Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   PFZ59_RS12340 Genome accession   NZ_CP116393
Coordinates   2421043..2423271 (+) Length   742 a.a.
NCBI ID   WP_208582599.1    Uniprot ID   -
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2416043..2428271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS12310 (PFZ59_12310) - 2416809..2417138 (+) 330 WP_277697187.1 IS630 transposase-related protein -
  PFZ59_RS12315 (PFZ59_12315) - 2417212..2417658 (+) 447 WP_277697757.1 transposase -
  PFZ59_RS12320 (PFZ59_12320) - 2417965..2418813 (-) 849 WP_208582595.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  PFZ59_RS12325 (PFZ59_12325) - 2419047..2419781 (-) 735 WP_002943067.1 amino acid ABC transporter ATP-binding protein -
  PFZ59_RS12330 (PFZ59_12330) - 2419774..2420463 (-) 690 WP_208582597.1 amino acid ABC transporter permease -
  PFZ59_RS12335 (PFZ59_12335) - 2420589..2420819 (-) 231 WP_002938704.1 DUF1797 family protein -
  PFZ59_RS12340 (PFZ59_12340) clpE 2421043..2423271 (+) 2229 WP_208582599.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  PFZ59_RS12345 (PFZ59_12345) - 2423457..2423918 (+) 462 WP_002938708.1 NUDIX hydrolase -
  PFZ59_RS12350 (PFZ59_12350) - 2423973..2424281 (+) 309 WP_002938710.1 DUF1827 family protein -
  PFZ59_RS12355 (PFZ59_12355) - 2424586..2425432 (+) 847 WP_277697006.1 IS630 family transposase -
  PFZ59_RS12360 (PFZ59_12360) - 2425602..2426858 (+) 1257 WP_277697823.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 82581.00 Da        Isoelectric Point: 5.3491

>NTDB_id=777116 PFZ59_RS12340 WP_208582599.1 2421043..2423271(+) (clpE) [Streptococcus suis strain SS/UPM/MY/F001]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQVEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=777116 PFZ59_RS12340 WP_208582599.1 2421043..2423271(+) (clpE) [Streptococcus suis strain SS/UPM/MY/F001]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAACATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCTACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAGCCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCGGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTAGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAAGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGATTTAAAAGCCCATGTTATCGGACAAG
TTGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGATATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTGGTCGGTGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGTCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACCATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCGAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(153-272)

AAA lid domain (AAA_lid_9)

(291-389)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(647-721)

AAA domain (Cdc48 subfamily) (AAA_2)

(476-639)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.228

100

0.836
  clpE Streptococcus pneumoniae D39

82.228

100

0.836
  clpE Streptococcus pneumoniae R6

82.228

100

0.836
  clpE Streptococcus pneumoniae TIGR4

82.228

100

0.836
  clpE Streptococcus mutans UA159

82.243

100

0.83
  clpC Lactococcus lactis subsp. cremoris KW2

77.517

97.709

0.757
  clpC Bacillus subtilis subsp. subtilis str. 168

52.308

87.601

0.458
  clpC Streptococcus thermophilus LMD-9

48.089

84.636

0.407
  clpC Streptococcus mutans UA159

48.397

84.097

0.407
  clpC Streptococcus thermophilus LMG 18311

47.771

84.636

0.404
  clpC Streptococcus pneumoniae Rx1

47.68

84.232

0.402
  clpC Streptococcus pneumoniae D39

47.68

84.232

0.402
  clpC Streptococcus pneumoniae TIGR4

47.68

84.232

0.402
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.815

84.636

0.396