930)	hslO	1745602..1746477 (+)	876	WP_000357828.1	Hsp33 family molecular chaperone HslO	-
POF58_RS08935 (POF58_08935)	dusB	1746461..1747438 (+)	978	WP_000192732.1	tRNA dihydrouridine synthase DusB	-
POF58_RS08940 (POF58_08940)	-	1747559..1748200 (+)	642	WP_000909522.1	deoxynucleoside kinase	-
POF58_RS08945 (POF58_08945)	-	1748214..1748705 (+)	492	WP_000586899.1	GNAT family N-acetyltransferase	-
POF58_RS08950 (POF58_08950)	clpC	1748925..1751372 (-)	2448	WP_038406098.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
POF58_RS08955 (POF58_08955)	-	1751369..1751833 (-)	465	WP_000985641.1	CtsR family transcriptional regulator	-
POF58_RS08960 (POF58_08960)	-	1752006..1752467 (+)	462	WP_001106578.1	small multi-drug export protein	-
POF58_RS08965 (POF58_08965)	tsf	1752627..1753667 (-)	1041	WP_000808055.1	translation elongation factor Ts	-
POF58_RS08970 (POF58_08970)	rpsB	1753761..1754531 (-)	771	WP_000268454.1	30S ribosomal protein S2	-
POF58_RS08975 (POF58_08975)	ahpC	1754808..1755368 (+)	561	WP_000060538.1	alkyl hydroperoxide reductase subunit C	-

Sequence

Protein

• Length: 815 a.a.
• Molecular weight: 90597.14 Da
• Isoelectric Point: 6.0379

>NTDB_id=779492 POF58_RS08950 WP_038406098.1 1748925..1751372(-) (clpC) [Streptococcus agalactiae strain CNCTC 10/84 Cas9 AEKOrevertant]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITNYQ
FLEQSPALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDKEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAFEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKDKKHKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide

• Length: 2448 bp

>NTDB_id=779492 POF58_RS08950 WP_038406098.1 1748925..1751372(-) (clpC) [Streptococcus agalactiae strain CNCTC 10/84 Cas9 AEKOrevertant]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCAATTATCAA
TTTTTAGAGCAATCACCAGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAATTAGTTGGCTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
GAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATAAAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAAAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGATGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCTCGAGGCACTTTACGCACTGTTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCTCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCATTTGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACTATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCATCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGTCATAAGGATAAAAAGCATAAGCCTATTGCCGTAACCGAA
GATCATATTATGGCAACTCTCAGCCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACTGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGCCCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGCTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGCTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGACTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCAGAGTTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• AAA lid domain (AAA_lid_9) (375-471)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-132)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.355	99.632	0.761
clpC	Streptococcus thermophilus LMG 18311	72.883	100	0.729
clpC	Streptococcus thermophilus LMD-9	72.761	100	0.728
clpC	Streptococcus pneumoniae Rx1	68.673	99.877	0.686
clpC	Streptococcus pneumoniae D39	68.673	99.877	0.686
clpC	Streptococcus pneumoniae TIGR4	68.673	99.877	0.686
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.554	100	0.494
clpC	Bacillus subtilis subsp. subtilis str. 168	45.564	100	0.466
clpE	Streptococcus mutans UA159	46.395	78.282	0.363