Detailed information NTG0777098

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: PFZ59_RS06325
• Genome accession: NZ_CP116393
• Coordinates: 1229449..1230498 (+)
• Length: 349 a.a.
• NCBI ID: WP_014638484.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SS/UPM/MY/F001
• Function: processing of CSP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1226907..1235355	1229449..1230498	within	0

Gene organization within MGE regions

Location: 1226907..1235355

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PFZ59_RS06315 (PFZ59_06315)	rsmD	1228445..1228984 (+)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
PFZ59_RS06320 (PFZ59_06320)	coaD	1228974..1229462 (+)	489	WP_277697752.1	pantetheine-phosphate adenylyltransferase	-
PFZ59_RS06325 (PFZ59_06325)	sepM	1229449..1230498 (+)	1050	WP_014638484.1	SepM family pheromone-processing serine protease	Regulator
PFZ59_RS06330 (PFZ59_06330)	-	1230576..1231423 (+)	848	WP_208580884.1	IS630 family transposase	-
PFZ59_RS06335 (PFZ59_06335)	-	1231584..1232225 (+)	642	WP_024399656.1	YutD-like domain-containing protein	-
PFZ59_RS06340 (PFZ59_06340)	rlmN	1232234..1233346 (+)	1113	WP_024406668.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
PFZ59_RS06345 (PFZ59_06345)	-	1233343..1233870 (+)	528	WP_029171487.1	VanZ family protein	-
PFZ59_RS06350 (PFZ59_06350)	-	1234063..1235319 (-)	1257	WP_277697763.1	ISL3 family transposase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37719.70 Da
• Isoelectric Point: 4.4261

>NTDB_id=777098 PFZ59_RS06325 WP_014638484.1 1229449..1230498(+) (sepM) [Streptococcus suis strain SS/UPM/MY/F001]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIAQFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALADDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLELGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKEDPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=777098 PFZ59_RS06325 WP_014638484.1 1229449..1230498(+) (sepM) [Streptococcus suis strain SS/UPM/MY/F001]
ATGAAGAAAAATAGGAAGTTAACCCTAATTGCGTCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACAACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAAGAATATTTCCGTATAGCACAGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTACTTGCCTTGGCGGATGATTCGACCTTTAAAAAAGTTCTTAATATTGCCGATACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAACTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAGAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATCGGCATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTTCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGTGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATCTTTTTCG
TACCAAACAATCCAGTTGATGTGGAAGTTTTGAAGGAAGATCCAAAGGCTAAAACCAACTATGAAGAAGCTAAGGAAGCT
GCGGAGAAAGCAGGATTGGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-311)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605