Detailed information NTG0778759

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: PHA78_RS02655
• Genome accession: NZ_CP116604
• Coordinates: 531820..534048 (-)
• Length: 742 a.a.
• NCBI ID: WP_272158420.1
• Uniprot ID: -
• Organism: Streptococcus sp. HN38
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 526820..539048

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PHA78_RS02635	-	527386..527826 (+)	441	WP_099780176.1	GNAT family N-acetyltransferase	-
PHA78_RS02640	ileS	527837..530626 (+)	2790	WP_099780175.1	isoleucine--tRNA ligase	-
PHA78_RS02645	-	530810..531118 (-)	309	WP_002938710.1	DUF1827 family protein	-
PHA78_RS02650	-	531173..531634 (-)	462	WP_002938708.1	NUDIX hydrolase	-
PHA78_RS02655	clpE	531820..534048 (-)	2229	WP_272158420.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
PHA78_RS02660	-	534272..534502 (+)	231	WP_024399156.1	DUF1797 family protein	-
PHA78_RS02665	-	534628..535317 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
PHA78_RS02670	-	535310..536044 (+)	735	WP_002943067.1	amino acid ABC transporter ATP-binding protein	-
PHA78_RS02675	-	536174..537022 (+)	849	WP_024378968.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
PHA78_RS02680	-	537363..537929 (+)	567	WP_105100962.1	hypothetical protein	-
PHA78_RS02685	-	537983..538483 (+)	501	WP_272158421.1	hypothetical protein	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82566.93 Da
• Isoelectric Point: 5.2782

>NTDB_id=778759 PHA78_RS02655 WP_272158420.1 531820..534048(-) (clpE) [Streptococcus sp. HN38]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDLDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLGNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=778759 PHA78_RS02655 WP_272158420.1 531820..534048(-) (clpE) [Streptococcus sp. HN38]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATCTTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATTATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGTTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATCACTATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAGGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAAGAAATTGAAGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTAAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGATATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGTTATG
TAGGCTACGAGGAAGCCGGTCAGCTAACTGAAAAAGTCCGCCGCAATCCTTACTCTCTCATCCTCTTGGATGAGGTAGAA
AAAGCCCACCCTGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACTATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTGGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTGCGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

• AAA lid domain (AAA_lid_9) (291-389)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-272)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.361	100	0.837
clpE	Streptococcus pneumoniae D39	82.361	100	0.837
clpE	Streptococcus pneumoniae R6	82.361	100	0.837
clpE	Streptococcus pneumoniae TIGR4	82.361	100	0.837
clpE	Streptococcus mutans UA159	82.377	100	0.832
clpC	Lactococcus lactis subsp. cremoris KW2	77.655	97.709	0.759
clpC	Bacillus subtilis subsp. subtilis str. 168	52.615	87.601	0.461
clpC	Streptococcus thermophilus LMD-9	48.408	84.636	0.41
clpC	Streptococcus mutans UA159	48.718	84.097	0.41
clpC	Streptococcus thermophilus LMG 18311	48.089	84.636	0.407
clpC	Streptococcus pneumoniae TIGR4	48	84.232	0.404
clpC	Streptococcus pneumoniae Rx1	48	84.232	0.404
clpC	Streptococcus pneumoniae D39	48	84.232	0.404
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.975	84.636	0.398