Detailed information    

insolico Bioinformatically predicted

Overview

Name   radA   Type   Machinery gene
Locus tag   PHA78_RS11545 Genome accession   NZ_CP116604
Coordinates   2352622..2353989 (-) Length   455 a.a.
NCBI ID   WP_024377772.1    Uniprot ID   -
Organism   Streptococcus sp. HN38     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2352004..2366811 2352622..2353989 within 0


Gene organization within MGE regions


Location: 2352004..2366811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS11540 - 2352004..2352498 (-) 495 WP_099780042.1 carbonic anhydrase -
  PHA78_RS11545 radA 2352622..2353989 (-) 1368 WP_024377772.1 DNA repair protein RadA Machinery gene
  PHA78_RS11550 - 2353996..2354529 (-) 534 WP_002939962.1 histidine phosphatase family protein -
  PHA78_RS11555 - 2354536..2354979 (-) 444 WP_002939955.1 dUTP diphosphatase -
  PHA78_RS11560 - 2355497..2356363 (-) 867 WP_029175490.1 helix-turn-helix transcriptional regulator -
  PHA78_RS11565 - 2356701..2357270 (+) 570 WP_029175489.1 hypothetical protein -
  PHA78_RS11570 - 2357301..2357444 (+) 144 WP_161947137.1 hypothetical protein -
  PHA78_RS11575 - 2357813..2357935 (+) 123 WP_002939945.1 hypothetical protein -
  PHA78_RS11580 - 2358025..2358174 (-) 150 WP_161498491.1 hypothetical protein -
  PHA78_RS11585 - 2358190..2358549 (-) 360 WP_272158212.1 YbaN family protein -
  PHA78_RS11590 - 2358677..2359279 (+) 603 WP_015647489.1 NADPH-dependent FMN reductase -
  PHA78_RS11595 - 2359294..2360529 (+) 1236 WP_024376122.1 NAD(P)H-dependent oxidoreductase -
  PHA78_RS11600 - 2360610..2361404 (+) 795 WP_222357527.1 formate/nitrite transporter family protein -
  PHA78_RS11605 - 2361493..2363277 (-) 1785 WP_222311198.1 ABC transporter ATP-binding protein -
  PHA78_RS11610 - 2363417..2365126 (-) 1710 WP_272158213.1 ABC transporter ATP-binding protein -
  PHA78_RS11615 - 2365119..2365568 (-) 450 WP_029179478.1 MarR family winged helix-turn-helix transcriptional regulator -
  PHA78_RS11620 - 2365795..2366811 (+) 1017 WP_272158215.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 49845.30 Da        Isoelectric Point: 6.1911

>NTDB_id=778790 PHA78_RS11545 WP_024377772.1 2352622..2353989(-) (radA) [Streptococcus sp. HN38]
MTIAKKKTTFVCQSCEYHSPKYLGRCPNCGSWSSFVEEVEVAEVKNERVSLTGEKTRPMKLNEVSSIQVARTKTNMEEFN
RVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSTIGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSIRTE
IEKIKPDFLIIDSIQTIMSPDISSVQGSVSQVREVTNELMQIAKTNNIATFIVGHMTKEGTLAGPRTLEHMVDTVLYFEG
ERQHTFRILRAVKNRFGSTNEIGIFEMQSQGLVEVLNPSEVFLEERLDGATGSAIVVTMEGTRPILAEVQALVTPTMFGN
AKRTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVALASSYKDKPTNPQECFIGEIGLTGE
IRRVNRIEQRINEAAKLGFTKVYAPKNSLTGIKVPKEITVVGVTTIGEVLQKVFN

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=778790 PHA78_RS11545 WP_024377772.1 2352622..2353989(-) (radA) [Streptococcus sp. HN38]
ATGACCATCGCTAAGAAAAAAACAACCTTTGTCTGTCAATCCTGCGAGTACCACTCGCCCAAGTATCTGGGCCGTTGCCC
CAACTGTGGCTCCTGGTCTTCCTTTGTCGAGGAAGTGGAAGTCGCTGAAGTTAAGAACGAGCGGGTCAGCCTGACAGGTG
AGAAGACCCGTCCGATGAAGCTCAATGAAGTTTCCTCCATTCAAGTGGCCCGCACCAAGACCAATATGGAGGAGTTTAAC
CGCGTCCTCGGTGGTGGAGTGGTGCCGGGCAGCCTAGTTCTCATTGGAGGCGATCCAGGGATTGGCAAGTCCACCTTGCT
CCTGCAAGTATCCACTCAGCTGTCTACCATTGGCACCGTCCTCTATGTGTCGGGGGAGGAATCTGCCCAGCAGATTAAGC
TCCGTGCCGAGCGTTTGGGCGACATTGACAGCGAATTCTATCTCTATGCGGAGACCAATATGCAGAGCATTCGGACCGAG
ATTGAGAAAATCAAGCCAGATTTCCTGATTATCGATTCTATCCAGACCATTATGAGCCCTGACATCTCCAGCGTGCAAGG
ATCTGTCAGTCAGGTCCGTGAAGTGACCAATGAACTCATGCAGATTGCCAAGACCAACAATATTGCAACCTTTATCGTCG
GCCACATGACCAAGGAAGGAACCCTGGCTGGACCGCGGACCTTGGAGCATATGGTGGACACCGTTCTTTATTTTGAGGGC
GAGCGGCAGCACACCTTCCGTATCTTGCGGGCGGTCAAAAACCGCTTTGGATCCACCAACGAAATCGGCATTTTTGAAAT
GCAGTCGCAGGGTTTGGTCGAAGTTCTCAATCCAAGTGAGGTCTTTCTGGAAGAGCGTCTGGACGGGGCGACTGGCTCTG
CGATTGTCGTGACCATGGAGGGCACCCGTCCAATCCTTGCGGAAGTGCAGGCTCTGGTGACGCCGACCATGTTTGGCAAT
GCCAAGCGGACCACGACAGGACTGGATTTCAACCGTGCCAGCTTGATTATGGCGGTTTTGGAAAAACGGGCAGGCCTGCT
CCTCCAAAACCAAGATGCCTACCTCAAGTCAGCAGGCGGTGTCAAACTAGATGAGCCAGCTATTGACCTGGCAGTCGCAG
TTGCCCTTGCCTCCAGTTACAAGGATAAGCCGACCAACCCACAAGAGTGCTTTATAGGCGAAATCGGTCTGACAGGGGAA
ATCCGCCGCGTCAATCGGATTGAACAACGGATTAACGAAGCCGCCAAATTGGGCTTTACTAAGGTCTATGCCCCTAAAAA
TTCCCTGACAGGAATCAAGGTACCCAAGGAAATCACTGTTGTCGGCGTGACCACCATTGGCGAAGTCTTACAGAAAGTAT
TCAACTGA

Domains

Predicted by InterproScan.

Rubredoxin metal binding domain (Zn_ribbon_LapB)

(10-37)

AAA domain (AAA_25)

(64-220)

Subunit ChlI of Mg-chelatase (ChlI)

(363-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  radA Streptococcus mitis NCTC 12261

91.15

99.341

0.905
  radA Streptococcus pneumoniae Rx1

90.929

99.341

0.903
  radA Streptococcus pneumoniae D39

90.929

99.341

0.903
  radA Streptococcus pneumoniae R6

90.929

99.341

0.903
  radA Streptococcus pneumoniae TIGR4

90.929

99.341

0.903
  radA Streptococcus mitis SK321

90.708

99.341

0.901
  radA Bacillus subtilis subsp. subtilis str. 168

62.472

99.56

0.622